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Most prescriptions are delivered within 3-5 days.Canalevia-CA1 (Crofelemer delayed-release tablets) is an antidiarrheal, enteric-coated drug product indicated for the treatment of chemotherapy-induced diarrhea in dogs. Crofelemer inhibits the hypersecretion of Cl- in diarrhea and normalizes the fluid influx into the GI tract. The mechanism of action in the dog has not been fully characterized. A reasonable expectation of effectiveness may be demonstrated based on evidence from published literature. Canalevia-CA1 is conditionally approved pending a full demonstration of effectiveness. Additional information for Conditional Approvals can be found at www.fda.gov/animalca.
Item Number | 741990 |
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Administration Form | Oral |
For Use With | Dogs |
Generic Name | Crofelemer |
Product Form | Tablet |
Health Condition | Diarrhea |
Chemotherapy-induced diarrhea in dogs
Decreased appetite, decreased activity, dehydration, abdominal pain, vomiting (See PI for full prescribing info).
No known food or drug-to-drug interactions.
Contraindications: Do not use in patients with a known hypersensitivity to crofelemer.
Warnings: Not for use in humans. Keep this and all medications out of reach of children. Consult a physician in case of accidental ingestion by humans. Keep Canalevia-CA1 in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
Precautions: The safe use of Canalevia-CA1 has not been evaluated in dogs that are pregnant, lactating, or intended for breeding. Prior to using Canalevia-CA1, rule out infectious etiologies of diarrhea. Prescribing Canalevia-CA1 to dogs with diarrhea secondary to infections etiologies may delay appropriate treatment.
Crofelemer
Administer 1 tablet orally twice daily for 3 days for dogs weighing ≤ 140 pounds. Administer 2 tablets orally twice daily for 3 days for dogs weighing > 140 pounds. Tablets should not be broken, crushed, or chewed. If the tablet is chewed, one additional dose may be administered. Give with or without food.
Store at 68 F to 77 F