Tylosin Tartrate (Generic) Soluble Powder, 100-gm

This powder is extremely thin and bitter, it gets into your nose when you open the lid. The price is interesting, but I prefer the original brand for a bit more money. Easier to handle and mix with food

We’ve had the privilege of parenting 3 different Basenjis over the years. Our current boy has a lot of GI “issues” and despite a draconian diet of hydrolyzed protein kibble w no other foods or snacks, he still gets diarrhea from time to time for no apparent reason. He also became refractory to Metronidazole which has been our go-to. Our vet suggested Tylosin, and it has been remarkably effective. There are a number of dosage regimens out there, so I won’t get into that aspect. We settled on a once-a-day regimen whenever he “falls off the wagon,” and continue for 3-4 days. We found that 1 dose is often sufficient to fix the problem, but if we don’t follow up for 3-4 days, diarrhea comes right back. On the issue of mixing and administering, we’ve tried many techniques. First, we found that adding water TO the powder as noted on the pouch, often leads to clumping. We found that putting about 1 TSP room temp H2O in a medicine cup and then sprinkling the powder on top works very well. After sprinkling, do NOT stir. Just let the Tylosin dissolve by itself over 5-10’. Also, Tylosin has a distinct “chemical-ly” aroma. We mask that by adding 1/2 TSP of Maple Syrup after the Tylosin has dissolved. We then draw up the mixture in a syringe w a rubber catheter tip and slide the catheter tip along his gums on the side, over his tongue w head back and slowly drizzle so he can swallow and not aspirate. Have used this technique for some 8 years and it’s very satisfactory.