Zymox Veterinary Strength Enzymatic Dog & Cat Leave-on Conditioner

By Zymox
Rated 4.4521 out of 5 stars


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$14.99Chewy Price
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This Item – Zymox Veterinary Strength Enzymatic Dog & Cat Leave-on Conditioner, 12-oz bottle
Rated 4.4521 out of 5 stars
$14.99Chewy Price

Spend $100, Get $30 eGift Card with code: FALL

Zymox Veterinary Strength Enzymatic Dog & Cat Shampoo, 12-oz bottle
Rated 4.4037 out of 5 stars
$14.99Chewy Price

Spend $100, Get $30 eGift Card with code: FALL

Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-oz bottle
Rated 4.5561 out of 5 stars
$14.99Chewy Price

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Total Price: $44.97

About This Item


  • Provides a powerful protective barrier against minor skin inflammation and irritation due to allergies, psoriasis and minor topical infections.
  • Proven antimicrobial LP3 Enzyme System inhibits, splits and destroys the offending organisms while leaving healthy cells alone.
  • The addition of vitamin D3 helps to relieve surface irritations and hydrate the skin.
  • Can be applied full strength to the problematic areas and left on to dry; lightly rinse or leave in for residual effectiveness. No greasy residue!
  • Made in the USA.

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Top IngredientsPurified Water,  Stearyl Alcohol, Cetyl Alcohol...*Ricinus Communis (Castor) Seed Oil, *Cocos Nucifera (Coconut) Oil, *Cera Alba (Beeswax)...Organic Cocoa Butter, Organic Sweet Almond Oil, Organic Coconut Oil...Organic Cocoa Butter, Organic Sweet Almond Oil, Organic Coconut Oil...Active Ingredients: Plantain, Calendula, Chickweed...
Health FeatureItch & Redness Remedy, Skin & Coat HealthItch & Redness Remedy, Paw Care, Sensitive SkinPaw CareSensitive SkinItch & Redness Remedy
LifestageAdult, SeniorPuppy, Adult, SeniorPuppy, Adult, SeniorAll LifestagesPuppy, Kitten, Adult, Senior, All Lifestages
Breed SizeSmall Breeds, Medium Breeds, Large BreedsSmall Breeds, Medium Breeds, Large BreedsAll BreedsSmall Breeds, Medium Breeds, Large Breeds

Questions & Answers

12 Customer Questions

what if my dog licks the rinse? Will it be harmful?
Answer by ChewyJan 26, 2019
The product is safe if licked by your pet.

Is it safe for cats?
Answer by ChewyNov 29, 2019
The Zymox Veterinary Strength Enzymatic Dog & Cat Leave-on Conditioner is safe for cats.

Can you periodically soak dogs paws in Zymox rinse?
Answer by ChewyAug 02, 2018
With no harsh ingredients, it’s gentle enough for routine use. You can use it as a leave-in conditioner for residual effectiveness, and apply it full strength to the most problematic areas.

How often can it be applied, can it be used daily?
Answer by ChewySep 27, 2019
This leave-on conditioner can be applied on daily.

ReviewsWrite a Review

Rated 4.4521 out of 5 stars
73 Ratings
Would recommend to a friend

73 Customer Reviews

Rated 5 out of 5 stars
By MillieTheBeagel on Aug 31, 2023

Relief in a Bottle

Vet recommended for dogs general itchiness. Followed vet's advice, mixing water and conditioner in a spray bottle to apply several times a week. Worked great. Continued to have problem areas, especially the undercarriage and paws. Applied it full strength as a lotion, what a relief! The dog settles right down and have applied on consecutive days with no issues on paws. Since starting lotion application on paws have cut way back on medicated mouse for paws as she has inter-digital cysts.

Rated 1 out of 5 stars
By JCB on Sep 1, 2023

Strong scent and very greasy as a leave-on

I purchased this to use for my cat and the pups I watch. It has a very powerful odor that smells like fragrance mixed with plastic. It is too greasy to use as a leave in conditioner on dry fur in my opinion but may be fine to rinse out or use a smaller amount on freshly shampooed fur.

Rated 5 out of 5 stars
By Pat on Jun 28, 2023

Zymox Shampoo and Cnditioner

I just bought these for my pug dog with skin allergies. I must say this works better than so many others I have used to treat her skin problems. I like the leave in conditioner such a great smell and no itching

Rated 5 out of 5 stars
By Greenboots on May 7, 2023

Smells Great!

