Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 60 count blister pack

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About This Item

Details

  • Support your dog’s liver health with veterinarian-recommended Denamarin.
  • Denamarin for dogs contains S-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione—one of the liver’s main detoxifying agents.
  • The silybin (a bioactive component of milk thistle extract) found in Denamarin is more bioavailable than standardized milk thistle extract.
  • The liver, one of your pet’s most vital organs, is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system.
  • Denamarin undergoes thorough quality inspections to ensure your dog receives a safe, high-quality product.

Ingredient Information

Instructions

FAQ

Learn More About Nutramax From Our Team of Experts

Combined Power of SAMe and Silybin

Denamarin combines the power of S-adenosylmethionine (SAMe) and silybin to help support healthy liver function in pets.

#1 Veterinarian Recommended

Denamarin is the #1 veterinarian recommended liver support brand.

*Survey conducted among small animal veterinarians who recommended liver support supplements.

The Denamarin Difference

The Silybin (a bioactive component of milk thistle extract) found in Denamarin is more bioavailable than standardized milk thistle.

Unmatched Quality

Each batch of Cosequin undergoes rigorous quality inspections, ensuring that your pet receives a high-quality joint health supplement.

About Nutramax

Family owned and operated since 1992, Nutramax Laboratories exceeds the industry standard for animal health supplements. We develop high-quality products for joint, liver, digestive health, and overall wellness.

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Questions & Answers

26 Customer Questions

When will have this medicine ?

Answer by Mildred • Jun 07, 2022
You can get the one for cats and dogs 12#. It has directions for over 12#

My girl takes denamarin, but it always came in a box, medium size canine dose. Why r they different in the bottle? Are they the same?

Answer by Huey • Aug 17, 2025
Check the ingredients and the amount of milligrams in each. Please make sure that the former medicine that came in a box is the exact ones. There is an "improved" chewable tablet. Depending on the instructions of the Vet, make sure that you are giving your pet the exact medication, as well as dosage.

Will this help decrease elevated ALT and ALP levels?

Answer by Chewy • Jun 12, 2018
Denamarin is a liver support supplement rather than a pharmaceutical product. Due to this, and the fact that every pet and it's needs is unique, Nutramax cannot guarantee efficacy.

Why is this pill blue? Is there a full list of the ingredients for the tablets? My dog has cancer and I'm trying to avoid as much artifical additives as possible.

Answer by Chewy • May 15, 2019
The pill is colored blue using an artificial dye for identification purposes. It you shave off the coloring you will have to use the tablet within 20 minutes.
Reviews
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4.6
Rated 4.6 out of 5 stars
1725 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Effectiveness

88% Positive

Form and Administration

88% Positive

Ingredients

86% Positive

Nutritional Value

84% Positive

738 Customer Reviews

Rated 5 out of 5 stars
By Amanda on Dec 31, 2025

Helped liver enzymes for our kitten with dry FIP

My daughter’s little guy Ravioli was diagnosed with dry FIP at one year old. Liver enzymes being off the charts was one of his concerns. This in conjunction with

My daughter’s little guy Ravioli was diagnosed with dry FIP at one year old. Liver enzymes being off the charts was one of his concerns. This in conjunction with vet prescribed antivirals, appetite stimulant, and sub-q fluids saved his life. At his 6 month post-diagnosis check up, everything was beautiful with liver enzymes still ever so slightly elevated. We’ve kept him on this medicine to help support his liver further and hope to be able to wean in another month or two. Grateful for this med and for chewy getting it to us promptly when we need it.

Rated 4 out of 5 stars
By Marie on Jan 15, 2026

Your Sphynx cat needs this

I’m a third time owner of a Sphynx cat. They have weak immune systems. When I stop giving my 3 year old this tablet her health declines. Only downside is the pill

I’m a third time owner of a Sphynx cat. They have weak immune systems. When I stop giving my 3 year old this tablet her health declines. Only downside is the pill is the size of an Advil. I suggest the ones in foil instead of the jar. They are light sensitive and the foil helps keep them potent They are pricy but they work. They were highly recommended by my veterinarian

