Vet's Best Comfort Calm Dog Supplement, slide 1 of 1

Vet's Best Comfort Calm Dog Supplement, 30 count

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Help keep your furry fella from freaking out with Vet's Best Comfort Calm Dog Supplement. This calming aid for dogs is veterinarian formulated with a premium blend of natural ingredients. It includes a soothing mix of tryptophan, valerian root and more that is optimized for absorption and digestion. This calming supplement is designed to help relieve anxiety and reduce stress due to fireworks, thunderstorms, hyperactivity, boarding, noise, separation anxiety, grooming and travel. It’s crafted into a convenient chewable tablet that’s paw-fect for puppers ten months or older.

Key Benefits
  • Calming supplements for your dog.
  • Paw-fect for dogs 10 months or older.
  • Veterinarian formulated with a premium blend of natural ingredients.
  • Features the National Animal Supplement Council (NASC) Seal of Approval.
  • Made in the USA.

Safe use in pregnant animals or animal intended for breeding has not been proven. If the animal's condition does not improve, stop product administration and consult your veterinarian. For animal use only. Keep out of the reach of children and other animals. In case of accidental overdose, contact a veterinarian immediately.

See all items by Vet's Best

  • Item Number
  • Lifestage
    Adult, Senior, Puppy
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds, All Breeds
  • Food Form
  • Product Form
    Chewable Tablet
Nutritional Info

Active Ingredients: (Per Chewable Tablet) 5-Hydroxytryptophan (25 mg), Valerian Root (25 mg ).

Inactive Ingredients: Apple Powder, Apple Pectin, Brewers Yeast, Calcium Carbonate, Liver (Defatted Pork), Magnesium Stearate, and Natural Flavorings.

Guaranteed Analysis
5-Hydroxytryptophan25 mg
Valerian Root25 mg
Feeding Instructions

Give 1 hour before any stressful event. Number of tablets can be repeated if needed just prior to event, and again every 6 - 8 hours as needed.


Why should I include vitamins & supplements in my pet’s diet?

Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet’s exact health needs. Like in humans, vitamins and supplements can help support your pet’s long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.

How often should I give this supplement to my pet?

It is recommended to give the suggested dosage based off your pet’s weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.

Is this supplement safe to use with the medication my pet is currently taking?

If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.

My pet is allergic to certain ingredients, will this product be safe to use?

For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.

Does this product come in other product forms?

For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

Holistic Care and Well-Being

Vet's Best holistic remedies for cats and dogs are veterinarian-recommended supplements that are safe and gentle enough to use on a regular basis. Each formula contains herbal extracts and natural ingredients for a healthy, happy pet.

Holistic Care and Well-Being
Hairball Relief Digestive Aids

Supplements for Cats

Vet's Best supplements for cats are perfectly formulated using wholesome ingredients for the daily maintenance and concerns of your favorite kitty.

Hairball Relief Digestive Aids: These tasty, chicken-flavored chewable digestive aids also contain an abundance of natural ingredients like slippery elm bark, marshmallow and papaya extract, an excellent source of vitamin A and E to effectively remedy hairballs. They're also easy to break up into smaller pieces for even easier digestion.

Urinary Tract Support: These all-natural chewable tablets are made with cranberry, parsley and horsetail to help maintain healthy acidic and free-flowing urinary tracts.

Supplements for Dogs

Vet's Best supplements for dogs are made with potent herbs and extracts to support your best buddy's day-to-day needs.


Joints: Hip + Joint Natural Formula and Advanced Hip + Joint are made with glucosamine and chondroitin for better joint mobility. Help address aching joints with Vet's Best Aches + Pains, the potent aspirin-free formula that contains active ingredients like glucosamine HCL, MSM, bromelain, yucca and white willow bark to support very active or senior dogs.


Calming: Vet's Best Travel Calm and Comfort Calm supplements are both made with special key ingredients including valerian root, tryptophan and ginger to help keep your pup calm during stressful situations like travel, storms or loud noises.

