Synovi G4 Soft Chews Joint Supplement for Dogs, slide 1 of 1

Synovi G4 Soft Chews Joint Supplement for Dogs

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Synovi G4 Joint Health Soft Chews for Dogs are recommended to support joint function and flexibility and help strengthen joint cartilage in dogs as they age. Formulated with a synergistic blend of antioxidants in a highly palatable soft chew, Synovi G4 helps your dog maintain a healthy lifestyle. Powerful ingredients such as glucosamine, creatine, MSM, turmeric and boswellia serrata promote joint health, so getting older doesn't have to mean feeling older.

Key Benefits
  • First step in a total joint health management protocol
  • Combines joint health agents boswellia serrata extract, turmeric, glucosamine, MSM, creatine, perna canaliculus, vitamins C and E and other antioxidants
  • Supports overall joint function and flexibility, and helps strengthen joint cartilage in dogs as they age
  • Contains a synergistic blend of antioxidants to help fight free radicals and maintain a healthy lifestyle
  • Tasty, highly palatable soft chew form makes administering to your dog easy and enjoyable

For animal use only. If lameness worsens, discontinue use and contact your veterinarian. Administer during or after the animal has eaten to reduce incidence of gastrointestinal upset. ALWAYS read the entire product label prior to use.

See all items by Synovi

  • Item Number
  • Lifestage
    Adult, Senior, Puppy
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds, All Breeds, Giant Breeds, Extra Small & Toy Breeds
  • Food Form
  • Product Form
    Soft Chew
Nutritional Info

Active Ingredients: Glucosamine HCl (Shellfish), Methylsulfonylmethane (MSM), Creatine Monohydrate, Boswellia Serrata Extract (Containing 65% Boswellic Acids), Perna Canaliculus, Proprietary Blend of Dicalcium Phosphate, Citrus Bioflavonoids, Ascorbic Acid (Vitamin C), Manganese Sulfate, Grape Seed, Extract, Zinc Sulfate and Alpha Lipoic Acid, Curcuma Longa (Turmeric), Selenium (as L-Selenomethionine), D-Alpha Tocopheryl Acetate (Vitamin E). Inactive Ingredients: Cane Molasses, Corn Starch, Dried Poultry Liver, Glycerin, Lecithin, Mixed Tocopherols, Potassium Sorbate, Soybean Oil, Sugar, and Wheat Flour.

Feeding Instructions

Boswellia and Turmeric enriched joint health complex combining Glucosamine, MSM, Creatine and a novel blend of Antioxidants in a highly palatable soft chew. For use in dogs only. Recommended to support joint function, flexibility, and joint cartilage. Can be given during or after meal time. Maintenance recommendations: * 5 - 15 lb - 1/2 chew every other day * 16 - 30 lb - 1/2 chew daily * 31 - 60 lb - 1 chew daily * 61 - 100 lb - 2 chew daily * over 100 lb - 2 1/2 chews daily


How is Synovi G4 different from other joint supplements?

Synovi G4 builds upon the success of the Synovi G3 matrix, a blend of various joint health ingredients, including glucosamine, manganese and green-lipped mussel, which has sold over 250 million doses. Synovi G4 is enriched with the naturally-derived ingredients turmeric, a potent antioxidant, and Boswellia serrata. Laboratory studies have shown that Turmeric and Boswellia serrata help support a healthy inflammatory response.

What is Boswellia serrata? Boswellia serrata, also known as Indian frankincense, is a large branching tree native to India, Northern Africa, and the Middle East. The tree's resin contains boswellic acids, which have shown in laboratory studies to support a healthy inflammatory response and promote joint health. Boswellia serrata may also help with occasional discomfort and joint stiffness due to daily activity.

What is Turmeric?

A plant of the ginger family native to Asia and India most commonly associated as a spice for cooking. The active component, curcumin, is a yellow phytochemical extracted from the plant's roots. It contains free radical scavenging abilities and has shown to assist in the synthesis of important cellular enzymes.

Why does Synovi G4 not contain chondroitin?

Synovi G4 is based on the joint health ingredient matrix found in Synovi G3 which contains Perna canaliculus, also known as Green-lipped mussel, found off the coastal waters of New Zealand. Perna is a source of chondroitin as well as Omega-3 fatty acids.

Why did you choose the combination of Boswellia and Turmeric?

These two ingredients were added because they are not commonly found in traditional joint supplements and are known for a variety of health benefits. A growing body of evidence indicates that both Boswellia and Turmeric may be beneficial in the support of healthy joints, including cartilage and connective tissue, as well as a healthy inflammatory response.

How can I use Synovi G4? Synovi G4 can be used as a standalone product or in coordination with Free Form' and/or Alenza Soft Chews for additional supplemental support or as directed by your veterinarian. Joint supplements are typically given to dogs that are starting to age, may be slowing down, or have trouble climbing stairs. For active dogs, a joint supplement can also help maintain joint health and mobility.

Will Synovi G4 interfere with other medications my dog may be taking?

There are no known contraindications for Synovi G4 but always tell your veterinarian about all the medications and supplements that you give your dog.

What can I expect after giving Synovi G4 to my dog? It varies depending on a wide scope of factors, such as lifestyle, genetic predispositions, body condition, and type of discomfort. It is possible pet owners may notice some benefit within 2-4 weeks.

Can I use Synovi G4 for my cat?

