Bundle: Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Mousse, 5.1-oz bottle + Dog & Cat Shampoo, 16.9-oz bottle

Skip image gallery
Slide 1 of 10
$40.28 First Time Autoship Price
this order
Save 35% (up to $20) today when you set up Autoship. 
$57.27 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$60.28 Chewy Price
Save $6.70 (-10%)
$66.98 List Price
Promo, Spend $100, Get $30 eGift Card with code NEWYEAR
In Stock
FREE 1-3 day delivery
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • Mousse soothes, cleans and strengthens irritated skin for dogs.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.
  • Shampoo soothes, cleans and strengthens irritated skin for dogs and cats.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.

Dermatological Treatment for Skin Issues

Developed with veterinary dermatologists, Douxo S3 offers expert solutions for pets with skin issues. The range includes shampoos, mousses, and pads—designed for daily use and to meet specific skin needs.

Made to Manage Common Skin Conditions

Douxo S3 is made to help manage common skin conditions like allergies, yeast or bacterial overgrowth, and seborrhea. Free from sulfates, parabens, colorants, and silicones, it’s pH-adjusted, soap-free, and hypoallergenic.

Featuring High-Performing Ingredients

 All Douxo S3 formulas contain Ophytrium, a natural-origin, triple-action ingredient that soothes, rebalances and strengthens the skin barrier. Other high-quality ingredients are selected to provide specific benefits in each formula. 

Easy Care for Pleasant Moments

Douxo S3 is designed to make every routine more pleasant for pets and people, with delightful textures and scents and ergonomic packaging. Co-developed with pet parents, it offers a complete skincare solution that’s easy and enjoyable to use.

About Douxo

Backed by 20+ years of expertise in veterinary dermatology, Douxo is designed to make grooming a better experience for both you and your pets.            

Shop Douxo

Questions & Answers

1 Customer Questions

Is this good for yeast in-between dogs paws?

Answer by Chewy • Feb 13, 2024
This specially-formulated mousse contains antibacterial and antifungal ingredients that can help with yeasty paws.
Reviews
Write a Review
4.8
Rated 4.8 out of 5 stars
150 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Cleaning Power

86% Positive

Moisturizing Properties

95% Positive

Natural Ingredients

95% Positive

Scent

92% Positive

62 Customer Reviews

Rated 5 out of 5 stars
By Celeste on Jan 6, 2026

Very effective dog shampoo

I bathe my dog every so often, especially when he gets the itchy scratchies, and this shampoo effectively relieves itching and leaves his fur soft and shiny. Easy

I bathe my dog every so often, especially when he gets the itchy scratchies, and this shampoo effectively relieves itching and leaves his fur soft and shiny. Easy lather and rinse.

Rated 5 out of 5 stars
By Debra on Jul 18, 2025

Recommend by our Vet

Our English Springer Spaniel had a few areas on his hind quarters that were losing hair and looked like it might dermatitis. The Vet confirmed it was from yeast,

Our English Springer Spaniel had a few areas on his hind quarters that were losing hair and looked like it might dermatitis. The Vet confirmed it was from yeast, this type of dog is prone to it. The Vet recommended this mousse’ and the shampoo bundle., I have bathed our dog and used the mousse’ and it has eliminated the yeast and his hair has grown back in the areas where his hair loss was.

Rated 5 out of 5 stars
By Ada on Jun 23, 2025

Noticeable difference after 6 months of use

We've been using this for six months, and it's made a noticeable difference in our Schnauzer's stained paws. Our vet said the discoloration was from allergies and

We've been using this for six months, and it's made a noticeable difference in our Schnauzer's stained paws. Our vet said the discoloration was from allergies and porphyrin in his saliva. Since we can’t stop him from licking his paws, we started washing them with Douxo S3 shampoo after every walk. In the beginning, it did leave his paws a bit dry, but over time that went away.

Rated 5 out of 5 stars
By Kim on Aug 15, 2025

Effective

My vet recommended the shampoo and mousse for my standard poodle's skin issues. Since using both products, my poodle has had less itching and less dry, flaking

My vet recommended the shampoo and mousse for my standard poodle's skin issues. Since using both products, my poodle has had less itching and less dry, flaking skin.

Rated 1 out of 5 stars
By William on Jan 6, 2026

Itchy dog

This product dies not work.

This product dies not work.

Rated 5 out of 5 stars
By Nick on Dec 26, 2025

DOUXO for skin issues

Works well for skin problems

Works well for skin problems

Rated 5 out of 5 stars
By LHL on Mar 17, 2025

This Stuff Works!

My miniature schnauzer was constantly licking her paws and legs, causing her to smell horrible. My daughter did some research on Reddit and saw that there were a

My miniature schnauzer was constantly licking her paws and legs, causing her to smell horrible. My daughter did some research on Reddit and saw that there were a lot of postings about this product, so I decided to buy the shampoo and the mousse. After one washing, my dog stopped licking! I was amazed. (I don't think she likes having to stand in the sink for 10 minutes, though, but it's the price we have to pay!) The directions say it may need to be reapplied every few days until the condition gets under control. I have done that, and she doesn't seem to be licking anymore. I use the mouse for spot treatments in between baths, which are longer in between. Plus, this has a very nice smell. I'm glad I found this product. I'm a believer!

Rated 5 out of 5 stars
By Blair on Jun 26, 2025

Works!

I started noticing a difference the next day. The mousse is very convenient and the shampoo is great. Really helped my olde English Bulldogge.

I started noticing a difference the next day. The mousse is very convenient and the shampoo is great. Really helped my olde English Bulldogge.

Rated 5 out of 5 stars
By Justina on Jun 17, 2025

Good product

Our dogs very sensitive to most of the products. One of the dogs has autoimmune problems, this shampoo and foam very gentle and effective on the skin.

Our dogs very sensitive to most of the products. One of the dogs has autoimmune problems, this shampoo and foam very gentle and effective on the skin.

Rated 5 out of 5 stars
By Cecily on Oct 31, 2025

It works!

Calm itching and reduce redness.

Calm itching and reduce redness.