Rated 3 out of 5 stars
By Tilly on Dec 20, 2025
Top 1000 Contibutor

Didn't improve my pup's ALT values and gives both pups diarrhea

My vet recommended trying this liver supplement to see if it might improve Tilly's liver values. I gave this supplement to both pups as supplements for 6 weeks

My vet recommended trying this liver supplement to see if it might improve Tilly's liver values. I gave this supplement to both pups as supplements for 6 weeks. Tilly just got her test results and her liver values continued to increase. It is possible that whatever medical condition that is causing the ALT values to go up cannot be improved with this supplement. My own concern with this supplement is that it causes both pups to have diarrhea. Recommend ordering a small quantity to see how your pups react to this supplement before buying larger quality. I originally bought 2 boxes and then more 2 bottles to have enough for Tilly's recent blood work. I have taken Lola off this supplements because her colon is so sensitive that she would get bloody stool along with diarrhea when on this supplement. I am waiting to hear from the vet if i should continue to keep Tilly on this supplement.

Rated 5 out of 5 stars
By gale on Dec 25, 2025

Coated Tablets NO BITTERNESS

Relatively easy to give to our Cat, Mr. Foot. I hold, husband puts in mouth, holds shut, blows on his face. Release him to eat treats. Same nightly routine 30 nights

Relatively easy to give to our Cat, Mr. Foot. I hold, husband puts in mouth, holds shut, blows on his face. Release him to eat treats. Same nightly routine 30 nights. No spitting tablet out, no drooling (thanks to coated tablet), tablet swallowed every night. Only blood test, 60 more days will determine effectiveness of Denamarin.

Rated 2 out of 5 stars
By Mocha on Nov 6, 2025

Dog refuses to eat it

This is supposed to be given on an empty stomach for full efficacy, but no matter how I try to hide the pill, she won't eat it. My dog is extremely food motivated--she

This is supposed to be given on an empty stomach for full efficacy, but no matter how I try to hide the pill, she won't eat it. My dog is extremely food motivated--she will eat anything and will tolerate most medications, but for whatever reason hates Denamarin. I have wrapped it in chicken, bread, banana puree, she will only eat the food substance around it and spit the pill back out. I have also tried forcing the pill down her throat with no success and I feel bad for scaring her like that :( no matter what my dog will not touch this stuff. Maybe yours will be different but I cannot vouch for the efficacy of Denamarin due to my dog's compliance issues.

Rated 5 out of 5 stars
By Nancy on Dec 20, 2025

Chewy came through

My 19 year old cat with a number of health issues had to have this to balance her liver enzymes. It saved her life. When my vet’s office had trouble getting this

My 19 year old cat with a number of health issues had to have this to balance her liver enzymes. It saved her life. When my vet’s office had trouble getting this I turned to chewy. They delivered it right away!

Rated 5 out of 5 stars
By Julie on Dec 14, 2025

This prescription is to help my kitty be cat, Miss Lola

My veterinarian recommended this product to help Lola‘s liver enzymes for when she goes in next month for lab test, her liver enzymes have gone down. Pray for my

My veterinarian recommended this product to help Lola‘s liver enzymes for when she goes in next month for lab test, her liver enzymes have gone down. Pray for my little kitty cat, Miss Lola.

Rated 5 out of 5 stars
By Kathleen on Jan 21, 2026

Liver supplement helping liver values

My older dog had some concerns about his liver values on blood work. This supplement seems to be keeping values in check.

My older dog had some concerns about his liver values on blood work. This supplement seems to be keeping values in check.

Rated 5 out of 5 stars
By Sondra on Dec 3, 2025

The patience and friendliness of order taker.

Hopefully it will eliminate the need for surgery. With liver disease It is important not to eat a lot of fat. More dried white chicken breast would be nice, need

Hopefully it will eliminate the need for surgery. With liver disease It is important not to eat a lot of fat. More dried white chicken breast would be nice, need things with low fat content.

Rated 5 out of 5 stars
By Leah on Nov 15, 2025

I love this stuff!

My cats bloodwork shows how well this along with the antibiotics saved his life! Also was giving royal canine recovery food. See the bloodwork for yourself! Absolutely

My cats bloodwork shows how well this along with the antibiotics saved his life! Also was giving royal canine recovery food. See the bloodwork for yourself! Absolutely amazing!