Equioxx (Firocoxib) Tablets for Horses, 57 mg, 1 Tablet

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Keeping your horse’s bones and joints healthy is a key ingredient in keeping her happy and healthy, and if she has osteoarthritis, it is an even bigger priority for you. Equioxx Tablets for Horses is an easy-to-administer oral tablet that works to help relieve the pain and inflammation caused by your horse’s osteoarthritis. Free of steroids, Equioxx Tablets for Horses offer a safe and effective way for you to help keep your equine friend feeling fit as a filly.


EQUIOXX (firocoxib) is approved to control pain and inflammation associated with osteoarthritis (degenerative joint disease) in horses.

Possible Side Effects

The most common side effects associated with EQUIOXX (firocoxib) therapy involve the tongue, lips and skin of the mouth and face (erosions and ulcers of the mucosa and skin) and the kidney. Gastrointestinal, kidney and liver problems have also been reported with other NSAIDs.

Drug & Food Interactions

Pease consult with your veterinarian for any Food and Drug interaction concerns.


Horses should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. Treatment with EQUIOXX (firocoxib) should be terminated if signs such as inappetance, colic, abnormal feces, or lethargy are observed. See package insert for full information.

  1. Package Insert

See all items by Equioxx

  • Item Number
  • Administration Form
  • For Use With
  • Generic Name
  • Brand
    Boehringer Ingelheim
  • Product Form
  • Health Condition
    Cushing's Disease


Recommended Dosage

EQUIOXX (firocoxib) Oral Paste or EQUIOXX Tablets can be used at a dosage of 0.045 mg/lb (0.1 mg/kg) body weight for up to 14 days of treatment. EQUIOXX Oral Paste: Each marking on the syringe will treat 250 lbs of body weight, and each notch corresponds to approximately a 50 lb weight increment. To deliver the correct dose, round the horses body weight up to the nearest 50 lb increment (if the body weight is an exact 50 lb increment, do not round up). 1) While holding plunger, turn the knurled ring on the plunger to the left and slide the knurled ring along the plunger shaft so that the side nearest the barrel is at the appropriate 50 lb weight notch, aligning the arrow on the plunger with the notch on the ring. 2) Lock the ring in place by making turns to the right. Ensure it is locked (it should no longer slide) EQUIOXX Tablets: The recommended dosage of EQUIOXX Tablets is one 57 mg tablet, for oral administration in horses weighing 800-1300 lbs, once daily for up to 14 days. The overall duration of treatment with any firocoxib formulation in horses, including EQUIOXX Oral Paste or Tablets will be dependent on the response observed, but should not exceed 14 days. EQUIOXX may be given with or without food. Please see package insert for additional information.

Storage Instructions

Room Temperature 20-25C


What is an NSAID?

NSAID stands for Non-Steroidal Anti-Inflammatory Drug. NSAIDs are primarily used to treat inflammation and mild to moderate pain.

What makes EQUIOXX different than other NSAIDs?

EQUIOXX is the first non-steroidal anti-inflammatory drug (NSAID) of the coxib class used to control pain and inflammation associated with osteoarthritis in horses that has been approved for use in the U.S. As a coxib class NSAID, EQUIOXX targets COX-2 (cyclooxygenase-2), which helps generate chemicals called prostaglandins that are responsible for pain and inflammation, while sparing COX-1 (cyclooxygenase-1), which helps maintain normal bodily functions such as blood flow to the kidneys and gastric mucosal protection.

Most NSAIDs currently approved for use in horses inhibit both COX-1 and COX-2. Firocoxib, the active ingredient in EQUIOXX Brand Products is a highly selective inhibitor of COX-2.

What do I do in case my horse receives more than the prescribed amount of EQUIOXX?

Consult your veterinarian if your horse receives more than the prescribed amount of EQUIOXX.

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