Nature's Miracle Oxy Formula Set-In Dog Stain Destroyer, 1-gal bottle

Deal
Skip image gallery
Slide 1 of 12

$13.57 First Time Autoship Price
this order
Save 35% on your first Autoship order. 
$19.84 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$20.88 Chewy Price
($20.88 /gl)
Save $15.11 (-42%)
$35.99 List Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
Promo, Buy 3, Get 4th Free- Mix & Match
In Stock
FREE 1-3 day delivery on first-time orders over $35
Free 365-day returns

About This Item

Details

  • Great for use on deep-set stains and severe, old, or stubborn odors.
  • Features a refreshing scent to get your home smelling clean again.
  • The oxygen concentrate works to penetrate, separate, and lift embedded stains and odors.
  • Nature’s Miracle bottles are designed with 25% post-consumer recycled material.
  • Safe for use around your pets and home when used and stored as directed.

Instructions

Learn More About Nature's Miracle From Our Team of Experts

Related to This Item

About Nature's Miracle Stain and Odor Solutions

Trust the Miracle

Nature’s Miracle pet stain and odor removers have been a trusted choice for pet mess cleanup for over 40 years. When your pets make not-so-cute messes, you can always rely on Nature’s Miracle products to get the job done.

Solutions for the Toughest Pet Messes

Nature’s Miracle stain and odor formulas help you tackle tough pet messes like urine, feces, vomit and drool. From spot-cleaning everyday messes to eliminating stubborn stains, these solutions help you keep your home clean.

Break Down Stains on Contact

Nature’s Miracle cleaning formulas start to work the moment they come in contact with pet messes. With several targeted cleanup solutions available, you’ll find it easy to choose just the right product for your needs.

Not All Pet Messes Are the Same

Solutions for Dogs

Nature’s Miracle products for dogs are specially formulated to handle your dog’s messes. Choose from a variety of formulas tailor made to handle any canine stain or odor removal jobs that come your way.

Solutions for Cats

Cat messes and odors present their own unique challenges, and Nature’s Miracle products for cats are specially formulated to tackle them. From Urine Destroyer to enzymatic Stain & Odor Remover formulas, these products are made to get the job done.

Targeted Solutions for Life With Pets

Original Stain & Odor

The original, must-have formula made for cleaning up everyday pet messes.

Simply Nature’s Miracle

Made with 86% plant-based surfactants and essential oils for fragrance, you can feel good about using these in your home.

Urine Destroyer

These targeted formulas are made to destroy severe urine stains and odors and get rid of yellow, sticky residue.

Advanced Eliminators

Use these advanced bio-enzymatic and antibacterial formulas to eliminate the most severe pet messes.

Sprays and Gallon Sizes

Choose from a range of convenient sprays to have on hand for targeted cleanup on a variety of surfaces. The easy-to-store gallon jugs are great for refills and perfect for multi-pet homes, too.

Easy Pour

Get the right amount of solution right where you need it with this easy-pour bottle and spout.

Aerosol Foam

Penetrating aerosol foam gets deep down into carpet fibers to power out severe pet messes.

About Nature's Miracle

Cat messes and odors present their own unique challenges, and Nature’s Miracle litter box products for cats are specially formulated to tackle them. Make life with your cat a little more pleasant with these trusted litter box solutions!

