Animal Essentials Mushroom Defense Immune Support Dog & Cat Supplement, 2-fl oz bottle

$18.78 First Time Autoship Price
this order
Save 50% (up to $20) today when you set up Autoship. 

$35.68 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$37.56 Chewy Price
($18.78 /fl oz)
Save $9.39 (-20%)
$46.95 List Price
Promo, Spend $100, Get $30 eGift Card with code NEWYEAR
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

In Stock
FREE 1-3 day delivery
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • Contains a combination of three scientifically proven mushrooms (cordyceps, maitake and reishi) ) that provide antioxidants for a healthy pets immune system
  • Immune tonic can be safely used to support natural immune functions in dogs or cats
  • Premium-quality supplement help boost immune support with medicinal mushrooms
  • No preservatives, glycerin-based formulation made by experts in holistic pet care
  • Made in Phoenix, AZ at Animal Essentials’ own facility made with a balance herbal blend with a sweet flavor that appeal to most dogs and cats

Ingredient Information

Instructions

FAQ

Questions & Answers

11 Customer Questions


Is this a supplement for continued use or is it recommended for a certain amount of time?

Answer by ChewyApr 11, 2019
This supplement can be used as a preventative, given once daily in food or water to help boost your pet's immune system.

Can this be given to a dog for lymphoma the same time she is getting chemotherapy?

Answer by ChewyApr 27, 2021
Due to your pet's diagnosed condition, we recommend consulting your veterinarian to ensure this would be a good fit for your pet's current treatment plan.

Can you provide the beta glucan content for this supplement?

Answer by ChewyMay 05, 2021
Mushroom Defense contains both fruiting body and mycelium. The manufacturer does not measure for beta glucan assay but their water extraction process maximizes the beta glucan content.

does this product need to be refrigerated once the bottle has been opened? tia

Answer by ChewyApr 19, 2019
This supplement does not require refrigeration once open.

4.5
Rated 4.5 out of 5 stars
87 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Effectiveness

76% Positive

Form and Administration

78% Positive

Ingredients

80% Positive

Nutritional Value

78% Positive

51 Customer Reviews



Rated 3 out of 5 stars
By Diana on Jan 8, 2026

The bottle net weight

The bottle is advertised as 2 fl oz when it is just 1 oz for the same price as 2 fl oz. The potency of product is still there but the net weight is confusing in

The bottle is advertised as 2 fl oz when it is just 1 oz for the same price as 2 fl oz. The potency of product is still there but the net weight is confusing in Chewy.com advertising


Rated 5 out of 5 stars
By Valerie on Oct 22, 2025

It seems to be good for her health

I have been giving this Mushroom Defense to my dog since I rescued her and it seems to be keeping her healthy, so I will continue. She is now 8, and I adopted her

I have been giving this Mushroom Defense to my dog since I rescued her and it seems to be keeping her healthy, so I will continue. She is now 8, and I adopted her at 9 mos.


Rated 5 out of 5 stars
By Steven on Sep 11, 2025

I’ve used Animal essential products before

My 14-year-old dog is starting to get limpomas as I’m trying to reverse the problem a little bit by using this product. Hopefully it’ll work.

My 14-year-old dog is starting to get limpomas as I’m trying to reverse the problem a little bit by using this product. Hopefully it’ll work.


Rated 5 out of 5 stars
By Christine on Sep 11, 2025

Quality ingredients

Still waiting to see the actual results of giving this supplement, but the quality of the ingredients seems great!

Still waiting to see the actual results of giving this supplement, but the quality of the ingredients seems great!


Rated 4 out of 5 stars
By Greg on Apr 24, 2025

Please improve dropper markings

The premise of this product is great: provide the benefits of mushroom extracts to improve the health and (hopefully) longevity of your pup: "Contains a combination

The premise of this product is great: provide the benefits of mushroom extracts to improve the health and (hopefully) longevity of your pup: "Contains a combination of three scientifically proven mushrooms (cordyceps, maitake and reishi) that provide antioxidants for a healthy pets immune system." My only issue is the design of the dropper. It is a clear tube marked with embossed circles and dose gradations. But since the liquid formula is a rather dark brown, I found it very difficult to see the markings. An improvement to consider would be to make the markings stand out with a contrasting color.


Rated 5 out of 5 stars
By Tracy on Jun 6, 2025

Cancer Support

This is amazing. We are using it in conjunction with Ellie's chemo. All the dogs were jealous so we just let everyone have the mushrooms

This is amazing. We are using it in conjunction with Ellie's chemo. All the dogs were jealous so we just let everyone have the mushrooms


Rated 2 out of 5 stars
By Billie on Jul 18, 2025

Easy to use

I am trying to shrink a tumor on her tail has not worked any suggestions

I am trying to shrink a tumor on her tail has not worked any suggestions


Rated 3 out of 5 stars
By Candice on Dec 14, 2024

Not what I hoped for

So I was hoping this could help my old pup. He has medical issues. Liver enzymes high, epilepsy, and arthritis along with a back injury. I noticed it actually seemed

So I was hoping this could help my old pup. He has medical issues. Liver enzymes high, epilepsy, and arthritis along with a back injury. I noticed it actually seemed to help his arthritis but it makes his seizures worse if he has even half the recommended dosage


Rated 2 out of 5 stars
By Morgan on Dec 16, 2024

not what I needed

I needed turkeytail for my cat and this does not include it, not sure why it would only have other mushrooms when turkeytail is one of the main beneficial ones

I needed turkeytail for my cat and this does not include it, not sure why it would only have other mushrooms when turkeytail is one of the main beneficial ones. This also runs out very fast


Rated 5 out of 5 stars
By MsRB on Oct 27, 2024

It Helps!

I felt I should leave a review here to help other cat parents. I have been using the Mushroom Defense for over 2 years now for my cat who has Stomatitis & allergy

I felt I should leave a review here to help other cat parents. I have been using the Mushroom Defense for over 2 years now for my cat who has Stomatitis & allergy issues. I put 5 drops in with his wet food & he eats it right up. I have noticed an improvement with his ailments, & I will continue to use this tincture because of the positive results. I feel it definitely has been helpful for him, in building up a stronger Immune System, easing his Stomatitis, & has reduced his allergy flare-ups. I understand that not all cats are the same in how they will react to a supplement, but it is worth a try if yours has similar Immune System issues.