Comfortis Chewable Tablet for Dogs, 10.1-20 lbs, & Cats, 6.1-12 lbs, (Orange Box)

By Comfortis
Rated 4.1529 out of 5 stars
Prescription Item

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$108.99Chewy Price
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Usually arrives in 3-5 days
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About This Item


Comfortis is a chewable medication prescribed by veterinarians for dogs and cats to help treat — and possibly even prevent — flea infestations for up to one month. These flavored tablets can be added to your pet's favorite food and only need to be given to your canine companion once a month to help combat fleas.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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ReviewsWrite a Review

Rated 4.1529 out of 5 stars
157 Ratings
Would recommend to a friend

157 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By SmartMule on Sep 19, 2023

Chewable? NOT!

I have to have an oral solution for one of my cats. I used to give her Program -- ground it with a pill grinder, put in food, gone. THIS STUFF SMELLS MEDICINAL THE MINUTE YOU OPEN THE PACKAGE -- not even medicinal, like some off, artificial odor. Still, didn't try to mix all in at one time, just about a fifth of the tablet. Cat won't touch it. I finally got her to eat some of it by putting yeast flakes on top of the foo. I will never buy this product again -- false advertising to list this as chewable for cats -- heck, it's not even edible!!

Rated 1 out of 5 stars
By Rachael on Aug 8, 2023

Be careful

Bought a 6 month supply. I gave my sweet baby just one of the pills (half one day in a gel cap and half the next day same way) but he had the worst reaction ever. Vomiting, pain, rapid breathing and dehydration. Please talk to your vet and make sure your baby can handle these pills. I hear they work great but my Lil Bit was extremely sick it, requiring multiple emergency vet visits and treatments to get him to being able to eat, drink and breathe normally again. After a week, he is starting to eat on his own (he's been syringe fed for days) he is getting better, but we dont know the extent of the damage yet. I will never use these again.

Rated 5 out of 5 stars
By Comfortis on Jul 17, 2023

This works! However…

I gave this to my cat after the topical meds were causing her to have an allergic reaction. I say however, because the first time she took it she vomited and salivated uncontrollably. This is said to be one of the side effects. I have medication I take for my upset stomach called Zofran so I called my vet to see if I could give that to her when I administer the medication. He said it was safe so next time I tried it and voila! No more upset tummy! She was on this for 2 years until COVID made it unavailable and I had to start using Credelio (also great)!

Rated 5 out of 5 stars
By Cindy on Aug 1, 2023


I love this product for my cats. It's the only thing that works to get rid of their fleas. Topical flea treatment just doesn't work for us. I am so glad Chewy is carrying this again because my cats were miserable when we couldn't get it. I do have to crush it and hide it in a really fishy smelling wet food to get them to eat it but that's ok. Chewy please keep making this available for purchase.

Rated 4 out of 5 stars
By IwantOneMonthOnlynotSix on Aug 27, 2023

They haven't had this product in MONTHS. Now its finally back and they want you to buy a 6 MONTH SUPPLY, WHY?? Why cant i just buy 1 month. I don't need all that. It works better than any of the other flea pills I've used but thats ridiculous

Rated 2 out of 5 stars
By cass23 on Apr 28, 2023

not for picky eaters

Spent the $100 as my vet said this would be a great alternative to topical since my cat is allergic to topical and is suffering from previous flea bites (that she is also allergic to). After reading reviews I our hard a pill crusher and mixed the equivalent of half a pill in powder form in with my cats canned food just to see if she would tolerate it as I was weary of it upsetting her stomach. She ate the food until she must have picked up on the taste of the powder. Immediately stopped eating and won’t touch her bowl. I tried giving her the rest of the powder by hand feeding her gravy and she won’t go near it at all. I’m hoping the little bit she MIGHT have consumed helps her itching? But I’m not sure she ate any of pill powder at all so this might have been a waste.

Rated 5 out of 5 stars
By Snusan on Jun 10, 2023

The only flea medicine that really works. I only give it to my dog when she gets fleas, which is about twice a year, so one box lasts 3 years.

Rated 1 out of 5 stars
By Farmer on Apr 3, 2023

Sickness is auto automatic

We gave this to two of the three of our cats and they don't normally get sick, but this got them throwing up most of the night. Luckily we didn't give it to our cat with a sensitive stomach. The size of the pill is ridiculous if they don't eat it and you have to give it to them!

Rated 5 out of 5 stars
By PupHut on Mar 12, 2023


Comfortis works purrfectly. However another one of my dogs will be taking this as the intended doggy will not eat it. These tablets are a little big. Breaking them up causes the flavor to increase. The 17 year dog is extremely picky about everything. Is a great product tho and always killed very flea dead as a door nail. The other doggy ate it. No issue. Thanks Again Chewy!

Rated 1 out of 5 stars
By kelseyk09 on Mar 28, 2023

Cat was very sick

My cat was vomiting and had diarrhea for several days after taking first dosage. Had to get her on special food to get her back to normal. Do not recommend.