Senergy Topical Solution for Dogs, 20.1-40 lbs, (Red Box), 3 Doses (3-mos. supply)

Have a Chewy account?
Sign in to quickly add pet health details.
$33.72 First Time Autoship Price
this order
Save 35% (up to $20) today when you set up Autoship. 

$49.28 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Never miss a dose with easy refills
  • Skip, change, or cancel anytime
$51.87 Chewy Price
($17.29 /ea)
Save $3.52 (-6%)
$55.39 List Price
Promo, Save 20% on first Rx order with code RX20
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

In Stock
FREE delivery
Usually arrives in 3-5 days
Prescription approval made easy
We’ll reach out to your vet clinic.

No interest if paid in full in 6 months on PayPal purchases of $149+. .

Medications ship separately. Delivery times may vary.

About This Item

Details

Senergy is a convenient topical parasiticide for your doggie dude that is designed to help prevent heartworm disease while killing adult fleas and deterring flea eggs from hatching for one month. It may also be used to aid in the treatment and control of sarcoptic mange and ear mite infestations as well as the control of tick infestations.We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.

Ingredients

Instructions

FAQ

Learn More About Senergy From Our Team of Experts
4.6
Rated 4.6 out of 5 stars
37 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

88% Positive

Effectiveness

80% Positive

Ingredients

95% Positive

Long-Term Results

88% Positive

13 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
By Danielle on Nov 24, 2025

Not effective for all ticks

We found out after the fact that this medication only covers ONE type of tick - dogs are still susceptible to all other tick species. During a weekend in the Catskills,

We found out after the fact that this medication only covers ONE type of tick - dogs are still susceptible to all other tick species. During a weekend in the Catskills, we found 20+ ticks on our dog despite being on this preventative for months. We took her to the vet twice after our trip for additional tick checks, and we just found out that she is positive for Lyme disease.


Rated 5 out of 5 stars
By WILLIAM on Oct 18, 2025

Easy to apply

Ginny won’t take pills easily and this seems to be working.

Ginny won’t take pills easily and this seems to be working.


Rated 5 out of 5 stars
By Lisa on Sep 15, 2025

A good flea treatment with the lowest side effects

It works and does not have bad side effects

It works and does not have bad side effects


Rated 5 out of 5 stars
By Jolanta on Dec 26, 2025

Easy to reorder

Easy to reorder

Easy to reorder


Rated 5 out of 5 stars
By Lucy on Aug 6, 2025

Flea medication

It works well

It works well


Rated 3 out of 5 stars
By Anne on Sep 4, 2024

Lackluster flea results

I still have itching and stretching dogs with fleas.

I still have itching and stretching dogs with fleas.


Rated 5 out of 5 stars
By carol on Jul 31, 2024

Great easy to use

My dog hates pills so this is a great product

My dog hates pills so this is a great product


Rated 5 out of 5 stars
By Stephen on Oct 3, 2024

Effective

Quick delivery easy to use

Quick delivery easy to use


Rated 5 out of 5 stars
By Mary on May 16, 2024

ticks and fleas

This product I have been using and I think is good.

This product I have been using and I think is good.


Rated 5 out of 5 stars
By Judy on Dec 2, 2022

very happy with effectiveness and ease of use

Today is the third month i've given this to my two dogs, one is 3 1/2 Cavalier King Charles, the other is an 8 year old cocker spaniel mix, 21 lbs and 27 lbs. For

Today is the third month i've given this to my two dogs, one is 3 1/2 Cavalier King Charles, the other is an 8 year old cocker spaniel mix, 21 lbs and 27 lbs. For 13 years of my previous dog's life i gave Revolution and it worked well. Also, treating the yard with nematodes may have helped. I also use Capstar in combination with this kind of monthly flea preventative. Revolution and Senergy use the same drug, selemectin. Senergy is a generic brand of Revolution. I didn't know until about 6 months ago that there was a generic alternative to Revolution. In fact there are at least two. I learned this because all of a sudden i couldn't get Revolution. It wasn't available for many months. There was some problem with the production or distribution. One of my vets wio prescribed it for my dog told me there was a generic version which was available at Chewy. It wasn't this one, it was another one, i think it's called Selarid but i might have the spelling wrong. It turned out that Selurid was also not available but i learned that Senergy was another one, and there was one more, and those were in stock. i needed the medication, i had to try one of them. i ordered Senergy. It's similar to Revolution in how you apply it to the back of their neck. Unlike Revolution, Senergy doesn't have an odor i can smell, kind of a pesticide odor which neither i nor my dogs liked. Senergy doesn't have it. Opening the tip of the dose container is easier than Revolution. It's not a big difference but Revolution was a little more complicated. As i said i usually will use it together with Capstar, when i first apply it, if the dogs are scratching. Capstar is a very short acting flea killer. It lasts 24 hours and then it stops. It starts killing fleas right away, within a half hour and will give a dog quick relief that lasts 24 hours if it works as it's supposed to. It always has for me. So, i think it gives the selemectic a good start by killing off a lot of fleas at the beginning of the selemectin dose, and i may give it for up to if the scratching comes back but i can always see it die down in the first days of selemectin, and my last three doses have been the Senergy generic brand. Senergy and the other generics are A LOT cheaper than Revolution. Senergy only comes in 3 month maximum doses. i hope that changes but i have it for two dogs so i know what 6 months would cost if they had it for one dog. Revolution is close to $140 for 6 months. Senergy is about $100 for six doses. Each time i've given it to my dogs, by the second or third day, they are no longer scratching repeatedly. One of them may scratch now and then but no longer frequently. I do use the Capstar at the beginning, but i would have no problme using it by itself without the Capstar. Capstar is pretty expensive, it's not meant to be used ongoing as a monthly preventative. It's meant for things like, if you take your dog to a dog park where they might get exposed to fleas, you give Capstar when you leaved the dog park and by the time you get home all the fleas will be dead so they won't get in your house. Anyway, i can't say how happy i am to have a much more affordable effective selemectin medication and once again, i'm seeing the end of itching. i did give a Capstar today so that is to be expected. i don't see selemectin as fast acting. in my experience it should be in effect by into the third day and notice