VetriScience Vetri-SAMe 90 mg Dog & Cat Tablets, 30 count

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Vetri-SAMe 90 is a synergistic blend of SAMe with Glutathione to support liver function. Optimal absorption of SAMe occurs in the small intestine. For this reason, tablets are enteric coated to protect the ingredients from stomach acid. A liver support formula with SAMe and Glutathione for dogs and cats.

Key Benefits
  • A veterinarian approved liver support formula with SAMe and glutathione for dogs and cats
  • Optimal absorption of SAMe occurs in the small intestine. For this reason, tablets are enteric coated to protect the ingredients from stomach acid and ensure they are delivered in tact to the small intestine where they can be effectively absorbed and utilized
  • Formulated to help maintain optimal health and function of your pet’s liver with the powerful antioxidant glutathione and S-adenosylmethionine
  • Since it’s great for dogs & cats, it’s an ideal supplement for multiple pet households with small canines and cats
  • National Animal Supplement Council (NASC) seal of approval so you know you’re buying a product developed to quality standards

HAZARDS TO ANIMALS: Safe use in pregnant animals or animals intended for breeding has not been proven. If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian. WARNING: For use in small dogs and cats only. For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a veterinarian immediately.

See all items by VetriScience

  • Item Number
  • Lifestage
    Adult, Senior, Puppy
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds, All Breeds
  • Food Form
  • Product Form
    Chewable Tablet
Nutritional Info

Active Ingredients: (Per Tablet) S-Adenosylmethionine (Same) 90 mg, L-Glutathione 10 mg.

Inactive Ingredients: Crospovidone, Magnesium Stearate, Microcrystalline Cellulose, Silicon Dioxide, Stearic Acid, Enteric Coating Ingredients Include: Glycerol Triacetate, Hydroxypropyl Methylcellulose Phthalate, Red #40, Titanium Dioxide, Yellow #10.

Feeding Instructions

Up to 12 lbs: Give 1 tablet daily. For best results, give on an empty stomach 1 hour prior to feeding.

Do not remove tablets from blister pack until used.

Store in a cool, dry place. Do not Refrigerate.


Where are your products made?

VetriScience' products are manufactured in the United States. However, we source the raw material for our products from both inside and outside the United States. Our raw material suppliers acquire high quality ingredients from all over the world. Depending on our needs and current market supplies, a particular raw material may be from 1 country in 1 batch, and from another country in another batch. For our raw materials, we require a Certificate of Analysis, which documents the quality, purity, and potency. This qualifies each raw material before accepting it for production.Our parent company - FoodScience' Corporation - is certified to operate under current Good Manufacturing Processes (cGMP) protocols. Under these protocols, we require that each ingredient in a formula be supplied with the respective Certificate of Analysis. This means that the supplier is required to test the ingredient for contaminants, such as heavy metals, microorganisms, and other physical or chemical parameters unique to the ingredient, before the ingredient is shipped. Any raw materials that do not meet our specifications are sent back to the supplier. Upon receipt of a raw material, it is tested for potency and other parameters outlined in the ingredient's specification sheet. Test results are compared against the established specifications.

Is it ok the double the recommended dose if I feel that my animal needs stronger/better support?

Please follow all dosing instructions stated on our packaging. VetriScience' calculates our dosing strength according to the animal's weight. Never increase dosing on a nutritional supplement without discussing it with your vet first.

Do VetriScience' products require refrigeration?

Refrigeration of our products is not recommended due to the fact that refrigeration produces moisture, which can degrade nutrients, change smell, and reduce the shelf life on nutritional supplements. Please follow the storage instructions on our labels.

Why should I include vitamins & supplements in my pet's diet?

Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet's exact health needs. Like in humans, vitamins and supplements can help support your pet's long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.

How often should I give this supplement to my pet?

It is recommended to give the suggested dosage based off your pet's weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.

Is this supplement safe to use with the medication my pet is currently taking?

If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.

My pet is allergic to certain ingredients, will this product be safe to use?

For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.

Does this product come in other product forms?

For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

Rating: 3.8 of 5 stars 8 Reviews 8 Reviews 3.9 out of 5 Stars

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75% of reviewersrecommend this product

Rating: 3.8 of 5 stars 3.9 / 5

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8 Reviews

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  • 2 out of 5 stars

    Really Disappointed

    By ThreeFurryTails on Mar 26, 2021

    I agree with a few other reviews, these are way too big for an average cat and I believe they are enteric coated for a reason. So cutting them really isn't an option. I'm already pilling my unwell cat multiple times a day and don't even want to bother trying these with their size. Disappointed as I really wanted her to be taking SAMe.

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  • 5 out of 5 stars

    works for her doggy dementia

    By Goeybear on Jun 12, 2020

    Needed this because she was having problems associated with age.

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  • 4 out of 5 stars


    By Fire911mom on Feb 9, 2020

    We purchased this for our ten year old Border Collie mix Sophie Grace. She is in great shape but her liver numbers are not looking great due to her age. Our vet recommended that we start her on this.

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  • 3 out of 5 stars

    Tablets are huge

    By Cathy on Oct 29, 2019

    For a cat these tablets are HUGE. Unless you are looking to dose a Maine Coon or a tiger...these are very difficult to get into an average cat. Very disappointed.

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  • 5 out of 5 stars

    Vetr-SAMe 90 vs Denosyl

    By Couponqueen on Aug 22, 2019

    I believe the Vetri-SAMe 90 is the same or better than the more expensive brand Denosyl. It has the same ingredients and same purpose yet saves you money! I will continue to buy this from now on.

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  • 5 out of 5 stars

    Just what I was looking for!

    By kathyt on Oct 25, 2018

    I had been looking for a low-dosage (as you are not supposed to cut the tablets) SAMe product for my elderly feline and this is perfect! I had read that the tablets were a bit large but I have found that sometimes it is easier to poke a larger pill down the throat than a small one. I also have to give this cat 1/2 thyroid pill twice a day (they are very small) and I have to use a piece of 'pill-pocket' to make it larger. So the VetriScience Vetri-SAMe 90mg works great for me!!!

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  • 3 out of 5 stars

    Pills are too big for a cat

    By Annabelle on Mar 9, 2017

    Although this supplement says it is for cats, I feel the pills were too big to safely give even my large cat. I can't speak to the effectiveness since I didn't end up using them.

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  • 4 out of 5 stars

    Works if you can get it in!

    By HeidiPipersmom on Jun 24, 2016

    Hi, I've used SAMe for a sick cat and it seemed to work very well. Now I have another cat with liver issues and he needs it but he is very pill averse. I cannot get it in him without seriously compromising his quality of life and our relationship. I REALLY wish this could be in a good -tasting chewable form. My cats love the lysine chew. I'd be willing to have it less absorbable (I know it's in a form to make it to the small intestine intact) and feed more and pay more.

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