Zobuxa (Enrofloxacin) Tablets for Dogs & Cats

Prescription Item

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In stock
Strength: 22.7-mg
  • 22.7-mg In stock
  • 68-mg In stock
  • 136-mg In stock
  • 272-mg In stock
Count: 1 tablet
  • 1 tablet In stock

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Zobuxa is a prescription, broad-spectrum antibiotic that treats infections caused by bacteria susceptible to enrofloxacin. Administered once a day, it comes in a convenient, chewable tablet.


Zobuxa is a once-a-day, broad-spectrum antibiotic. It is often prescribed by veterinarians to treat infections caused by susceptible bacteria in companion animals.

Possible Side Effects

In rare instances, use of this product in cats has been associated with Retinal Toxicity. Dosage should not exceed 5 mg/kg of body weight once daily in cats. Enrofloxacin is contraindicated in dogs and cats known to be hypersensitive to quinolones.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting Zobuxa.


Consult your veterinarian before using enrofloxacin with vitamins and supplements, probenecid, oral cyclosporine, since interactions may occur. Do not use within 2 hours of giving antacids, sucralfate, or iron, aluminum, calcium, or dairy products, as absorption will be decreased. May cause increased theophylline blood levels.

  1. Prescribing Information

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  • Item Number
  • Common Brand Name(s)
  • Generic Name
  • Dosage Measure
    Use according to your veterinarian's instructions.
  • For Use With
    Dogs & Cats
  • Brand
  • Product Form
    Chewable Tablet
  • Health Condition
    Skin Infections, Respiratory Infections, Urinary Tract Infections (UTI)
  • Drug Type


Recommended Dosage

Dogs: Administer orally, allowing for 5-20 mg/kg (2.27 to 9.07 mg/lb) of body weight. The dose may be given either as a single daily dose or divided into two equal daily doses, administered at 12-hour intervals. Follow instructions exactly as given, as dose selections will be based on clinical experience, severity, and the specific pathogen.

Cats: Administer orally, allowing for 5 mg/kg (2.27 mg/lb) of body weight. The dose may be given either as a single daily dose or divided into two equal daily doses, administered at 12-hour intervals. Continue dose for at least 2-3 days after symptoms stop, but for no more than 30 days.

Storage Instructions

Store at temperatures between 68° - 77°F.


What is Zobuxa?

Often prescribed to dogs and cats for the management of diseases associated with bacteria susceptible to enrofloxacin.

What are the benefits of Zobuxa?

  • Treats many types of infections caused by susceptible bacteria.
  • Easy once-a-day dose.

How is this medication given?

Use as directed by your veterinarian.

How does this medication work?

Enrofloxacin is a fluoroquinolone antibiotic. Fluoroquinolones interfere with bacterial DNA metabolism to kill the bacteria.

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