Vet's Best Comfort Calm Dog Supplement, 30 count

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Vet's Best Comfort Calm supplement for dogs helps ease and reduce anxiety and tension from everyday stresses. Vet's Best calming aid for dogs use key natural ingredients (tryptophan and valerian root) helps your pet calm and relaxed. Perfect large breed dogs and small breed dogs 10 months and older. Can be given every 6 to 8 hours (use as directed).

Key Benefits
  • Veterinarian recommended natural comfort calm supplement for all sizes of dogs 10 months or older
  • Soothing mix of tryptophan and valerian root promotes a sense of relaxation and mental alertness without drowsiness
  • Give one hour before any stressful event such as traveling, big events, or even vet visits
  • Helps ease and reduce anxiety and tension from everyday stresses
  • National Animal Supplement Council (NASC) seal of approval so you know you’re buying a product developed to quality standards

Safe use in pregnant animals or animal intended for breeding has not been proven. If the animal's condition does not improve, stop product administration and consult your veterinarian. For animal use only. Keep out of the reach of children and other animals. In case of accidental overdose, contact a veterinarian immediately.

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  • Item Number
  • Breed Size

    Small Breeds, Medium Breeds, Large Breeds

  • Food Form


  • Lifestage

    Adult, Senior, Puppy

  • Product Form

    Chewable Tablet

Nutritional Info

Active Ingredients: (Per Chewable Tablet) 5-Hydroxytryptophan (25 mg), Valerian Root (25 mg ).

Inactive Ingredients: Apple Powder, Apple Pectin, Brewers Yeast, Calcium Carbonate, Liver (Defatted Pork), Magnesium Stearate, and Natural Flavorings.

Guaranteed Analysis
5-Hydroxytryptophan 25 mg
Valerian Root 25 mg
Feeding Instructions

Give 1 hour before any stressful event. Number of tablets can be repeated if needed just prior to event, and again every 6 - 8 hours as needed.


Holistic Care and Well-Being

Vet's Best holistic remedies for cats and dogs are veterinarian-recommended supplements that are safe and gentle enough to use on a regular basis. Each formula contains herbal extracts and natural ingredients for a healthy, happy pet.

Holistic Care and Well-Being
Hairball Relief Digestive Aids

Supplements for Cats

Vet's Best supplements for cats are perfectly formulated using wholesome ingredients for the daily maintenance and concerns of your favorite kitty.

Hairball Relief Digestive Aids: These tasty, chicken-flavored chewable digestive aids also contain an abundance of natural ingredients like slippery elm bark, marshmallow and papaya extract, an excellent source of vitamin A and E to effectively remedy hairballs. They're also easy to break up into smaller pieces for even easier digestion.

Urinary Tract Support: These all-natural chewable tablets are made with cranberry, parsley and horsetail to help maintain healthy acidic and free-flowing urinary tracts.

Supplements for Dogs

Vet's Best supplements for dogs are made with potent herbs and extracts to support your best buddy's day-to-day needs.


Joints: Hip + Joint Natural Formula and Advanced Hip + Joint are made with glucosamine and chondroitin for better joint mobility. Help address aching joints with Vet's Best Aches + Pains, the potent aspirin-free formula that contains active ingredients like glucosamine HCL, MSM, bromelain, yucca and white willow bark to support very active or senior dogs.


Calming: Vet's Best Travel Calm and Comfort Calm supplements are both made with special key ingredients including valerian root, tryptophan and ginger to help keep your pup calm during stressful situations like travel, storms or loud noises.

Seasonal Allergy

Seasonal Allergy: This seasonal allergy support supplement helps your pup maintain histamine levels and skin health with its key natural ingredients that include nettle, perilla leaf and citrus.

Gas Busters

Gas Busters: Vet's Best Gas Busters are chewable supplements made with ginger root, slippery elm and parsley to offer your dog relief from occasional gas, bloating and mild stomach upset.

Healthy Coat Shed + Itch

Healthy Coat Shed + Itch: Daily use of these vitamins will help your special pup maintain normal and healthy levels of shedding. It's packed with omega-6 and 3 fatty acids to support a shiny coat and alleviate itchy, dry skin.

About Vet's Best

Vet's Best is a part of The Bramton Company, LLC pet care products and solutions. These holistic products were developed by veterinarian Dr. Dawn Curie Thomas in the 1980s to help fill the market needs for more natural pet care solutions. Through dedicated research, Dr. Thomas created formulas that promote wellness without the use of harsh chemicals.

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About Vet's Best
Customer Reviews
72 Reviews 72 Reviews 3.8 out of 5 Stars

77% Recommend

77% of reviewersrecommend this product

3.8 / 5

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Showing 1-10 of 72 Reviews

  • Amazing works great!!!!!

    By on

    Works amazing makes my dog sleepy so I only give it to him when his anxiety is out of control!!! But love the product and the price :)

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  • They Do Work

    By on

    I have used these in the past and they work. Had to stop using as I could no longer buy them locally.

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  • Great for stressful situations!

    By on

    We give these to our pup when we get into a stressful situation: lots of people in the house, traveling long distances, etc. This keeps him calmer and less stressed than anything else we've tried.

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  • Bark no more...

    By on

    These chewable tabs are great.. my dog loves them and they work!! They are a lot cheaper than his script for anxiety.. thanks chewy :)

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  • Didn’t make any difference

    By on

    Didn’t help at all. No difference I could see with calming my dog.

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  • comfort calm

    By on

    I have only tried this once so far and it worked to calm her for guests coming to the house just fine. The dose for large dogs was fine. Will try next for a trip to the vets.

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  • Vets best anxiety

    By on

    Works great. Gave it to her for storms and 4th of July and she handled it a lot better.

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  • Dog needs prozac!!!

    By on Top 500 Contributor

    This doesn't seem to be working like I thought it would. Our dog cries when it sees a cat (we have 2) and cries when her daddy is on the computer upstairs. Lord, you should hear her when she goes to the vet!!! She is a deaf pitbull we rescued and we are paying for our good deed!

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  • Comfort Calm Works for my Rotty

    By on

    The rotty we got last has been a bit more high strung than our previous dogs. The wind rattles the doors or the blinds or the drapes and that upsets her. The fireworks are the worst however causing real trouble. Bella is 100 lbs and we followed the dosing. We have found that the gentling that happens is not sleep and not dropped like tranquilizing has been with her. We have had good luck with Comfort Calm.

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  • Doesn't work and dog hates them

    By on Top 1000 Contributor

    It's like pulling teeth trying to get my dog to eat these. Normally she'll eat just about anything but she hates these. When I finally get her to take these, I can't tell a diference. I'll stick with other brands

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