Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats

By Nutramax
Rated 4.4462 out of 5 stars

Breed Size:

Selected: Breed Size:

Breed Size:

Selected: Breed Size:


Selected: Count:


Selected: Count:

$32.99Chewy Price
$31.34Autoship Price
Autoship (Save an extra 5%)

Why Autoship?

  • Save 5% on all future Autoship orders
  • Set your schedule based on your pet's needs
  • No fees, no commitments - skip, change or cancel anytime.

50% Off First Autoship

See Details for instructions to redeem.
In Stock
FREE 1-3 day delivery on first-time orders over $35

About This Item


  • Denamarin contains s-adenosylmethionine (SAMe) to help increase your pet’s glutathione levels and support his liver’s detoxification capabilities.
  • Silybin found in Denamarin has shown better absorption in dogs and cats than the milk thistle extract found in many other products.
  • Supporting your dog and cat’s liver health promotes the liver’s ability to remove toxins, store energy, aid digestion and support the immune system.
  • Nutramax Laboratories Veterinary Science has made supplements to support joint health, digestive health and overall wellness for over 30 years.
  • Veterinarian formulated with high-quality ingredients to ensure supplement safety.

See More

Nutritional Information

Feeding Instructions


Play Video: Learn More About Nutramax From Our Team of Experts
Learn More About Nutramax From Our Team of Experts

Compare Similar Items

Customer Rating
Rated 4.4462 out of 5 stars
Rated 4.6383 out of 5 stars
Rated 3.6162 out of 5 stars
Rated 5 out of 5 stars
Rated 4.375 out of 5 stars
$32.99Chewy Price
$42.99Chewy Price
$44.99Chewy Price
$32.99Chewy Price
$23.99Chewy Price
$31.34Chewy Price
$40.84Chewy Price
$42.74Chewy Price
$31.34Chewy Price
$22.79Chewy Price
Top IngredientsActive Ingredients: S-Adenosylmethionine, Silybin A+B.Active Ingredients: S-Adenosylmethionine, Silybin A+B.Active Ingredients: S-Adenosylmethionine, Silybin A+B.S-Adenosylmethionine 90 mg, Silybin-phosphatidylcholine complex (SPC)* 31 mg, *Providing 9 mg of Silybin A+B....S-Adenosylmethionine.
Breed SizeExtra Small Breeds, Small BreedsSmall Breeds, Medium Breeds, Large BreedsExtra Small Breeds, Small Breeds, Medium Breeds...Small BreedsExtra Small Breeds, Small Breeds
Health FeatureLiver CareLiver CareLiver CareLiver Care, Vitamins & MineralsLiver Care
LifestageAdult, SeniorAdult, SeniorAdult, SeniorAll LifestagesAdult, Senior
Food FormSupplementSupplementSupplementSupplementSupplement

Questions & Answers

23 Customer Questions

Is the medication inside the tablet absorbed even if the outer gel rubbery tablet is still intact after in the stomach for a few hours?
Answer by SpencerSep 14, 2021
I am having the same issue with my small dog. He throws it up intact. I now put a small nick in the gel coating to make sure it dissolves.

When will have this medicine ?
Answer by MillyJun 07, 2022
You can get the one for cats and dogs 12#. It has directions for over 12#

Will this help decrease elevated ALT and ALP levels?
Answer by ChewyJun 12, 2018
Denamarin is a liver support supplement rather than a pharmaceutical product. Due to this, and the fact that every pet and it's needs is unique, Nutramax cannot guarantee efficacy.

Why is this pill blue? Is there a full list of the ingredients for the tablets? My dog has cancer and I'm trying to avoid as much artifical additives as possible.
Answer by ChewyMay 15, 2019
The pill is colored blue using an artificial dye for identification purposes. It you shave off the coloring you will have to use the tablet within 20 minutes.

ReviewsWrite a Review

Rated 4.4462 out of 5 stars
381 Ratings
Would recommend to a friend

376 Customer Reviews

Rated 1 out of 5 stars
By Hannah on Oct 1, 2023
Top 1000 Contibutor

Bummed this didn’t work out for my dogs

I have four senior chihuahuas. Three of them are dealing with elevated liver enzymes. The vet suggested Denamarin. She advised giving it with food. All three of them get sick and vomit after taking it. I also tried giving it on an empty stomach and got the same results. I’m not saying this is a bad product, but it didn’t work for my dogs. Just be aware that it may cause vomiting for your pets too.

Rated 3 out of 5 stars
By Po on Nov 13, 2023

These are huge

Great for a big dog but I have a cat. So it has to be ground up and the coating is sticky. Cat owners: we always get shafted. There's got to be a more cat friendly version

Rated 1 out of 5 stars
By Kate on Oct 4, 2023

new formulation not to Chico's liking

Denamarin used to be a little blue pill that had a smooth surface and rounded edge. the new formulation is a brown pill with a beveled edge and not as smooth surface. My dog does not like it at all. I wish the blue version were still available.

Rated 5 out of 5 stars
By Leslie on Oct 7, 2023

Thank you nutramax

My Pomeranian had elevated liver enzymes at age 13. Vet recommended denamarin and he has been taking it daily for over 2 years with significant decrease in labs. He is now 15 and doing excellent thriving and spunky as ever.

Rated 5 out of 5 stars
By Katherine on Sep 15, 2023

Nutramax To The Rescue!

I have two senior toy poodles who both need to take a liver supplement for different reasons. Denamarin was the recommended medication in both cases. They have both been on the Denamarin for several months and had good check-ups last time around...that, in itself, is reason for celebration!!!

Rated 3 out of 5 stars
By Christine on Aug 7, 2023
Top 1000 Contibutor

Made my cat throw up

I first tried giving the pills from the blister pack to my cat with liver disease. He kept throwing up the pill hours later, in tact! The company explained that the blue pills in the blister pack have a special coating which makes it more difficult to break down, and I should try the beige pills that come in the bottle instead. So, I tried the bottle and he still threw them up. I could not give these to him so I can't comment on their effectiveness. I gave three stars because I do like the company and they were very helpful in trying to solve the vomiting issues. Unfortunately, my cat could not keep them down.

Rated 4 out of 5 stars
By Vicki on Sep 16, 2023

I HOPE it's helping!

Until I get more labwork done on my cat, Aster, it really won't be possible to know how effective this is. Meanwhile, it gives me some peace of mind to know I'm doing SOMEthing for her, based on the recommendations of others.

Rated 5 out of 5 stars
By JeanneD on Jul 24, 2023

Nice to Have Confidence!

It's comforting to know that my dog's Denamarin will arrive on schedule, exactly as requested! I had a hard time finding the Denamarin in my dog's strength, even from my dog's vet! I saw that I could set this up on auto-ship with Chewy and never have to worry about finding it again. It's nice to know that my dog's liver supplement will automatically arrive. I also really like the advance notice that I get from Chewy about a week before it ships. Thanks for such great service!

Rated 5 out of 5 stars
By Charm on Aug 9, 2023

For Cats with Liver Issues

My cat has been taken Denamarin for the past 2 years. It has literally saved her life, bringing her liver readings into a normal range from the high 400's. One pill dropped into the back of her throat each day and she swallows it with no problem. As long as you have a cooperative cat I high recommend this product.

Rated 5 out of 5 stars
By NiksMum on Jul 8, 2023

Effective Product

I bought this for my puppy after discovering that he has liver shunt. Originally, his tests showed high levels for his liver enzymes and after a month of being on this medication, he tested again and his enzyme levels have decreased. We still have a journey to complete but we are hopeful that this product will assist him. He won't take the pill by itself so I give it to him with a little bit of peanut butter.