Adams Flea & Tick Spot Treatment for Dogs, 61-150 lbs, 3 Doses (3-mos. supply)

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Help protect your pup with Adams Plus Flea & Tick Spot On! This topical spot treatment is made in the USA for extra-large dogs weighing between 61-150 pounds. Simply apply the quick-drying solution to your pet’s skin between the shoulder blades to help kill adult fleas, ticks (including those carrying Lyme disease), chewing lice and mosquitoes. This treatment, effective for 30 days, can also help break the life cycle of fleas and ticks by killing flea eggs, tick nymphs, and flea and tick larvae before they even hatch. Soon you’ll be able to enjoy all the snuggles from your sidekick without fear of pesky pests!

Key Benefits
  • Formulated to kill adult fleas, flea eggs, flea larvae, ticks, tick nymphs and tick larvae.
  • Helps kill and repel mosquitoes.
  • Each tube helps protect your pet from infestation for up to 30 days.
  • Dries quickly so your furry friend can get back to all the playing and petting.
  • Made in the USA.

Your pet may experience some temporary irritation at the site of application. If signs persist or become severe within a few days of application, consult your veterinarian immediately. Observe your pet following treatment. Sensitivities may occur after using ANY pesticide product on pets. Please read entire manufacturer’s insert prior to using product. Approved for use in breeding, pregnant, or nursing animals. Consult with veterinarian before using on sick, medicated or aged animals.

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

See all items by Adams

  • Item Number
  • Usage
  • Lifestage
    Adult, Puppy, Senior
  • Breed Size
    Giant Breeds
  • Product Form
    Liquid, Solution
  • Health Condition
    Fleas, Ticks

Active Ingredients: Etofenprox: 55.0%, Piperonyl Butoxide*: 10.0%, N-octyl Bicycloheptene Dicarboximide (MGK 264): 1.0%, Pyriproxyfen: 0.5%

Other Ingredients: 33.5%


Adams Plus Flea & Tick Spot On for Dogs works by application directly to the dog’s/puppy’s skin, not to the hair. When applying, manually push aside dog’s/puppy’s hair to allow direct application to the skin.

Note: Each package contains tubes for 3 applications.

To apply the Adams Plus Flea & Tick Spot On for Dogs treatment, use one disposable liquid tube for each application.

  • Bend at perforation and tear off first tube.
  • Hold tube upright and snap tip back, away from face and body.
  • The dog/puppy should be standing for easy application. Apply Adams Plus Flea & Tick Spot On for Dogs evenly to four or five spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of the solution at any one spot that could cause some of the solution to run off the side of the dog/puppy.
  • Do not spread Adams Plus Flea & Tick Spot On for Dogs by hand over the dog/puppy. Although the dog’s/puppy’s skin and hair oils will distribute the application over the entire dog/puppy, brushing the dog/puppy 12-24 hours after application will help to distribute the material over the skin.
  • Discard empty tube as described in Storage and Disposal.

Where is this product sourced from?

We source all our products from manufacturer approved distributors or directly from the manufacturers. Chewy takes pride in ensuring that our furry friends’ wellbeing is always our top priority. We have worked hard to partner with all of the manufactures to deliver 100% authentic products

About Adams

Total Flea Control

Total Flea Control

Stopping fleas and ticks takes a multi-pronged approach, so Adams has a whole line of products to help prevent, treat and eliminate biting pests for good. From shampoos to spot treatments to yard sprays and more, they help you make and keep your pets and home bite-free.

Healthy and Happy Pets, the Adams Way


Adams helps keep your best friends healthy by providing lasting protection from harmful pests and breaking the cycle of reinfestation.


Treating the areas of your home where fleas, ticks and larvae like to hide will make life more pleasant for everyone in your household.


Sold by veterinarians since 1975, Adams products are a tried and trusted name in flea and tick control that you can rely on.

About Adams

Adams has been making flea and tick control solutions trusted and sold by vets for over 40 years. They offer a complete line of topicals, collars, sprays, shampoos and indoor and outdoor household treatments to handle all your pest prevention, treatment and eradication needs. For a healthy pet and a happy home, trust Adams for long-lasting protection!

Shop Adams


Rating: 3.7 of 5 stars 11 Reviews 11 Reviews 3.7 out of 5 Stars

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82% Recommend

82% of reviewersrecommend this product

Rating: 3.7 of 5 stars 3.7 / 5

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11 Reviews

Showing 1-10 of 11 Reviews

  • 5 out of 5 stars

    Flea medicine

    By Nance on May 17, 2020

    It is so nice to be able to get flea medicine at a good price if you have a 12 pack I would like to know and I will order that next time

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  • 5 out of 5 stars

    Effective at a good price

    By Sandy319 on Mar 25, 2020

    Tried many spot on treatments that did not work. All the Adams products work well. They are very effective. The price is good compared to other brands that do not work as well. Would definitely recommend all the Adams products.

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  • 4 out of 5 stars

    Adam's flea control

    By Linda on May 17, 2020

    I like the Adams flea control where it's not Advantage it still works for me well my pups an it is affordable

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  • 5 out of 5 stars

    love chewy

    By Terri on Feb 18, 2020

    Great price for this product. I have 2 spoiled lg. dogs, which can be expensive. I always look for savings. Chewy is the best site. They have fast shipping, the best customer service, and good prices. Would recommend to everyone!

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  • 4 out of 5 stars

    Got it for my big dogs

    By Jaci on Jun 24, 2019

    I got this mainly to keep mosquitoes away from the dogs. We haven't had problems with fleas or ticks, but the mosquitoes are terrible this year. I loved that this actually goes up to 150lbs since both of my Great Danes are about that weight. The downside is that the treatment smells really bad and is super oily.

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  • 1 out of 5 stars

    Did not work

    By Irish893 on Jul 10, 2019

    I love Chewy but this product did not work on my Great Pyrenees. I am still bathing him in dawn and lavendar oil and picking fleas off of his coat. Looking for something more effective. Don't know why this was rated with five stars.

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  • 5 out of 5 stars

    New product same active ingredients as Bio Spot

    By Jack on May 30, 2019

    Used Bio Spot for more years than I can count on many dogs so I will try this product and see how it preforms. Just had one application so far and seems to work fine as he is in and out of the woods all the time.

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  • 5 out of 5 stars

    Is good as spray

    By Rocko on May 15, 2019

    Got all the ingredients but there is a little more this and little less I know Adam's has there stuff together just hope drops repel the little vampires as well as they spray cause high powered OFF ain't got nothin on it.

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  • 1 out of 5 stars

    honestly didn’t work at all...

    By JessStolensoul on Jul 6, 2019

    Had to switch back to the super smelly Adams flea spray because this left my pup riddled with fleas. Madness.

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  • 1 out of 5 stars

    Not working

    By Dane on Jun 16, 2019

    Doesn't seem to be working on my dog it's been a week already

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