Vet's Best Comfort Calm Dog Supplement, slide 1 of 1

Vet's Best Comfort Calm Dog Supplement, 30 count

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Help keep your furry fella from freaking out with Vet's Best Comfort Calm Dog Supplement. This calming aid for dogs is veterinarian formulated with a premium blend of natural ingredients. It includes a soothing mix of tryptophan, valerian root and more that is optimized for absorption and digestion. This calming supplement is designed to help relieve anxiety and reduce stress due to fireworks, thunderstorms, hyperactivity, boarding, noise, separation anxiety, grooming and travel. It’s crafted into a convenient chewable tablet that’s paw-fect for puppers ten months or older.

Key Benefits
  • Calming supplements for your dog.
  • Paw-fect for dogs 10 months or older.
  • Veterinarian formulated with a premium blend of natural ingredients.
  • Features the National Animal Supplement Council (NASC) Seal of Approval.
  • Made in the USA.

Safe use in pregnant animals or animal intended for breeding has not been proven. If the animal's condition does not improve, stop product administration and consult your veterinarian. For animal use only. Keep out of the reach of children and other animals. In case of accidental overdose, contact a veterinarian immediately.

See all items by Vet's Best

  • Item Number
  • Lifestage
    Adult, Senior, Puppy
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds, All Breeds
  • Food Form
  • Product Form
    Chewable Tablet
Nutritional Info

Active Ingredients: (Per Chewable Tablet) 5-Hydroxytryptophan (25 mg), Valerian Root (25 mg ).

Inactive Ingredients: Apple Powder, Apple Pectin, Brewers Yeast, Calcium Carbonate, Liver (Defatted Pork), Magnesium Stearate, and Natural Flavorings.

Guaranteed Analysis
5-Hydroxytryptophan25 mg
Valerian Root25 mg
Feeding Instructions

Give 1 hour before any stressful event. Number of tablets can be repeated if needed just prior to event, and again every 6 - 8 hours as needed.


Why should I include vitamins & supplements in my pet’s diet?

Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet’s exact health needs. Like in humans, vitamins and supplements can help support your pet’s long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.

How often should I give this supplement to my pet?

It is recommended to give the suggested dosage based off your pet’s weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.

Is this supplement safe to use with the medication my pet is currently taking?

If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.

My pet is allergic to certain ingredients, will this product be safe to use?

For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.

Does this product come in other product forms?

For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

Holistic Care and Well-Being

Vet's Best holistic remedies for cats and dogs are veterinarian-recommended supplements that are safe and gentle enough to use on a regular basis. Each formula contains herbal extracts and natural ingredients for a healthy, happy pet.

Holistic Care and Well-Being
Hairball Relief Digestive Aids

Supplements for Cats

Vet's Best supplements for cats are perfectly formulated using wholesome ingredients for the daily maintenance and concerns of your favorite kitty.

Hairball Relief Digestive Aids: These tasty, chicken-flavored chewable digestive aids also contain an abundance of natural ingredients like slippery elm bark, marshmallow and papaya extract, an excellent source of vitamin A and E to effectively remedy hairballs. They're also easy to break up into smaller pieces for even easier digestion.

Urinary Tract Support: These all-natural chewable tablets are made with cranberry, parsley and horsetail to help maintain healthy acidic and free-flowing urinary tracts.

Supplements for Dogs

Vet's Best supplements for dogs are made with potent herbs and extracts to support your best buddy's day-to-day needs.


Joints: Hip + Joint Natural Formula and Advanced Hip + Joint are made with glucosamine and chondroitin for better joint mobility. Help address aching joints with Vet's Best Aches + Pains, the potent aspirin-free formula that contains active ingredients like glucosamine HCL, MSM, bromelain, yucca and white willow bark to support very active or senior dogs.


Calming: Vet's Best Travel Calm and Comfort Calm supplements are both made with special key ingredients including valerian root, tryptophan and ginger to help keep your pup calm during stressful situations like travel, storms or loud noises.

