Percorten-V (desoxycorticosterone pivalate) Injectable for Dogs, 25 mg/mL, 4-mL vial

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About This Item

Details

Percorten-V is an injectable prescription medication formulated to help dogs manage canine Addisons disease. This complex disease affects the adrenal glands and can happen to dogs of any age. Percorten-V has a history of proven success and by monitoring your pet and administering regular injections, it can help your dog get back on track and back to his daily duties.

We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.

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4.8
Rated 4.8 out of 5 stars
288 Ratings
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Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

89% Positive

Effectiveness

89% Positive

Ingredients

92% Positive

Long-Term Benefits

88% Positive

105 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Laura on Dec 8, 2025

Our dog needs this to live

One of our dogs was diagnosed with Addison's Disease and she will be turning 4 years old this month. She needs this medicine injected every 25 days for the rest

One of our dogs was diagnosed with Addison's Disease and she will be turning 4 years old this month. She needs this medicine injected every 25 days for the rest of her life and it's expensive but so far she's doing good. She was in critical condition when we took her first to an Urgent Care place and then to an Emergency Hospital and both places said it was Addison's Disease and at the time they didn't know if she would survive the night but with everything they did for our pup she is now back to normal as long as she gets her injections and she also gets Prednisone daily (just 1/4 of a pill). I just wish this medication was cheaper since we won't be able to use the whole vial (once it's used the first time it has to used in 4 months). Our dog Piper is only 13 lbs so her dosage is small every 25 days so we won't go through a vial in 4 months time. So we will need to purchase this medication every 4 months. We have a vet tech give the injections (we take the vial with) because both me and my husband are senior citizens and we don't want to be the ones to give the injections.

Rated 5 out of 5 stars
By Lorrie on Dec 19, 2025

Our dog has Addison’s disease.

Our dog relies on a monthly shot of this Percotten V. We go back to the vet every couple of months to make sure our dog is getting the right dosage. The vet has

Our dog relies on a monthly shot of this Percotten V. We go back to the vet every couple of months to make sure our dog is getting the right dosage. The vet has slowly lowered the dose according to the blood work results. This medication has saved my dog’s life.

Rated 4 out of 5 stars
By Rachael on Dec 27, 2025

Life saving but expensive

This medication as saved my dog's life. He was diagnosed with Addison's this past summer after almost dying. This med has literally saved his life. My only issue

This medication as saved my dog's life. He was diagnosed with Addison's this past summer after almost dying. This med has literally saved his life. My only issue is that it is horribly expensive, $240 a month, and we have to have it or our dog will die.

Rated 2 out of 5 stars
By Jared on Jan 24, 2026

Expensive, life saving drug, and you increased the price 25%

Life saving but Chewy's should stop charging state sales tax on drugs. Also, help us fight to get drug costs down. Ridiculous. $250 for 4 mL?

Life saving but Chewy's should stop charging state sales tax on drugs. Also, help us fight to get drug costs down. Ridiculous. $250 for 4 mL?

Rated 5 out of 5 stars
By Lisa on Dec 28, 2025

Pharmacy is amazing!

Cody needs special meds for his medicine and Chewy’s pharmacy has been so helpful answering questions and it is truly the best price I have found for Cody.

Cody needs special meds for his medicine and Chewy’s pharmacy has been so helpful answering questions and it is truly the best price I have found for Cody.

Rated 5 out of 5 stars
By Shawn on Oct 20, 2025

It works

Between this every 25 days and her prednisone tablets she's the happiest healthiest dog I've ever seen her in my life she's also getting hill science diet and dasaquin

Between this every 25 days and her prednisone tablets she's the happiest healthiest dog I've ever seen her in my life she's also getting hill science diet and dasaquin chews and nature's pet fish oil a couple of squirts with each meal this dog is the happiest most healthy vibrant I've ever seen her in her entire life she's almost 7 and she's like a puppy again and I can barely hold her back ... Phew!

Rated 5 out of 5 stars
By Wesley on Nov 19, 2025

Does not burn

I used to use Zycortol, but it got more expensive. I tried Percorten out and it was so much better. It does NOT burn, so I can give the injections without traumatizing

I used to use Zycortol, but it got more expensive. I tried Percorten out and it was so much better. It does NOT burn, so I can give the injections without traumatizing my dog. It really is great!

Rated 4 out of 5 stars
By Kaylee on Sep 2, 2025

Saved my babies life!

My boy went through an Addisonian crisis in April of 2024 where we almost lost him. Thankfully, our emergency vet was able to diagnose him in time with Addison’s

My boy went through an Addisonian crisis in April of 2024 where we almost lost him. Thankfully, our emergency vet was able to diagnose him in time with Addison’s disease and give him an injection of Percorten which worked within MINUTES. Ever since his diagnosis, we have been doing at home injections every 25 days. He does fantastic for them and even seems to be much more lively the next day after his injection. My only gripe is how expensive this life-saving injection costs. If the price could be reduced even by some that would be exponentially helpful to any consumer who REQUIRES to give this medication monthly to their pets.

Rated 5 out of 5 stars
By Patricia on Sep 30, 2025

Addison disease

Our furr baby althea has Addison disease, we were getting the shot through our vet which wasn't cheap, then we started giving it at home and received it thru chewy

Our furr baby althea has Addison disease, we were getting the shot through our vet which wasn't cheap, then we started giving it at home and received it thru chewy half the price. What a life saver. We love chewy for so many reasons....

Rated 5 out of 5 stars
By Dorothy on Sep 14, 2025

Prevents an Addison’s Disease attack

My dog has not had an Addisonian attack in several years, thanks to this product. Just wish it came in a pill form or chewable so I wouldn’t have to take him to

My dog has not had an Addisonian attack in several years, thanks to this product. Just wish it came in a pill form or chewable so I wouldn’t have to take him to the vet each month for the injection. The trip going to the vet is very stressful for him.