My cat has very dry coat and allergies- I try everything to keep his hair from falling out. Only used this for a week. Put a dab in my palms and rub into coat once a day. It absorbs quickly and smells great! Makes the coat soft, shiny and moisturized. He doesn't mind or notice the treatment. Think it will help his coat

Rated 5 out of 5 stars
By Teddy on Apr 17, 2023

Really helps - sebaceous adenitis

My poodle has sebaceous adenitis, a disease that causes destruction of the sebaceous glands and thus incredibly dry damaged skin. I tried this on a whim and it really helps the extra dry spots! I apply it directly on the really bad spots while he’s dry and leave it on, and I mix it with water and another product in a spray bottle to treat his whole body. It smells great, doesn’t leave an icky residue, and seems to provide some good relief.

Rated 5 out of 5 stars
By Rose on Mar 11, 2023

Miracle for problem skin

We rescued a puppy who came to us in very poor health, among many other things she had bald patches all over and shed like you would not believe. The vet couldn't find anything obvious (like ringworm or mange), and she improved with months of proper nutrition and antiseptic treatments, but her shedding barely slowed down. She is short haired / smooth coated and threw hair off to such an extreme that vacuuming our bedroom weekly would fill up the canister TWICE. After months of bathing her with heavy moisturizing washes, Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Shampoo, giving her salmon oil and other supplements, and putting on prescription topicals every day, I was sort of at the end of my rope. Nothing slowed down the dander and hair flying off her at all times. Finally I tried this enzyme conditioner after reading the reviews for it and one million other possible products to try, and after only TWO BATHS with this she has a totally normal coat. I couldn't believe it. The first bath washed out the usual heaps of hair, second one was a lot but way less than before, and ever since then she's been totally normal. I rinsed it out like normal conditioner, too, though lightly to try to leave some behind. I still bathe her with it somewhat regularly but her shedding never increases between baths, so it's not entirely temporary like the normal moisturizing washes are. Cannot recommend this stuff enough. It is true that it is fragranced, but it's not that bad. I use fragrance-free everything (personal and household products) because strong fragrances give me migraines, but I'm not bowled over by the way this smells when I bathe my dog. I don't notice the smell lingering on her much, either, and it fades away quickly. For reference I'll often get a headache if I burn a single scented candle somewhere in the house. So I'm pretty sensitive, but your mileage may vary.

Rated 5 out of 5 stars
By Diego on Jul 10, 2023

Feeling good

If your pet has itchy skin than this is what you and your pet has been looking for

Rated 5 out of 5 stars
By Katherine on Jan 16, 2023

Soothes urine scalding in cats

My female cat has some incontinence and this awesome product has become part of our hygiene routine. Her bottom is shaved to try to keep the urine from soaking into her fur, yuck. Still, cat urine is super concentrated & very irritating to skin. I clean her off with unscented baby wipes, and once she dries, I apply this like a lotion to her genitals & on the underside of her tail. Some ointments and barrier creams we've tried in the past seemed to bother her, and she'd be scooting or biting at her back legs within a couple minutes of applying them. Not this product! She seems happy to have me put it on her. It's helped tremendously with her skin integrity--as much as our previous courses of topical steroids, but without the drawbacks. Use this product as liberally as you would use a lotion. The enzymes give the skin a chance to heal. This stuff is a soothing lotion and similar to a probiotic for the skin all in one.

Rated 5 out of 5 stars
By Greeney52 on Oct 19, 2022


For a year I have been treating him for skin allergy "Dermatitus" I was told. $60. a month for a shot first then that wore off in three weeks and turned to Apoquil. $60. a month for Apoquil as well. It worked for 9 months and wasn't effective anymore. Then took him to a new vet she and said try these products instead and gave me a couple sample packets which worked great so far at a month down the line. So I ordered the products together here at a $30. total a they should last three months or more at the level of use that Ska needs. Shampoo once a week and daily applications of the leave-on conditioner at full strength. These are concentrated so it doesn't take much for my Boston Terrier. SKA is doing pretty well with the shampoo and leave-on conditioner I'm using. Shampoo: https://www.chewy.com/zymox-veterinary-strength-enzymatic/dp/54796 Leave-on Conditioner: https://www.chewy.com/zymox-veterinary-strength-enzymatic/dp/54797 Pics: https://photos.app.goo.gl/dZikrkeKfajZbYNK7 Vet say's don't use oatmeal products!! Give these a try?

Rated 5 out of 5 stars
By SaraJ on Dec 7, 2022
Top 250 Contributor

works great!

Excellent cream rinse for our seasonal environmental allergy girl. We gentle rinse and leave most of it on. Smells great for days, makes her very soft, and seems to help with itching. Tip: In between washes, I rub some with water in my hands and massage it in. It refreshes and soothes and also works way better than a coat spray to make her smell great.