Seasonal Allergy

Seasonal Allergy: This seasonal allergy support supplement helps your pup maintain histamine levels and skin health with its key natural ingredients that include nettle, perilla leaf and citrus.

Gas Busters

Gas Busters: Vet's Best Gas Busters are chewable supplements made with ginger root, slippery elm and parsley to offer your dog relief from occasional gas, bloating and mild stomach upset.

Healthy Coat Shed + Itch

Healthy Coat Shed + Itch: Daily use of these vitamins will help your special pup maintain normal and healthy levels of shedding. It's packed with omega-6 and 3 fatty acids to support a shiny coat and alleviate itchy, dry skin.

About Vet's Best

Vet's Best is a part of The Bramton Company, LLC pet care products and solutions. These holistic products were developed by veterinarian Dr. Dawn Curie Thomas in the 1980s to help fill the market needs for more natural pet care solutions. Through dedicated research, Dr. Thomas created formulas that promote wellness without the use of harsh chemicals.

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About Vet's Best
Rating: 3.7 of 5 stars 88 Reviews 88 Reviews 3.8 out of 5 Stars

79% Recommend

79% of reviewersrecommend this product

Rating: 3.7 of 5 stars 3.8 / 5

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88 Reviews

Showing 1-10 of 88 Reviews

  • 5 out of 5 stars

    Comfort calm chews, vets best

    By KIMMIE on Feb 12, 2021

    These work great 2 of our dogs were really excited . n in within 20 min she was under the blankets snoring away n the other one asleep as well

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  • 3 out of 5 stars

    depends on the animal

    By lanne on Mar 24, 2021

    it did not help our dog. :( she did not stay calm, she had issues in ever way etc.

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  • 4 out of 5 stars

    Best Choice Vets Best

    By veggiegirl on Dec 11, 2020

    Trying most calming chews on the market, this tablet seems to work the best for a Wheaton Terrier mix who has severe separation anxieties. She gets a chew daily to help keep her calm throughout the day.

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  • 5 out of 5 stars

    So Surprised

    By Donna on Oct 13, 2020

    I really did not expect too much when I purchased these but i was wrong. They really do calm down the dog. Family came to visit with their dog. The two dogs together were like excited two year olds, running, jumping, not paying any attention to commands. My dog is a 7 month old Border collie x queensland Healer and theirs is a 3 year old Lab. Within a half an hour of giving the dogs their pills, which they wolfed down. They became mellow. I highly recommend this product.

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  • 4 out of 5 stars

    Calms my rambunctious puppy!

    By Rhsgirl on Aug 8, 2020

    When we leave her in the crate to run errands I give her one tablet an hour prior to departing. Seems to calm her for a reasonable time and she doesn’t tear her bedding up in the crate as she used to.

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  • 1 out of 5 stars

    Sorry didn't work

    By Lana on Aug 27, 2020

    I'm so sorry for giving a bad review but it just didn't work at all for my dog.

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  • 5 out of 5 stars

    These really do help my Girls.

    By ServiceReviewer on Apr 1, 2020

    When a visitor comes over or another dog my girls go super hyper. So I use these to calm them ahead of time and they are very chill. It doesnt make them lazy but it helps keep them from jumping all over the visitor. We are working on behavior correction but this is great for the mean time.

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  • 4 out of 5 stars

    You guys are great

    By Lynette on Jul 5, 2020

    My dog did calm down with this product she was definitely afraid of the fire works

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  • 4 out of 5 stars

    These work pretty good

    By Krista on Jan 22, 2020

    I have a two year old Great Pyrenees who gets hyper and stressed out when changes occur. Recently my family and I had to temporarily move in with my uncle and his fiancé, talk about change and stress. When we got these he calmed down with only one. Instead of the four which is the recommended dosage for a 100+ lb dog.

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  • 5 out of 5 stars

    Comfort Calm

    By Elvismills on Aug 6, 2019

    This is a wonderful product for my dog. He is a rescue dog and has a tendency to get distressed when left alone. This helps immensely. Txs Chewy

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