Shop Nature's Miracle

Compare Similar Items

Nature's Miracle
Oxy Formula Set-In Dog Stain Destroyer, 1-gal bottle
Nature's Miracle
Oxy Formula Set-In Dog Stain Destroyer, 1-gal bottle
$20.88 Chewy Price
($20.88/gl)
Rated 4.4 out of 5 stars
541Reviews
Nature's Miracle
Odor Control Formula Dog Stain & Odor Remover, 1-gal bottle
Nature's Miracle
Odor Control Formula Dog Stain & Odor Remover, 1-gal bottle
$24.97 Chewy Price
($24.97/gl)
Rated 4.7 out of 5 stars
1.8KReviews
Simple Green
Bio Dog Stain & Odor Remover, 1-gal jug
Simple Green
Bio Dog Stain & Odor Remover, 1-gal jug
$19.99 Chewy Price
($19.99/gl)
Rated 4.6 out of 5 stars
122Reviews
KIDS 'N' PETS
Instant All Purpose Stain & Odor Remover, 1-gal
KIDS 'N' PETS
Instant All Purpose Stain & Odor Remover, 1-gal
$20.75 Chewy Price
($20.75/gl)
Rated 4.7 out of 5 stars
190Reviews
Ion Fusion
Professional ION Formula Cool Cucumber Pet Stain & Odor Destroyer, 1-gallon bottle
Ion Fusion
Professional ION Formula Cool Cucumber Pet Stain & Odor Destroyer, 1-gallon bottle
$28.99 Chewy Price
($28.99/gl)
Rated 5 out of 5 stars
1Review
Nature's Miracle
Enzymatic Formula Advanced Dog Stain & Odor Eliminator, 32-fl oz bottle, Fresh Scen...
Nature's Miracle
Enzymatic Formula Advanced Dog Stain & Odor Eliminator, 32-fl oz bottle, Fresh Scen...
$13.57 Chewy Price
($0.43/fl oz)
Rated 4.6 out of 5 stars
1.1KReviews
Nature's Miracle
Enzymatic Formula Advanced Stain & Odor Eliminator, 32-fl oz bottle, Sunny Lemon Sc...
Nature's Miracle
Enzymatic Formula Advanced Stain & Odor Eliminator, 32-fl oz bottle, Sunny Lemon Sc...
$13.57 Chewy Price
($0.43/fl oz)
Rated 4.5 out of 5 stars
110Reviews
Urine Off
Dog & Puppy Formula Stain & Odor Remover, 32-fl oz bottle
Urine Off
Dog & Puppy Formula Stain & Odor Remover, 32-fl oz bottle
$17.99 Chewy Price
($0.57/fl oz)
Rated 4.4 out of 5 stars
37Reviews
Paw Inspired
Professional Dog Stain & Odor Eliminator Spray, 32-fl oz bottle
Paw Inspired
Professional Dog Stain & Odor Eliminator Spray, 32-fl oz bottle
$17.88 Chewy Price
($0.56/fl oz)
Rated 4.9 out of 5 stars
12Reviews
Nature's Miracle
Dog Enzymatic Stain Remover & Odor Eliminator, Melon Burst Scent, 32-fl oz bottle
Nature's Miracle
Dog Enzymatic Stain Remover & Odor Eliminator, Melon Burst Scent, 32-fl oz bottle
$13.88 Chewy Price
($0.44/fl oz)
Rated 4.7 out of 5 stars
156Reviews
Simple Solution
Extreme Stain & Odor Remover, 32-fl oz bottle
Simple Solution
Extreme Stain & Odor Remover, 32-fl oz bottle
$11.41 Chewy Price
($0.36/fl oz)
Rated 4.5 out of 5 stars
325Reviews
Nature's Miracle
Advanced Platinum Dog Stain & Odor Remover & Virus Disinfectant, 32-fl oz bottle
Nature's Miracle
Advanced Platinum Dog Stain & Odor Remover & Virus Disinfectant, 32-fl oz bottle
$14.79 Chewy Price
($0.47/fl oz)
Rated 4.7 out of 5 stars
97Reviews
Ingredients           
—
Water, C9-11 Ethoxylated Alcohols, Fragrance, Microbial Mixture, Preservative, Pentasodium Triphosphate, Sodium Xylene Sulfonate, Citric Acid,
Water, Sodium Dodecyl Sulfate, Modified Polymer, Sodium Saccharin, Bacillus Amyloliquefaciens, Bacillus Subtilis, Bacillus Pumilus, Bacillus
Purified Water, Sodium Tripolyphosphate, Glycerin, Isopropyl Alcohol, Ordenone, Alcohol Ethoxylate, Protease, Lipase, Alpha-Amylase, Fragrance,
Water, Isopropylidene Glycol, IONs, MGDA Sodium Salt, Sodium Citrate, Cucumber Essence, Cucumber C3.
—
Water, C9-11 Ethoxylated Alcohols, Fragrance, Microbial Mixture, Preservative, Polyethylene Glycol Monoundecyl Ether, Pentasodium Triphosphate, Sodium
Water, Naturally-Derived Cleanser, Non-Pathogenic Bacteria Blend, Fragrance, Preservatives, Opacifier, Anti-Foam Emulsion
Water, Advanced Biological Blend, Non-Ionic Surficant, Franrance, Odor Counteractant, Opacifier
—
Purified water, natural non-pathogenic bacteria, denatured ethanol, natural enzymes, detergent and fragrance
Chlorine Dioxide, Alkyl (60% C14, 30% C16, 5% C12, 5% C18) Dimethyl Benzyl Ammonium Chloride, Alkyl (68% C12, 32% C14) Dimethyl Ethylbenzyl Ammonium
Cleaner Usage           
Carpet, Hard Surface, Clothing/Laundry, Bedding, Furniture/Upholstery
Carpet, Bedding, Furniture/Upholstery
Litter Box, Fabric, Carpet, Hard Surface, Carpet Machine, Kennels, Bedding, Furniture/Upholstery, Hardwood Floor
Litter Box, Fabric, Carpet, Hard Surface, Car, Carpet Machine, Clothing/Laundry, Kennels, Furniture/Upholstery
Carpet, Hard Surface
Fabric, Hard Surface
Fabric, Carpet, Hard Surface, Furniture/Upholstery
Carpet, Bedding, Furniture/Upholstery
Carpet, Bedding, Furniture/Upholstery
Carpet, Bedding, Furniture/Upholstery
Fabric, Carpet, Hard Surface, Furniture/Upholstery
Carpet, Bedding, Furniture/Upholstery
Lifestage           
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
Puppy
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
Cleaner Type           
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Stain Remover
Stain Remover
Deodorizer, Stain Remover
Deodorizer, Stain Remover
Stain Remover

Frequently bought together

Questions & Answers

29 Customer Questions

Is this ok to use on hardwood floors?

