Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats

By Nutramax
Rated 4.4472 out of 5 stars

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$32.99Chewy Price
$31.34Autoship Price
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About This Item


  • Denamarin contains s-adenosylmethionine (SAMe) to help increase your pet’s glutathione levels and support his liver’s detoxification capabilities.
  • Silybin found in Denamarin has shown better absorption in dogs and cats than the milk thistle extract found in many other products.
  • Supporting your dog and cat’s liver health promotes the liver’s ability to remove toxins, store energy, aid digestion and support the immune system.
  • Nutramax Laboratories Veterinary Science has made supplements to support joint health, digestive health and overall wellness for over 30 years.
  • Veterinarian formulated with high-quality ingredients to ensure supplement safety.

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Nutritional Information

Feeding Instructions


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Top IngredientsActive Ingredients: S-Adenosylmethionine, Silybin A+B.Active Ingredients: S-Adenosylmethionine, Silybin A+B.Active Ingredients: S-Adenosylmethionine, Silybin A+B.S-Adenosylmethionine 90 mg, Silybin-phosphatidylcholine complex (SPC)* 31 mg, *Providing 9 mg of Silybin A+B....S-Adenosylmethionine.
Breed SizeExtra Small Breeds, Small BreedsSmall Breeds, Medium Breeds, Large BreedsExtra Small Breeds, Small Breeds, Medium Breeds...Small BreedsExtra Small Breeds, Small Breeds
Health FeatureLiver CareLiver CareLiver CareLiver Care, Vitamins & MineralsLiver Care
LifestageAdult, SeniorAdult, SeniorAdult, SeniorAll LifestagesAdult, Senior
Food FormSupplementSupplementSupplementSupplementSupplement

Questions & Answers

24 Customer Questions

Is the medication inside the tablet absorbed even if the outer gel rubbery tablet is still intact after in the stomach for a few hours?
Answer by SpencerSep 14, 2021
I am having the same issue with my small dog. He throws it up intact. I now put a small nick in the gel coating to make sure it dissolves.

When will have this medicine ?
Answer by MillyJun 07, 2022
You can get the one for cats and dogs 12#. It has directions for over 12#

Answer by ChewyJul 09, 2018
Overnight fast meaning not to feed your dog the night prior to treatment.

Will this help decrease elevated ALT and ALP levels?
Answer by ChewyJun 12, 2018
Denamarin is a liver support supplement rather than a pharmaceutical product. Due to this, and the fact that every pet and it's needs is unique, Nutramax cannot guarantee efficacy.

ReviewsWrite a Review

Rated 4.4472 out of 5 stars
369 Ratings
Would recommend to a friend

368 Customer Reviews

Rated 5 out of 5 stars
By Katherine on Sep 15, 2023

Nutramax To The Rescue!

I have two senior toy poodles who both need to take a liver supplement for different reasons. Denamarin was the recommended medication in both cases. They have both been on the Denamarin for several months and had good check-ups last time around...that, in itself, is reason for celebration!!!

Rated 3 out of 5 stars
By Christine on Aug 7, 2023
Top 1000 Contibutor

Made my cat throw up

I first tried giving the pills from the blister pack to my cat with liver disease. He kept throwing up the pill hours later, in tact! The company explained that the blue pills in the blister pack have a special coating which makes it more difficult to break down, and I should try the beige pills that come in the bottle instead. So, I tried the bottle and he still threw them up. I could not give these to him so I can't comment on their effectiveness. I gave three stars because I do like the company and they were very helpful in trying to solve the vomiting issues. Unfortunately, my cat could not keep them down.

Rated 4 out of 5 stars
By Vicki on Sep 16, 2023

I HOPE it's helping!

Until I get more labwork done on my cat, Aster, it really won't be possible to know how effective this is. Meanwhile, it gives me some peace of mind to know I'm doing SOMEthing for her, based on the recommendations of others.

Rated 5 out of 5 stars
By JeanneD on Jul 24, 2023

Nice to Have Confidence!

It's comforting to know that my dog's Denamarin will arrive on schedule, exactly as requested! I had a hard time finding the Denamarin in my dog's strength, even from my dog's vet! I saw that I could set this up on auto-ship with Chewy and never have to worry about finding it again. It's nice to know that my dog's liver supplement will automatically arrive. I also really like the advance notice that I get from Chewy about a week before it ships. Thanks for such great service!

Rated 5 out of 5 stars
By Charm on Aug 9, 2023

For Cats with Liver Issues

My cat has been taken Denamarin for the past 2 years. It has literally saved her life, bringing her liver readings into a normal range from the high 400's. One pill dropped into the back of her throat each day and she swallows it with no problem. As long as you have a cooperative cat I high recommend this product.

Rated 5 out of 5 stars
By NiksMum on Jul 8, 2023

Effective Product

I bought this for my puppy after discovering that he has liver shunt. Originally, his tests showed high levels for his liver enzymes and after a month of being on this medication, he tested again and his enzyme levels have decreased. We still have a journey to complete but we are hopeful that this product will assist him. He won't take the pill by itself so I give it to him with a little bit of peanut butter.

Rated 5 out of 5 stars
By STR55 on Jun 22, 2023

Vet recommended and seems to be working

My 13 yr old kitty had elevated liver enzymes and bilirubin. His ultrasound showed changes in the liver My vet recommended Denamarin I read some reviews about people having a hard time giving it to their cats. I was nervous I wouldn’t be able to get it down his throat but I put it in the back of his mouth snd just swallows it..No problem. After 2 weeks on this supplement we rechecked his blood work and everything is back to normal. I will continue to give it to him since it did help his elevated liver tests Would definitely recommend this supplement

Rated 1 out of 5 stars
By SCB on Jul 19, 2023

Nutramax Denamarin

New form of non-coated pill is more difficult to administer; new packaging is less efficient in preserving the tablet. Resulting in cost savings to manufacturer - no savings to consumers. The medication does help, but very dissatisfied with manufacturer.

Rated 5 out of 5 stars
By Laura on Jul 24, 2023

Just what the doctor ordered

One of my cats has liver issues and this supplement turned her situation around. Her latest bloodwork came back with beautiful results. Glad to be able to find this at Chewy, as it is half the cost of what the vet's office charges.

Rated 5 out of 5 stars
By Kittylover4life on Jun 20, 2023

Life Saver!

This little pill came recommended by my vet. My senior Siamese is showing huge improvement in his color and appetite. His eyes were very yellow in the corners and now they are cleared up. He takes the pill well in a Greenies Pill Pocket. He is eating like a mad man!