Giant Breeds

Protect your dog against the scourge of heartworms with preventative heartworm medicine. Chewy carries many types of heartworm medication for dogs, including heartworm pills, topical heartworm medications, and combination products that kill other parasites too. 

Your vet is the person to ask about the best heartworm prevention for dogs. Your vet should be up to date on all the latest products available and can advise you on which ones may be best for your pup. For owners of younger dogs, it is important to ask about heartworm medicine for puppies, as younger pups need protection as well. Heartworm medication is available only by prescription, and your vet will need to perform a heartworm test before prescribing any preventatives. If your dog tests positive for heartworms, he will need to undergo heartworm treatment to eliminate the dangerous parasites. 

Once your dog has tested negative for heartworms or completed heartworm treatment, he can begin the heartworm preventative regimen recommended and prescribed by his vet. You should have the option of choosing between oral heartworm medications in pill, chewable tablet or soft chew form or a heartworm preventative medicine applied as a topical. Most heartworm medicines provide protection for up to a month, and some are available as combo treatments that protect against roundworms, hookworms, tapeworms and more.

You can also choose combination products that combine heartworm medicine with prescription [flea & tick medication](https://www.chewy.com/b/flea-tick-11563) in one easy dose for convenience. There are many options for heartworm protection and choosing the right one is important. The [Chewy pet pharmacy](https://www.chewy.com/b/pharmacy-2515) has many medications needed to keep your pets healthy and safe, including [prescription dog medicine](https://www.chewy.com/b/dog-pharmacy-11561) for a variety of ailments, [flea & tick medication for cats](https://www.chewy.com/b/flea-tick-11591) and medications for your other pets too. Shop our wide selection of heartworm medicine so you can protect your best friend 24/7.

Get dog heartworm medicine prescriptions online at Chewy Pharmacy by visiting your vet and talking about the different options. Your vet can perform a heartworm test, recommend a product and issue a prescription for the right preventative and dose. Then, go to Chewy.com and add the prescribed product to your cart. At checkout, you can add your dog’s info and vet contact information so Chewy can verify the prescription. That’s all you need to do to order your heartworm medications from Chewy!

How do I get dog heartworm medicine prescriptions online at Chewy Pharmacy?

The best prescription heartworm medicine will provide year-round protection in an easy-to-administer formula. Your vet can advise you on the different options available and issue a prescription you can use to order your medicine online. Discuss whether you want just heartworm prevention or a combination product that includes dewormers, flea and tick protection, or all three in one dose. Popular brands include Heartgard, Tri-Heart Plus, Sentinel, Revolution and Interceptor Plus.

What prescription dog heartworm medicine is best?

Dog heartworm medicine is only available with a prescription because your dog needs a heartworm test to ensure he isn’t already infected first. Giving a heartworm preventative to a dog who is already infected can be dangerous or even deadly. A vet can also determine the right dosage for your pet and suggest the right products for your dog’s lifestyle, health and age.

Why is dog heartworm medicine only available with a prescription?

Dogs need heartworm medicine in the winter, spring, fall and summer because the danger of failing to protect them is too great. Although there are fewer mosquitos around during winter in most climates, there is still the risk of a bite and heartworm contraction. Protect your best friend year-round from heartworms for safety and peace of mind.

Do dogs need heartworm medicine in the winter?

Set up Autoship for your prescription dog heartworm medicine by selecting the Autoship option and choosing a delivery frequency at checkout. Once you set up Autoship, you can change or cancel it any time you want. You must have a valid prescription or remaining refills on file for Autoship pharmacy deliveries to occur. If we do not have a prescription, or if your prescription is expiring soon, one of our team members will reach out to your vet to obtain all the necessary information. You can always have your dog’s heartworm medicine on hand with Autoship from Chewy!

How do I set up Autoship for my prescription dog heartworm medicine?

Heartworm

Prescription Heartworm Prevention Medicine for Dogs

Heartworm Medicine for Giant Dogs

BreedSize

Shop Chewy for the best deals on Heartworm Medicine for Giant Dogs and more with fast free shipping, low prices, and award-winning customer service. Read ratings and reviews so you can find the right Heartworm Medicine for Giant Dogs for your pet.

Heartworm Medicine for Giant Dogs (Free Shipping) | Chewy

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Autoship & Save Eligible

Extra Small & Toy Breeds

Small Breeds

Medium Breeds

Large Breeds

Breed Size

Ear Mites

Fleas

Heartworms

Hookworms

Mange

Roundworms

Tapeworms

Ticks

Whipworms

Health Condition

Credelio

Elanco

Interceptor Plus

Iverhart Max

Revolt

Simparica Trio

Virbac

Zoetis

Brand

[30,39.99]

[50,*]

Price

[4,5]

[3,5]

[2,5]

[1,5]

Customer Rating

Interceptor Plus for Dogs, 6 Chews (6-mos. supply) & Credelio for Dogs, 6 Chewable Tablets (6-mos. supply)

Interceptor Plus Chew for Dogs, 50.1-100 lbs, (Blue Box), 6 Chews (6-mos. supply) & Credelio Chewable Tablet for Dogs, 25.1-50 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)

Heartworm Medicine for Giant Dogs

Bundle: Interceptor Plus Chew for Dogs, 50.1-100 lbs, (Blue Box), 6 Chews (6-mos. supply) & Cre...

Simparica Trio Chewable Tablet for Dogs, 88.1-132.0 lbs, (Brown Box), 6 Chewable Tablets (6-mos...

Revolt Topical Solution for Dogs, 85.1-130 lbs, (Plum Box), 6 Doses (6-mos. supply)

Iverhart Max Chew for Dogs, 50.1-100 lbs, (Brown Box), 6 Chews (6-mos. supply)

Breed Size

Health Condition

Brand

Price

Customer Rating