Seasonal Allergy

Seasonal Allergy: This seasonal allergy support supplement helps your pup maintain histamine levels and skin health with its key natural ingredients that include nettle, perilla leaf and citrus.

Gas Busters

Gas Busters: Vet's Best Gas Busters are chewable supplements made with ginger root, slippery elm and parsley to offer your dog relief from occasional gas, bloating and mild stomach upset.

Healthy Coat Shed + Itch

Healthy Coat Shed + Itch: Daily use of these vitamins will help your special pup maintain normal and healthy levels of shedding. It's packed with omega-6 and 3 fatty acids to support a shiny coat and alleviate itchy, dry skin.

About Vet's Best

Vet's Best is a part of The Bramton Company, LLC pet care products and solutions. These holistic products were developed by veterinarian Dr. Dawn Curie Thomas in the 1980s to help fill the market needs for more natural pet care solutions. Through dedicated research, Dr. Thomas created formulas that promote wellness without the use of harsh chemicals.

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About Vet's Best
Rating: 3.7 of 5 stars 82 Reviews 82 Reviews 3.8 out of 5 Stars

78% Recommend

78% of reviewersrecommend this product

Rating: 3.7 of 5 stars 3.8 / 5

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82 Reviews

Showing 1-10 of 82 Reviews

  • 5 out of 5 stars

    These really do help my Girls.

    By on

    When a visitor comes over or another dog my girls go super hyper. So I use these to calm them ahead of time and they are very chill. It doesnt make them lazy but it helps keep them from jumping all over the visitor. We are working on behavior correction but this is great for the mean time.

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  • 4 out of 5 stars

    You guys are great

    By on

    My dog did calm down with this product she was definitely afraid of the fire works

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  • 4 out of 5 stars

    These work pretty good

    By on

    I have a two year old Great Pyrenees who gets hyper and stressed out when changes occur. Recently my family and I had to temporarily move in with my uncle and his fiancé, talk about change and stress. When we got these he calmed down with only one. Instead of the four which is the recommended dosage for a 100+ lb dog.

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  • 5 out of 5 stars

    Fabulous Product!

    By on

    This is really super, it works so well. My dog wasen't a huge fan of the taste, but when I told her it was good she gobbled it down, lol. We travel in our moterhome alot so when we were at a campground and I had some errands to run, my mom watched my dog. She gets seperation anxity and mom said she wouldn't stop whining and pacing. Before I left again the next day I gave her one of these...Voila! Mom says she was as chill and easygoing as shes ever seen her! Amazing product!

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  • 5 out of 5 stars

    Comfort Calm

    By on

    This is a wonderful product for my dog. He is a rescue dog and has a tendency to get distressed when left alone. This helps immensely. Txs Chewy

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  • 1 out of 5 stars

    Didn't help my dogs at all.

    By on

    My Bassett has anxiety issues. This did no good. I will keep her on what the vet prescribed. They have a great vet.

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  • 3 out of 5 stars

    Didn't see any benefit

    By on

    I bought these for my one German Shepherd. N I didn't see any difference in behavior. But I continued to give her the tablets til they were gone, n still didn't see a difference. But I think her problem was more severe than these tablets were meant to help with. I use another product of this company n have had excellent results with that one. I think this product is worth trying if ur dogs situation isn't as bad as mine.

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  • 5 out of 5 stars


    By on

    I love comfort calm, keeps my lab sleeping and comfortable for six hours.

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  • 3 out of 5 stars

    My dog will not eat

    By on

    Although Chocolate will not eat this I will try other ways because I believe it's a great item. Any suggestions please post.

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  • 5 out of 5 stars

    Amazing works great!!!!!

    By on

    Works amazing makes my dog sleepy so I only give it to him when his anxiety is out of control!!! But love the product and the price :)

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