NUTRAMAX Denamarin Tablets with S-Adenosylmethionine (SAMe) & Silybin Liver Health Supplement for Small Dogs & Cats, 30 count -

Nutramax Denamarin Tablets with S-Adenosylmethionine (SAMe) & Silybin Liver Health Supplement for Small Dogs & Cats

By Nutramax
Rated 4.4848 out of 5 stars
Breed Size

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$32.99Chewy Price
$31.34Autoship Price
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About This Item


  • Denamin contains s-adenosylmethionine (SAMe) to help increase gluthione levels to support your dog and cat’s liver detoxification capabilities.
  • Silybin found in Denamarin has shown better absorption in dogs and cats than the milk thistle extract found in many other products.
  • Supporting your dog and cat’s liver health promotes the liver’s ability to remove toxins, store energy, aid digestion and support the immune system.
  • Nutramax Laboratories Veterinary Science has made supplements to support joint health, digestive health and overall wellness for over 30 years.
  • Veterinarian formulated with high-quality ingredients to ensure supplement safety.

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Nutritional Information

Feeding Instructions


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Questions & Answers

29 Customer Questions

Is the medication inside the tablet absorbed even if the outer gel rubbery tablet is still intact after in the stomach for a few hours?
Answer by SpencerSep 14, 2021
I am having the same issue with my small dog. He throws it up intact. I now put a small nick in the gel coating to make sure it dissolves.

When will have this medicine ?
Answer by MillyJun 07, 2022
You can get the one for cats and dogs 12#. It has directions for over 12#

Is it OK for dog to take CBD while taking Denamarin?

Answer by ChewyJul 09, 2018
Overnight fast meaning not to feed your dog the night prior to treatment.

ReviewsWrite a Review

Rated 4.4848 out of 5 stars
330 Reviews
Would recommend to a friend

330 Customer Reviews

Filter by reviews that mention

Rated 4 out of 5 stars
By AlyOh on Jan 3, 2023

Blue Coating

We were happy to find this available on Chewy after our vet stopped offering it. The replacement from our vet was making our dog sick so we went back to the old option, Denamarin. My only complaint is the blue coating which comes off on everything. It takes a few times to get my dog to swallow her pill and in that time her white fur, my hands, and the pill shooter all become covered in bright blue residue. We didn't have this problem when we were able to get it directly from the vet so I'm not sure what the change has been.

Rated 1 out of 5 stars
By B1234 on Jan 30, 2023

Made my cat throw up

I was giving this my cat for a few days, as the vet recommended a liver supplement for him. He kept throwing up everyday. I discontinued and he has not thrown up at all. Something in this pill makes him very ill. Contacted Chewy and they refunded my money. Great customer service.

Rated 5 out of 5 stars
By fifi on Jan 28, 2023

size of boxes used

The boxes seem overly large for the contents. Since freight isn't charged, it's not an expense to me, but it is a wsste of boxes. perishable liquids are in boxes not labeled "perishable, do not freeze".

Rated 1 out of 5 stars
By B1234 on Jan 14, 2023

Not good, cat kept throwing up

My vet recommend Denamarin. My cat kept throwing up multiple times a day after giving this. I discontinued and there have been no more issues.

Rated 1 out of 5 stars
By Delru on Nov 7, 2022

Hard Pills

Always buy the chewables, which my small dog loves. These have to be shoved down your small pet's throat. No use trying to wrap in a piece of food, as it will be spit out. The chewables for all dogs hasn't been available for MONTHS. No excuse, no reason. Going to find something else other than Denamarin.

Rated 5 out of 5 stars
By VirginiaB on Nov 18, 2022

Cat Actually Swallows with help of Pill Pocket

I'm pleased that I've gotten my cat to swallow these pills with the help of a chicken-flavored pill pocket in with his wet cat food. If he misses it the first time, the bright blue color of the pill makes it easy to spot to do a second attempt.

Rated 1 out of 5 stars
By Delenda on Sep 10, 2022

Terrible taste

So I have had a funny coincidence that I was dog-sitting a tiny dog that took this exact pill. It was really difficult to get him to take it (basically force it down the mouth), and my cat was on SAMelQ and although she wasn’t 100% excited it wasn’t such a battle for her. Fast forward a week and the dog goes home, and my vet switched us to this same pill we were giving the dog. I assumed he was being difficult but then my cat behaved the same way: revolted. Long story short, I never ate them myself but it’s an obvious difference watching multiple animals try it. Something about this design tastes terrible. Going back to SAMelQ.

Rated 2 out of 5 stars
By Earl on Sep 25, 2022

Doesn't Dissolve

My cat's ALT levels came back really high and this supplement came highly recommended. After two days of supplementation my cat vomited up each pill from day one and two. Both pills had just sat in his digestive tract undissolved. Upon Googling the pill, I read that the pills can cause digestive upset and vomiting. I am concerned that they just sat in his system for two days aggravating his digestive system.

Rated 5 out of 5 stars
By Catmom on Oct 21, 2022

This stuff is a miracle

My cat had elevated liver enzymes, so her vet recommended this. She has been on this for almost 3 weeks and at her last visit, her enzymes had stabilized. Will continue to purchase and thank you for providing this at an affordable price.

Rated 5 out of 5 stars
By Jules on Jan 10, 2023

Denamarin Tablet

These tablets are so much easier to give than the chewable. They aren't bitter and work just as well.