SELEGILINE HCl (Generic) Capsules for Dogs, 5-mg, 60 capsules -

Selegiline HCl (Generic) Capsules for Dogs, 5-mg, 60 capsules

By Selegiline
Rated 4.2895 out of 5 stars
Prescription Item

$64.99Chewy Price
$61.74Autoship Price
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About This Item


Selegiline is an oral prescription medication used to treat cognitive dysfunction and senility in older dogs. It can also be used to treat Cushing's disease when it is caused by a pituitary tumor. It’s a generic alternative to Anipryl, and it’s the only FDA-approved drug for canine senility. It comes in a capsule form, so you can easily hide it in a pill pocket and give it as a tasty treat or disguise it in your pal’s favorite wet food. Customers may receive this drug under the names l-deprenyl, Anipryl, Eldepryl.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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ReviewsWrite a Review

Rated 4.2895 out of 5 stars
38 Reviews
Would recommend to a friend

38 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Budi on Aug 28, 2022

Used for CCDS

I purchased Selegiline from my vet for my 17 year old poodle. It appeared to combat many of the symptoms he was experiencing, in fact I felt he was almost his self again. When the med Of 30 pills ran out, I contacted Chewy for a refill, at half the cost of the vets. It's a generic, but works just as well. It is in capsule form. I put it in pill pockets and he takes it fine. He is now responding and acts like a much younger dog, without side affects.

Rated 5 out of 5 stars
By BlackLab60lbs on Sep 5, 2022

Life Saver!

Our 15 year old terrier has Dementia. For over a year, her pacing, panting and confusion was increasingly getting worse. She would even pee in the house, not because she was losing control, but because she didn't know where she was. She was also losing her sight and hearing. This all sounds horrible, but she was also very playful with our 2 year old lab! Not only that, but since we kept her routine consistent and kept her surroundings (furniture) the same, she could navigate on her own. The pacing and panting for HOURS drove us crazy though! Our vet recommended this medication and within just three days, we noticed less pacing and panting. It has been 5 weeks now and the pacing and panting is VERY minimal. I don't even notice it anymore. Thank goodness! We do have to keep her outside due to the urinating in the house, but we are setting her up for success for that, so don't worry. I am reordering the medication today because she is less stressed, there were no side effects and our family is happier. I highly recommend this medication to comfort your pet, and family.

Rated 1 out of 5 stars
By BarbH on Sep 4, 2022

Gave my dog a seizure

I wouldn't recommend this drug. My dog had a seizure after taking it

Rated 5 out of 5 stars
By Sunshine on May 26, 2022

Save Money!

I am getting twice the amount as I received at CVS for the same price. My vet is planning to spread the word.

Rated 5 out of 5 stars
By Tuuka on Mar 12, 2022

Selegiline to the rescue

Tuuka is our 9 yr old 95lb OEB and was presenting the classic symptoms mentioned in other reviews like starring at walls etc. Within 24 hours he was showing improvement and more than a week later he is significantly better. I am treating him with 10mg every morning. Good luck

Rated 3 out of 5 stars
By expensive on Jan 25, 2022

Worked at first but...

I have a 100lb 12-year-old Chocolate Lab (Buster) who was recently diagnosed with Canine Cognitive Disorder (CCD). He would pant constantly beginning at nighttime and pace the floors. He and I both were very disturbed by this behavior and not getting regular sleep. I first tried this Rx at the vets recommended dose of 30mg per day, but he only got or acted way worse. So, I quickly discontinued giving it to him and went back to trazadone and xanax. I found this 5mg dose and asked if we could give this lower dose a try. I observed almost immediate results after giving him the 5mg dose. Within a few days, he was only taking this 1 medication and occasionally would need a low dose of xanax (.50mg). He continued to show signs of improvement for several weeks, but now, the panting and restlessness has begun again at nighttime. I began giving him 10mg (2 pills) per day along with up to 1.5mg of xanax, but so far, he has continued panting and being restless at night. I cut him back to 1 pill (5mg) this morning and am going to see if this helps. If not, I will begin him on 15mg (3 pills) per day to see if that helps. At first we were greatly relieved and wowed by the positive effects and am still hopeful. Seems to just take time to find his right dosage. If you have a pup that has CCD, I would recommend giving this medication a shot. I personally don't like to take medications and also don't want to give them to my buddy if not absolutely necessary. Hoping to find a dosage that helps him and us have peaceful nights once again, soon.

Rated 5 out of 5 stars
By Mogs on Mar 12, 2022

Doggy dementia

My dog is a senior boxer dog. She is approximately 13, maybe 14 years old. At night, she has been pacing, whining, and not sleeping. The gabapentin alone was not working. This medicine took about 1.5 weeks to kick in but definitely helps regulate her sleep wake cycle and helps her sleep.

Rated 3 out of 5 stars
By Barbra on Dec 29, 2021

Should start earlier

This medication should be started with a old dog when their cognitive skills first begin to decline. We started our dog on it after he had a stroke. He was a 15 year old peke. He unfortunately died today as he never recovered from his stroke. Feel like this is a good medication if started at the onset of neurological symptoms with older dogs.

Rated 5 out of 5 stars
By Kelly on Dec 10, 2021

Miracle for Molly!

In early 2020 our then 12 year old yellow lab started showing some signs of cognitive decline. By mid summer, she was panting nearly all day, it was taking her 1-2 hours to settle in the evening, and she still woke frequently to pace and pant overnight. She became unable to cross wood floor transitions, and had frequent episodes of seeming confused/frozen in place inside the home she’s lived in her entire life. It got to the point where it was severely impacting her quality of life, and our emotional sanity as well. It took some convincing to get our vet to prescribe it, but within two weeks of the med we saw significant change. Now a year later, Molly’s mental status is sharper than it had been for years. She’s happy, playful, and no longer pants/paces/wakes through the night. It’s expensive and we go through it quickly, but the improvement has been so life changing that it’s well worth it. Plus Chewy has the best prices of anywhere. Molly is dealing with several other “old lady” health issues at this point being nearly 14, but we are so thankful to have found this incredible drug for her senior years!

Rated 5 out of 5 stars
By Izzy on Oct 25, 2021

It finally worked

My 15 year old Yorker had been getting up at night barking pacing / when I would let him outside he would stare at the fence with no need to relieve himself. This would last most of the night. My Vet gave me Selegiline. It took 8 weeks before his behavior changed. He now sleeps through the night. For me it’s a miracle, be patient it does work.