Nutramax Laboratories Denosyl Liver & Brain Health Supplement Stabilized Tablets for Large Dogs, 30 count

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  • All Lifestages
  • Medium Breeds
  • Large Breeds
  • Giant Breeds

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$54.99 List Price
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About This Item

Details

  • Denosyl contains S-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione—one of the liver’s main detoxifying agents.
  • Support your larger pup’s liver health and boost its ability to remove toxins, store energy, aid digestion, and support the immune system.
  • While best known for supporting the liver in pets, the SAMe in Denosyl may also help support cognitive function.
  • Rest assured, Nutramax produces Denosyl to ensure your dog receives a safe, high-quality product.
  • Nutramax has been a leader in pet health for more than 30 years, providing supplements to support joint health, digestive health, skin and coat health, calming, and more.

Ingredient Information

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Questions & Answers

6 Customer Questions

what is this product used for?

Answer by Chewy • Apr 30, 2024
The Nutramax Denosyl tablets help support the liver health of dogs and may support brain health. Denosyl has been found to enter your dog’s bloodstream to help support the liver and may also support your dog’s cognitive function.

Can this medicine be given crushed up or must be swallowed?

Answer by Chewy • Feb 24, 2018
For optimal absorption, it is recommended to give tablet(s) whole, on an empty stomach at least an hour prior to a meal.

Will this lower my dog's Alk Phosphate in liver chem profile? That's the one that is still very high out of his LFT's

Answer by Chewy • Jul 09, 2019
The SAMe (S-Adenosylmethionine) in Denosyl helps to produce a certain antioxidant. This antioxidant helps to facilitate normal cellular function of the liver.

After I give my dog the pill can she drink water??

Answer by Chewy • Jan 27, 2019
It is actually recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach. However, only meal intake is warned against surrounding the time of administration, so your pet should be able to drink water normally as well.
Reviews
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4.7
Rated 4.7 out of 5 stars
140 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

87% Positive

Effectiveness

80% Positive

Ingredients

84% Positive

Long-Term Benefits

84% Positive

73 Customer Reviews

Rated 5 out of 5 stars
By S on Dec 18, 2025

Easier to have our pup swallow

While we still have to put it in cheese, it’s way better than the other product we initially bought (and Chewy refunded us without my asking simply because they

While we still have to put it in cheese, it’s way better than the other product we initially bought (and Chewy refunded us without my asking simply because they saw my review about my dog being unwilling to eat it) love this company!

Rated 4 out of 5 stars
By Elizabeth on Sep 21, 2025

Nice sock to prevent licking

We are using one of these socks to prevent licking. These are quite snug on the ankle. My foxhound has what I consider normal feet and legs for a 50lb dog. The

We are using one of these socks to prevent licking. These are quite snug on the ankle. My foxhound has what I consider normal feet and legs for a 50lb dog. The measured foot fit him in the medium. They fit the foot, but were too tight above, so I stretched them out overnight before using. They stay up pretty well and the grip on them for hardwood is great. He isn't a chewer and leaves the sock alone, so I can't speak to longevity.

Rated 5 out of 5 stars
By Rossana on Dec 11, 2025

Vet requested

Andi's vet requested we purchase. Has been taking for 1 month. Time will tell on the next bloodwork order.

Andi's vet requested we purchase. Has been taking for 1 month. Time will tell on the next bloodwork order.

Rated 5 out of 5 stars
By Kelly on Sep 5, 2025

A lot cheaper than the vet

Winston is a silver lab that has liver issues he is 11 years old and Denosyl has helped with his liver issues so much. I hope to have Winston with me for a lot

Winston is a silver lab that has liver issues he is 11 years old and Denosyl has helped with his liver issues so much. I hope to have Winston with me for a lot more years and I'm crediting this medicine in making him feel better.

Rated 5 out of 5 stars
By Tanya on Jul 4, 2025

Review

This alternative brand was what are veterinarian assistant recommended us try because the brand they gave us at the office was a different brand but she said it

This alternative brand was what are veterinarian assistant recommended us try because the brand they gave us at the office was a different brand but she said it was the same type of medication. The veterinarian office charges way too much for anything I'm grateful that chewy is available to give us a better price

Rated 5 out of 5 stars
By Cristine on Sep 4, 2025

They work!

My dogs liver panel (ALT) was bad, Over 900. After giving her these pills for 3 weeks, it has dropped below 400.

My dogs liver panel (ALT) was bad, Over 900. After giving her these pills for 3 weeks, it has dropped below 400.

Rated 5 out of 5 stars
By Kenny on Oct 10, 2025

NUTRAMAX

Very good supplement. keep Give my dog, healthy and happy.

Very good supplement. keep Give my dog, healthy and happy.

Rated 5 out of 5 stars
By Pamela on Dec 8, 2025

Ease

Easy for me to give him his dose

Easy for me to give him his dose

Rated 5 out of 5 stars
By Frank on Sep 27, 2025

Denosyl medication

Arrived on time, as expected, Thank You!

Arrived on time, as expected, Thank You!

Rated 5 out of 5 stars
By Diane on Sep 2, 2025

Price vs. VET

Veterinarian charges $25 more for a 30 day supply

Veterinarian charges $25 more for a 30 day supply