Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-oz bottle

By Zymox
Rated 4.5524 out of 5 stars
$14.99Chewy Price
$18.99Chewy Price
In Stock
FREE 1-3 day delivery on first-time orders over $35

About This Item


  • Gentle, enzymatic approach to provide natural and effective first aid care for wounds, cuts, hot spots and even mild skin infections.
  • LP3 Enzyme System reacts with the infectious pus and debris to form its antimicrobial properties. Even without antibiotics, this spray is effective against hot spots, wet eczema, pyoderma, Staphylococcus, MRSA, Epidermophyton (ringworm), and more.
  • The enzymes in Zymox install a natural protective topical barrier that creates an active residual effect that kills bacteria, fungus and viruses.
  • Hydrocortisone is included to reduce swelling and itch relief, resulting in a soothing treatment for your pet.
  • Made in the USA.

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Play Video: Learn More About Zymox From Our Team of Experts
Learn More About Zymox From Our Team of Experts

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Top IngredientsActive Ingredients: Hydrocortisone 1.0%., Inactive Ingredients: Aloe Vera, Benzoic Acid...Hydrocortisone 0.5%, Aloe Vera, Benzoic Acid...Glycerin, Purified Water, Propylene Glycol...Active: Hydrocortisone 1%, Pramoxine Hydrochloride 0.5%, Inactive: Propylene Glycol...N-Alkyl (50% C14, 40% C12, 10% C16)...
Health FeatureItch & Redness Remedy, Skin & Coat HealthItch & Redness Remedy, Skin & Coat HealthSkin & Coat HealthAllergy ReliefSkin & Coat Health
Breed SizeSmall Breeds, Medium Breeds, Large Breeds

Questions & Answers

20 Customer Questions

Will this treat a yeast infection in a dog?
Answer by ChewyJan 31, 2018
Yeast infections are caused by fungus. This item creates an active residual effect that kills bacteria, fungus and viruses.

Is it safe for a dog if they accidentally lick it?
Answer by ChewyJan 19, 2019
This spray is safe, gentle and non-toxic and worry-free if a pet licks application site.

Will this get rid of my dog's nail bed redness, swelling, and discoloration?
Answer by ChewyNov 14, 2017
This product kills bacteria, fungus, and viruses while providing relief and reducing inflammation on the affected area.

Is this safe to use on/in my dogs ears?
Answer by ChewyAug 28, 2017
This spray is for external use only.

ReviewsWrite a Review

Rated 4.5524 out of 5 stars
210 Ratings
Would recommend to a friend

206 Customer Reviews

Rated 5 out of 5 stars
By Circe on Aug 28, 2023

So far, so good

My cat developed small scabbed-over sores up the length of her spine. Vet was unable to determine etiology. I figured we should at least try to clear up the symptoms and found this on Chewy. We used Zymox once a day for approx a week on the affected area and the sores cleared up. Now, just waiting to see if the sores return.

Rated 5 out of 5 stars
By Karen on Oct 12, 2023

Zymox is great

I’ve used the Zymox for my dogs yeasty ears and it works wonders in cleaning them up. She has yeast dermatitis so I thought I’d try this. Works as good as the Zymox for ears.

Rated 4 out of 5 stars
By sandra on Oct 26, 2023

He is a very sensitive skin dog we tried a shot but he got use to it and nothing was working any more we tried this and he stopped being so itchy

Rated 5 out of 5 stars
By Vickio on Sep 24, 2023

topical spray

This stuff really works when the dog sits still long enough to get it on him.

Rated 5 out of 5 stars
By Pat on Jun 28, 2023

Zymox Topical Spray

This works very good. My pug has skin allergies and her paws are so chewed up. I like it helps her stop licking. Also I read that id she does like after it dries it wont hurt her. So far so goo.

Rated 4 out of 5 stars
By Queita on Aug 29, 2023

It helped my alley cats skin in less than four days. I wished they had a bigger bottle.

Rated 5 out of 5 stars
By Lillie on May 15, 2023

Great Stuff

Great wound treatment for our pets! Helps the healing process and soothes the scratchy areas.

Rated 5 out of 5 stars
By Peanut on Nov 3, 2022

Itchy cat

My cat has food allergies pretty bad. When he gets a sore this keeps him from itching/biting it more because it must taste gross & he foams when he licks it. It also heals the wound pretty quickly. Love it!

Rated 5 out of 5 stars
By Lwlprieb on Nov 11, 2022

Very effective

I bought this for my dog licking hot spot on front leg and it works very well. It stopped my dog from licking and healed the area.

Rated 3 out of 5 stars
By Jill on Aug 5, 2022

Very small so almost gone after a week

My dog had bad allergies and got a staph infection I have been giving this to help with the itching. However I haven't gave it to her 2 times a day as requested and it is almost gone so it goes very fast and haven't seen a noticeable difference in her skin.