Regu-Mate (Altrenogest) Solution for Horses, slide 1 of 1

Regu-Mate (Altrenogest) Solution for Horses, 1000-mL

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Regu-Mate Solution for Horses is specially formulated to help suppress extrus, the period of the reproductive cycle when the mare ovulates. This not only helps provide you with control over your mare’s reproductive cycle, but it can also help reduce undesirable moods and changes in her behavior. Mares who had a regular estrous cycle prior to treatment typically return to estrus in four to five days after treatment and then go back to their normal cycle. Typically, Regu-Mate helps suppress estrus in 95% of mares after just three days of treatment.

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Regu-Mate (altrenogest) Solution 0.22% is indicated to suppress estrus (period of the reproductive cycle when the mare ovulates and, if bred, is likely to conceive) in mares.

Possible Side Effects

When used as directed on the label, Regu-Mate is usually tolerated well by horses. Consult with your veterinarian for any potential side effect concerns.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your pet is taking before starting this medication.


Regu-Mate (altrenogest) is contraindicated for use in mares having a previous or current history of uterine inflammation. Pregnant women or women who suspect they are pregnant should not handle Regu-Mate. Women of childbearing age should exercise extreme caution when handling this product. Accidental absorption, such as via direct contract with the skin, could lead to a disruption of the menstrual cycle or prolongation of pregnancy. Vinyl, neoprene, or nitrile gloves must be worn by all persons who handle this product or who come in contact with equipment or surfaces contaminated by this product. For complete safety information please read label.

  1. Prescribing Information

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  • Item Number
  • Generic Name
  • Common Brand Name(s)
  • For Use With
  • Administration Form
  • Product Form
  • Health Condition
    Estrus Postponement
  • Drug Type

Synthetic Progestin, Altrenogest 22%.

Recommended Dosage

Administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days.

Storage Instructions

Store at or below 25 degrees C (77 degrees F).


What are the benefits of Regu-Mate?

  • The only FDA-approved altrenogest with more than 50 million doses sold

  • Delivers safe, predictable control over a mare's reproductive cycle and reduces undesirable mood and behavioral changes

  • Strategic use helps accommodate mare's performance schedule

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