No. Synovi G4 is labeled for use in dogs only.

How should Synovi G4 be stored? Store at room temperature in a location your dog can't access.

Synovi G4 is provided in a tub and should be kept sealed and stored at room temperature when not in use. It does not require refrigeration or any other special storage.

When should Synovi G4 be given?

Synovi G4 can be given during or after meal time.

How many Synovi G4 Soft Chews should I give to my dog each day?

WeightMaintenance Recommendations
5 to 15 lbs 1/2 chew every other day
16-30 lbs 1/2 chew daily
31-60 lbs 1 chew daily
61-100 lbs 2 chews daily
Over 100 lbs 2 1/2 chews daily

Can I give my dog more than the recommended amount?

No. Please follow the maintenance recommendations as listed on the product label.

How long will a 60-count, 120-count and 240-count tub of Synovi G4 last?

Assuming only one dog is receiving Synovi G4, each tub count will last according to the table below:

5 to 15 lbs16 to 30 lbs31 to 60 lbs61 to 100 lbsOver 100 lbs
60 count8 months4months2 months1 month24 days
120 count16 months8 months4 months2 months48 days
240 countup to 24 months16 months8 months4 months3 months

What is the protein source for Synovi G4 (flavor)?

Poultry liver.

Synovi G4 is not intended for patients with known hypersensitivity to any of the ingredients in the product.

What is the National Animal Supplement Council (NASC)?

The National Animal Supplement Council is a nonprofit industry group dedicated to protecting and enhancing the health of companion animals throughout the U.S. The overriding goal of the NASC is to promote the health and well-being of cats and dogs that are given animal health supplements by their owners, and to protect and enhance the integrity of the animal health product industry.

What is the National Animal Supplement Council (NASC) Quality Seal found on Synovi G4 and all Bayer supplements?

The NASC Quality Seal program was initiated as part of the NASC's ongoing effort to improve and standardize the animal supplement industry.

The Quality Seal is a way for consumers to know the product they are buying comes from a manufacturer that voluntarily complies with standards set forth by NASC.

NASC member companies must comply with rigorous requirements before they are granted permission to display the seal:

When you see the Quality Seal on a product, you can trust it comes from a reputable company that has successfully passed an independent quality audit.

Look for the NASC Quality Seal on Synovi G4 and all Bayer supplements.

Why should I include vitamins & supplements in my pet's diet?

Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet's exact health needs. Like in humans, vitamins and supplements can help support your pet's long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.

How often should I give this supplement to my pet?

It is recommended to give the suggested dosage based off your pet's weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.

Is this supplement safe to use with the medication my pet is currently taking?

If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.

My pet is allergic to certain ingredients, will this product be safe to use?

For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.

Does this product come in other product forms?

For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

About Synovi G4

Experience the Benefits of Synovi G4

Experience the Benefits of Synovi G4

Normal wear and tear can take a toll on your dog’s joints over time. Don’t let pain and stiffness slow him down! Synovi G4 Soft chews help your best bud maintain good joint health with a mix of agents that support stronger joints and less inflammation.

Keeps ‘Em Moving

Key ingredients in Synovi G4 support ongoing joint health and ease of movement as pups age. Glucosamine, boswellia, turmeric and green-lipped muscle contain powerful compounds that assist proper joint function and help control inflammation. Help your buddy feel his best so he can stay active and healthy.

Targeted Support for Joints

Targeted Support for Joints

Synovi G4 targets the root causes of pain and stiffness. It works to support proper cartilage formation, so hips and joints stay flexible and retain function over time. Antioxidants and anti-inflammatories promote a healthy inflammatory response, so pain and stiffness won’t hound your best friend. Ideal for all ages, sizes and breeds, Synovi G4 aims to keep your best buddy full of vigor and free from pain.

What's in Synovi G4


Glucosamine helps keep cartilage healthy, while Boswellia helps with knee-joint function and can reduce inflammation.


These compounds work to reduce painful inflammation and provide free-radical scavenging antioxidants.


Provides a natural source of chondroitin, which helps shore up cartilage and enhance its resilience.


Works to enhance muscle tone around the joints and provides contraction support.

Bayer Supplement Brands




Free Form™

Free Form™


What Is It?

Joint Health

Healthy Aging

General Wellness

General Wellness

GI Support


A daily soft chew that provides ongoing mobility and joint support.

A daily soft chew for dogs that promotes joint health and helps maintain comfort throughout the body as dogs age.

Omega-3 fatty acids that support sensitive skin, eye, joint, brain, heart, kidney and immune health.

Omega-3 fatty acids that support sensitive skin, eye, joint, brain, heart, kidney and immune health.

A daily probiotic soft chew for dogs. Offers ongoing digestive health support.

Key Ingredients

Glucosamine, green-lipped mussel, Boswellia, turmeric

Baicalin, catechin, Boswellia

Fish oil (anchovies)

Fish oil (anchovies)

Probiotic (live microbes), prebiotic (inulin)

Count Size

Soft chew

Soft chew

Gel Cap


Soft chew








60, 120, 240

60, 90

60, 250

4 oz. liquid


About Bayer

Bayer has been working to make the lives of pets better for over a century, with innovative, science-based solutions that help them stay healthy and strong. They offer a full line of supplements designed specifically for our furry friends, to help them live their longest and happiest lives right by our side.

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