Answer by Chewy • Apr 01, 2018
This product is not recommended for use on hardwood floors. It's meant to be used on carpets, clothing, upholstery. blankets, and pet bedding.

Someone left a cat in a house for a month moved out and now the house smells of cat urine. How do you get the smell gone with out tearing out the carpet and subfloors

Answer by Chewy • Dec 25, 2018
To eliminate odors thoroughly soak the entire area with Nature’s Miracle Stain and Odor Remover. For carpets, apply enough to reach the urine penetration in the pad and floor. This may mean lifting the carpet and applying directly to the pad and floor. Allow the product to air dry. Depending on air circulation, carpets and upholstery may take up to 2 weeks to dry completely. If after 2 weeks there is still an odor, Nature’s Miracle Stain and Odor Remover has not reached ALL of the odor-causing material. Pinpoint odor source and repeat cleaning process. Keep the product away from children and pets and do not allow pets onto the treated area until it is completely dried.

To repeat an earlier question that was not answered, Is this an enzyme cleaner??

Answer by Chewy • Oct 02, 2020
This is not an enzymatic formula. This product uses an oxygen concentrate to lift and remove deep-set stains. The Nature's Miracle Urine Destroyer is an enzymatic formula that works best for urine stains and odors.

can i mop with it

Answer by Chewy • Apr 08, 2018
The Oxy Pet Stain and Odor Remover is not intended to be mopped with but sprayed and wiped up with a cloth.
Reviews
Write a Review
4.4
Rated 4.4 out of 5 stars
541 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

87% Positive

Effectiveness

90% Positive

Safety

90% Positive

Stain Type

87% Positive

358 Customer Reviews

Rated 5 out of 5 stars
By Irene on Sep 29, 2025

It WORKS

Ive tried to many, more expensive products, and nothing has ever completely worked. This stuff works quickly! On fresh stains, it completely removes the odor and

Ive tried to many, more expensive products, and nothing has ever completely worked. This stuff works quickly! On fresh stains, it completely removes the odor and stain. On older, set in stains, I saturate stain, let it sit, and by the next day, most if not all of the stain is gone. Sometimes, I need to do it more than once, but, it does work. It is much more affordable than others, and I keep it on hand always.

Rated 5 out of 5 stars
By James on Sep 16, 2025

Stain remover

Best pet stain remover out there I’ve tried all sorts of things but this is top spray let sit dab with a towel and repeat if necessary has never let me down

Best pet stain remover out there I’ve tried all sorts of things but this is top spray let sit dab with a towel and repeat if necessary has never let me down

Rated 5 out of 5 stars
By Barbara on Jul 13, 2025

The scent was no bad

We have a puppy that was still being house trained. The oxygen formula was used on my carpeted areas. I also used this in my washer when washing the reusable pee

We have a puppy that was still being house trained. The oxygen formula was used on my carpeted areas. I also used this in my washer when washing the reusable pee pads and other items needing to be cleaned.

Rated 3 out of 5 stars
By Kathleen on Sep 21, 2025

Almost Gone!

The formula did lighten the stain but, after several usages, the stain was still visible.

The formula did lighten the stain but, after several usages, the stain was still visible.

Rated 5 out of 5 stars
By VICKIE on Jun 30, 2025

This works!

This stuff really works in a hurry and leaves a very pleasant scent. I had uh a bad dog mark and then my dog marked over it since I use this. There has been no more

This stuff really works in a hurry and leaves a very pleasant scent. I had uh a bad dog mark and then my dog marked over it since I use this. There has been no more remarking and no odor. Good stuff.

Rated 5 out of 5 stars
By Beth on Aug 19, 2025

Works great on wool carpet

My old kitty had a bad GI problem at the end of her life and this got all the stains out of my wool rug.

My old kitty had a bad GI problem at the end of her life and this got all the stains out of my wool rug.

Rated 2 out of 5 stars
By Stef on May 25, 2025

Great product

Olny complaint is the box was soaking wet and the bottles had leaked in side seals were half on but product is great what was left in one bottle saved my dogs favorite

Olny complaint is the box was soaking wet and the bottles had leaked in side seals were half on but product is great what was left in one bottle saved my dogs favorite bed I plan to order more but going to call to see if the next 5 bottles they will extra tape lids on

Rated 5 out of 5 stars
By Patricia on Sep 5, 2025

The reviews on this product.

We have a senior cat and this product gets his throw up removed from our rug.

We have a senior cat and this product gets his throw up removed from our rug.

Rated 5 out of 5 stars
By Stephanie on Jun 30, 2025

The best...

I've tried so many different carpet cleaners for pet (and other) stains. This stuff is the best at removing all of them.

I've tried so many different carpet cleaners for pet (and other) stains. This stuff is the best at removing all of them.

Rated 5 out of 5 stars
By Kathryn on Aug 9, 2025

Perfect solution!

Product cleaned soiled areas, smelled pleasant and eliminated stains.

Product cleaned soiled areas, smelled pleasant and eliminated stains.