Epizyme Powder for Dogs & Cats, slide 1 of 1

Epizyme Powder for Dogs & Cats

Prescription Item

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Size: 12-oz
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Description

Epizyme is a prescription powder that acts as a digestive aid. This medication is most commonly used in those who are not able to properly digest food due to the lack of digestive enzymes created by the pancreas—a condition known as exocrine pancreatic insufficiency (EPI). Epizyme helps to improve the digestion of proteins, carbohydrates and fats, while also helping your pet get to a healthy weight.

Uses

Epizyme Powder helps to manage symptoms of insufficient digestion by improving your pet's ability to utilize foods to get back to a healthy weight.

Possible Side Effects

Please contact your veterinarian if the following adverse reactions occur: allergic reactions, such as difficulty breathing, swelling of the lips, tongue or face, hives, diarrhea or loose stools.

Drug & Food Interactions

Advise your veterinarian if the pet is being given antacids, such as Maalox, H2 blockers, such as cimetidine or proton pump inhibitors, such as Prilosec. Drugs other than those listed may also interact with Epizyme. Speak to your veterinarian or pharmacist before giving any prescription or over the counter medicines.

Precautions

In case of allergic reaction, administer epinephrine.

  1. Prescribing Information

See all items by Epizyme

  • Item Number
    146662
  • For Use With
    Dogs & Cats
  • Generic Name
    Pancreatic Enzyme Concentrate
  • Common Brand Name(s)
    Epizyme Powder
  • Administration Form
    Oral
  • Product Form
    Powder
  • Health Condition
    Liver Disease, Pancreatic Insufficiency Disorder (PID)
  • Drug Type
    Enzyme
Ingredients
Ingredients

Lipase, Protease, Amylase.

Instructions
Recommended Dosage

Give Epizyme Powder exactly as directed by your veterinarian. The recommended powder dosage is: Dogs 3/4 -1 teaspoonful for adult dogs with each meal Cats- 1/4 - 3/4 teaspoonful for adult cats with each meal.

Storage Instructions

Store in a tight, light-resistant, childproof container in a cool, dry location. Keep out of reach of children and pets.

FAQ

What is Epizyme Powder?

Epizyme is an enzymatic concentrate derived from porcine pancrease containing standardized lipase, protease amylase plus esterase, peptidases, nucleases and elastase.

What are the benefits of Epizyme Powder?

  • Helps improves digestion of proteins, carbohydrates and fats in pets with pancreatic insufficiency.
  • Easy to administer at meal time.
  • Helps return pets to a healthy weight, since weight loss is common when the pancreas isn't functioning properly.

How is this medication given?

Give Epizyme Powder exactly as directed by your veterinarian. The recommended powder dosage is:

Dogs- ¾-1 teaspoonful for adult dogs with each meal. Cats- ¼-3/4 teaspoonful with each meal.

How does this medication work?

Epizyme is used as a replacement therapy substituting enzymes normally produced by the pancreas that are needed to help digest and absorb fats, proteins, and carbohydrates. In pancreatic insufficiency, these enzymes are not produced in sufficient quantity.

What results can I expect?

Your pet's digestion will improve immediately, though it may take some time for your pet's weight, stools, hair coat, etc. to return to normal. In most cases, Epizyme needs to be given for the life of your pet.

Rating: 4.5 of 5 stars 2 Reviews 2 Reviews 4.5 out of 5 Stars

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100% of reviewersrecommend this product

Rating: 4.5 of 5 stars 4.5 / 5

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2 Reviews

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  • 4 out of 5 stars

    This saved my dogs life

    By on

    This medicine saved my dogs life when diagnosed with EPI. It took 6 months to finally find a vet that figured out what was wrong with him and he was so thin and malnourished I wasn't sure if he was going to make it. Within 1 day of adding Epizyme to his food his stools firmed up and he started to gain weight right away. He is now 49 pounds and thriving. I give this a 4 star because of a few reasons. One it can cause ulcers in the mouth and my dog started to get redness around his gums and teeth cracking. The medication states to let it sit for 10 mins but after doing extensive research I found out it is best to thoroughly stir in the powder with water and let sit for 30 mins before feeding making This medicine saved my dogs life when diagnosed with EPI. It took 6 months to finally find a vet that figured out what was wrong with him and he was so thin and malnourished I wasn't sure if he was going to make it. Within 1 day of adding Epizyme to his food his stools firmed up and he started to gain weight right away. He is now 49 pounds and thriving. I give this a 4 star because of a few reasons. One it can cause ulcers in the mouth and my dog started to get redness around his gums and teeth cracking. The medication states to let it sit for 10 mins but after doing extensive research I found out it is best to thoroughly stir in the powder with water and let sit for 30 mins before feeding making sure all food is coated and that you can not see any of the powder. This helped and my dogs gums are not red anymore but I am still concerned about his cracked teeth. This could not be from the medication but malnutrition from him being sick but not sure. Wish the vet would have told me about this so I could have known to let the medication sit. Second issue is that after about a month and a half the medication seems to loose its effectiveness and I read about this recently that this is a common issue with Epizyme. The first time it happened I thought It was because I was traveling a lot and the heat of the medication being in my car might have damaged the enzymes. So now when I travel with it I put it in a lunch bag with an ice pack and now a month and a half later my dogs stools are getting a little mushy and not as firm as they should be. This medication is so expensive and I buy the bigger bottles because it is more affordable this way but now I have had to throw 2 bottles that were 1/2 full away. It is hard to find information on what temps this medication should be stored at but I did finally find a source that said between 50 to 77 degrees. My house stays about 79-80 degrees and I have been struggling with how to store this in a cooler place. You can't put it in the fridge and I can't afford to keep my AC running 24-7 AT 75 degrees. I have done a lot of research on alternative enzymes and going to give Pan-tenex a try. Hope this information helps anyone with a dog that has EPI and can help them avoid some of the stuff I had to learn the hard way. … more

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  • 5 out of 5 stars

    pancreatitus enzyme powder

    By on

    I have a poodle mix that the vet put her on pancreved powder after a pancreatitis episode. I looked online and found epizyme and it had the same ingredients but was more reasonable in price. My girl has been on it for several weeks and is doing great. The only thing that would help would be a 1 tsp scoop that had a long handle. To make scooping it out easier.

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