NUTRAMAX Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count -

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats

By Nutramax
Rated 4.468 out of 5 stars
Breed Size

$31.99Chewy Price
$30.39Autoship Price
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About This Item


  • Denamarin contains s-adenosylmethionine (SAMe) to help increase gluthione levels to support your dog and cat’s liver detoxification capabilities.
  • Silybin found in Denamarin has shown better absorption in dogs and cats than the milk thistle extract found in many other products.
  • Supporting your dog and cat’s liver health promotes the liver’s ability to remove toxins, store energy, aid digestion and support the immune system.
  • Nutramax Laboratories Veterinary Science has made supplements to support joint health, digestive health and overall wellness for over 30 years.
  • Veterinarian formulated with high-quality ingredients to ensure supplement safety.

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Nutritional Information

Feeding Instructions


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Questions & Answers

23 Customer Questions

Is the medication inside the tablet absorbed even if the outer gel rubbery tablet is still intact after in the stomach for a few hours?
Answer by SpencerSep 14, 2021
I am having the same issue with my small dog. He throws it up intact. I now put a small nick in the gel coating to make sure it dissolves.

When will have this medicine ?
Answer by MillyJun 07, 2022
You can get the one for cats and dogs 12#. It has directions for over 12#

Answer by ChewyJul 09, 2018
Overnight fast meaning not to feed your dog the night prior to treatment.

Will this help decrease elevated ALT and ALP levels?
Answer by ChewyJun 12, 2018
Denamarin is a liver support supplement rather than a pharmaceutical product. Due to this, and the fact that every pet and it's needs is unique, Nutramax cannot guarantee efficacy.

ReviewsWrite a Review

Rated 4.468 out of 5 stars
344 Ratings
Would recommend to a friend

344 Customer Reviews

Rated 5 out of 5 stars
By CatMom on Mar 27, 2023

Denamarin for Cats

I've been giving Denamarin to one of my cats for six-seven months. The only way she will take it is when it's in a Greenies Pill Pocket. The original Denamarin was scripted by an internal medicine specialist. I found thru chewy that a script is not needed. The cost savings between the specialty center and chewy was very large. I highly-recommend chewy as they are pawesome to deal with and are very knowledgeable.

Rated 5 out of 5 stars
By Robert on Mar 29, 2023

Life Saver

We took our little dog Annie to the Vet since she was acting puny after blood work while the Vet was researching further a "liver disease", I did my own research and found "Canine Milk Thistle", suggested this to the Vet who recommended Denamarin. Annie has been on the med for about 2 weeks and is showing amazing results.

Rated 5 out of 5 stars
By Nina on Apr 30, 2023


Because my dog was diagnosed with liver issues the vet started her on Denamarin. Honestly, almost an immediate change. She went from not eating to eating again and from lethargy to perky. This works!

Rated 5 out of 5 stars
By nori on Feb 13, 2023

Cat takes it.

I pill my cat orally first thing in the morning on an empty stomach and then give her the B12 by the same manufacturer as a treat. She will usually then go drink water from her fountain. This system works well for me. I then wait 30 minutes to 1hr and then give her food with one pack of immuquin, also made by this brand. Backstory: My cat's liver enzymes came back elevated at her recent bloodwork so I did my research and wanted to add supplements to help her before going for an ultrasound. I'm hoping to see good results because we are making sure she is taking these religiously. I will update the review after her bloodwork in the future.

Rated 1 out of 5 stars
By Patrice on Feb 27, 2023

The dye runs off on your fingers

I bought this for my ailing dog. (bad liver) The dark blue dye covered my fingers when I was giving it to her. Then it was on her tongue and fur on her lower mouth. I ended up only giving her 2 pills because she got very loose stool just after two pills. I'm not sure if this caused her problem but it was the only new med/food given/introduced to her and her stool became normal a day later.

Rated 5 out of 5 stars
By CatLady on May 25, 2023

Happy Chewy Had

Was so happy to see Chewy had this product! Great price compared to buying it from vet office. One happy customer here :)

Rated 1 out of 5 stars
By Deirdra on Mar 24, 2023

made my dog sick !

My dog has been on denamarin for about a month and a half . Ever since she started it she pukes at least once a day and has diarrhea. I am no longer using this product. It may work for some dogs but not all .

Rated 4 out of 5 stars
By AKPO on Jan 3, 2023

Blue Coating

We were happy to find this available on Chewy after our vet stopped offering it. The replacement from our vet was making our dog sick so we went back to the old option, Denamarin. My only complaint is the blue coating which comes off on everything. It takes a few times to get my dog to swallow her pill and in that time her white fur, my hands, and the pill shooter all become covered in bright blue residue. We didn't have this problem when we were able to get it directly from the vet so I'm not sure what the change has been.

Rated 1 out of 5 stars
By B1234 on Jan 30, 2023

Made my cat throw up

I was giving this my cat for a few days, as the vet recommended a liver supplement for him. He kept throwing up everyday. I discontinued and he has not thrown up at all. Something in this pill makes him very ill. Contacted Chewy and they refunded my money. Great customer service.

Rated 5 out of 5 stars
By Jeanne on Apr 9, 2023

Good stuff

Great supplement. Really helped with a cat who was recovering from liver issues related to inappetence