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Rated 4.7 out of 5 stars
4.7
$46.07 Chewy Price$46.07
($0.76/ea) Price per Unit($0.76/ea)
Autoship Price
- Prescription Item
Free delivery on first-time orders

PROIN® effectively treats urinary incontinence in dogs by strengthening the urethral sphincter muscle. Available in chewable tablets (25 mg, 50 mg, 75 mg), its liver-flavored formula makes administration easy and appealing to dogs and typically shows results within a few weeks, helping prevent accidents and restoring quality of life for both pets and owners.
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PROIN® has been trusted by veterinarians for nearly 15 years to safely and effectively treat urinary incontinence (UI) due to urethral sphincter hypotonus in dogs. Now, there's PROIN ER - a canine UI medication that's just as effective as PROIN with only one pill a day.
Ask your veterinarian about switching to PROIN ER today.
PROIN® IMPORTANT SAFETY INFORMATION:
The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases, death, including euthanasia, has been reported. Sudden death was sometimes preceded by vocalization or collapse.
Instances of dogs chewing through closed vials of PROIN® and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secured storage area out of the reach of pets in order to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN® Chewable tablets. Contact your veterinarian immediately if the dog ingests more tablets than prescribed or if other pets ingest PROIN® Chewable tablets.
PROIN® may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure.
The safe use of PROIN® in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. Contact your veterinarian if you notice restlessness or irritability, loss of appetite, the incontinence persists or worsens or any other unusual signs. See prescribing information for complete details regarding adverse events, warning and precautions.