Adequan Equine i.m. (polysulfated glycosaminoglycan) Injectable for Horses, 100mg/mL, 50-mL vial

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Medications ship separately. Delivery times may vary.

About This Item

Details

Adequan i.m (polysulfated glycosaminoglycan) is the only FDA-approved PSGAG for degenerative joint disease (DJD) in horses. Adequan i.m. treats the disease, not just its clinical signs by reducing inflammation, restoring synovial joint lubrication, repairing joint cartilage and reversing the disease process. For over 30 years, Adequan i.m has been prescribed by veterinarians to help horses of every discipline and level enjoy greater mobility over their lifetimes. There is no generic version of Adequan i.m. Adequan i.m. (polysulfated glycosaminoglycan) is recommended for the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses.

Qualifying purchases of 7-dose series (seven 5mL vials or one 50mL vial) of Adequan Equine may be eligible for a $20 rebate. Learn how to claim your rebate in the Rebate Instructions PDF link below.

We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.

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4.9
Rated 4.9 out of 5 stars
326 Ratings
Terms & Conditions

115 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Sian on Oct 21, 2025

prolonging working life of my horse

I always know when it's time for my horse to get his next round of Adequan. We lose a little something, and gain a little head tilt as he tries to shift his weight

I always know when it's time for my horse to get his next round of Adequan. We lose a little something, and gain a little head tilt as he tries to shift his weight around. Almost from the first shot, he moves better and straighter and more powerfully. The ease it brings him is clear, and I'm a dedicated fan of the product. Friends have complained to me that the shots are expensive, but they spend more each month on supplements than I do on Adequan, and I see more difference in how my horse moves. To me, his comfort is well worth the price. He's 17 now and still progressing up the levels, but when he tells me that, even with medication, the arthritis is winning out, I'll keep him on this through his retirement so that he's as comfortable as possible until the end. It's been a game changer for us.

Rated 5 out of 5 stars
By Pamela on Nov 30, 2025

This has Really Helped My Boy!

I have been using Adequan IM injections for several years now. It really helps my sweet gelding who is 22, but his mind is 12. He loves to interact and play.

I have been using Adequan IM injections for several years now. It really helps my sweet gelding who is 22, but his mind is 12. He loves to interact and play. When his arthritis starts to act up, he gets depressed. This keeps us both in the game!

Rated 4 out of 5 stars
By Laurie on Nov 19, 2025

It’s helpful

It’s easy enough to administer (shot) and my horse tolerates both the shot and the adequan itself. He’s 21 and I don’t ride him; I just want to make him as comfortable

It’s easy enough to administer (shot) and my horse tolerates both the shot and the adequan itself. He’s 21 and I don’t ride him; I just want to make him as comfortable as possible.

Rated 5 out of 5 stars
By Penny on Nov 18, 2025

The delivery is so quick and just what I order

The adequan really seems to help our dog Lucy’s. Before her injection she is slow getting up. After the injection she gets right up. Doesn’t seem to have any side

The adequan really seems to help our dog Lucy’s. Before her injection she is slow getting up. After the injection she gets right up. Doesn’t seem to have any side effects for her

Rated 4 out of 5 stars
By Amy on Nov 17, 2025

Tried & true

I am doing the protocol where you administer every 4 days for 28 days, 7 doses total. Adequan has served my horses well, just wish they could give us all a break

I am doing the protocol where you administer every 4 days for 28 days, 7 doses total. Adequan has served my horses well, just wish they could give us all a break on the price.

Rated 5 out of 5 stars
By Sylvia on Oct 3, 2025
Top 250 Contributor

This works for my Gizmo

Gizmo does get stiff in her back legs and Adequan does keep her joints moving well. Plus I could not be happier with the cost for the Adequan at Chewy. I was paying

Gizmo does get stiff in her back legs and Adequan does keep her joints moving well. Plus I could not be happier with the cost for the Adequan at Chewy. I was paying more than $100 more from the vet in South Carolina. The vet here in New York recommended that I purchase from Chewy. So glad she allowed that.

Rated 5 out of 5 stars
By Krissy on Jan 18, 2026

After a few doses, my aged gelding was moving better

A world of difference in movement and gait for my older gelding! So glad we tried this.

A world of difference in movement and gait for my older gelding! So glad we tried this.

Rated 5 out of 5 stars
By Judith on Dec 11, 2025

Love Chewy

My orders arrive on time and super customer service! A huge thank you from me and my horse, Dan!

My orders arrive on time and super customer service! A huge thank you from me and my horse, Dan!

Rated 5 out of 5 stars
By Ginger on Dec 11, 2025

Price

I have to give Shadow an injection once a month. Chewy has the best price I have found so far.

I have to give Shadow an injection once a month. Chewy has the best price I have found so far.

Rated 1 out of 5 stars
By Neenah on Jun 30, 2025

Terribly packaged

These are 5ml glass vials that cost around $50 each and they were all just thrown together in a large plastic container. Nothing to cushion them or keep them from

These are 5ml glass vials that cost around $50 each and they were all just thrown together in a large plastic container. Nothing to cushion them or keep them from rattling around. Naturally they did not ship well. One of the vials arrived broken, so the other vials were covered in medicine and shards of glass. I did contact customer service and explained and they replaced the broken one for free which I sincerely appreciated but the replacement was packaged the exact same way!