Credelio Quattro Chewable Tablets for Dogs, 25.1-50 lbs, 1 Chewable (1-mo. supply)

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About This Item

Details

  • Credelio Quattro: The broadest1 parasite protection of its kind covering 6 types of parasites, including ticks, in one chewable tablet.
1

Based on label comparison of the number of parasite types covered in an isoxazoline endectocide. - This monthly flea and tick treatment also protects against heartworm disease and three intestinal worms that can be passed to humans – roundworms, hookworms† and tapeworms † Uncinaria stenocephala - Easy-to-Give Chewable: This FDA-approved parasite protection comes in a flavored chewable tablet that is given once a month with food or within 30 minutes of a meal. - Prescription Only: Credelio Quattro is a prescription medication for puppies and dogs at least 8 weeks old and weighing at least 3.3 lbs.

Ingredients

Instructions

FAQ

Get 6-in-1 Parasite Protection

Introducing Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) for dogs, a prescription medication that protects your dog from common parasites. Unlike other chewables, Credellio Quattro protects against 6 types of parasites, including ticks, fleas, heartworm disease and three intestinal worms that can be passed to humans – 3 species of tapeworms, roundworms and hookworms.

Protection in a Tasty Chewable

Credelio Quattro combines convenience with flavor. A beef-flavored, once-monthly tablet that makes it easy to administer. Enjoy peace of mind knowing your dog’s protection is effective and easy to give.

The Power of Four

Credelio Quattro features four tried and true active ingredients designed to combat parasites effectively. With lotilaner, moxidectin, pyrantel and praziquantel, this advanced formula provides your pet with the broadest parasite protection of its kind based on label comparison of the number of parasite types covered.

Shown To Be Safe for Dogs and Puppies

Use Credelio Quattro to help protect your dog proactively before problems happen. This preventive treatment is shown to be safe for puppies as young as 8 weeks old and weighing at least 3.3 lbs.

About Credelio Quattro

Prescription only. Ask your veterinarian if Credelio Quattro is right for your dog.

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Indications

Credelio Quattro is indicated for the prevention of heartworm disease and the treatment and control of roundworm, hookworm, and tapeworm infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations for 1 month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.

Important Safety Information

Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. For complete safety information, please see the Credelio Quattro product label or ask your veterinarian.

4.6
Rated 4.6 out of 5 stars
246 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

79% Positive

Effectiveness

85% Positive

Ingredients

84% Positive

Long-Term Benefits

80% Positive

63 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 4 out of 5 stars
By Madonna on Dec 29, 2025

Possible Reaction to this

We have 2 Two year old Shibas and the smaller one had a horrible allergic reaction shortly after switching to this med. It took months for him to look like normal

We have 2 Two year old Shibas and the smaller one had a horrible allergic reaction shortly after switching to this med. It took months for him to look like normal again. Itching, turned black around eyes and snout. Scratched hair off legs and his behind. Vet swears it couldn't be the med, but Im not trying it again. Went back to heart guard and NEXT GUARD.


Rated 5 out of 5 stars
By Mindy on Jan 13, 2026

Easier to use

My dog hates taking any kind of pills or meds so just having to manage one of them is much easier. He has not had any issues at all so hopefully this will be his

My dog hates taking any kind of pills or meds so just having to manage one of them is much easier. He has not had any issues at all so hopefully this will be his go to monthly preventative. So glad they made one pill.


Rated 5 out of 5 stars
By Patrice on Nov 21, 2025

Covers 4 parasites

One time use because it also covers tape worms. I don’t think I will give a second time since tape worms are not a common problem. And I don’t know what long term

One time use because it also covers tape worms. I don’t think I will give a second time since tape worms are not a common problem. And I don’t know what long term side effects the extra chemicals may cause. Easy to give. I wish chewy would allow digital transmission of prescription.


Rated 2 out of 5 stars
By Katrina on Dec 24, 2025

Large Pill

I’m sure the product works great, but it was very hard to get my dog to eat it. Large size made it hard to hide in food. Absolutely switching to something else.

I’m sure the product works great, but it was very hard to get my dog to eat it. Large size made it hard to hide in food. Absolutely switching to something else.


Rated 4 out of 5 stars
By Valerie on Nov 25, 2025

Good deal

I like this product and the 3 in 1 aspect it is more affordable than buying each separately. However, it’s a big pill that my dog doesn’t like so I have to hide

I like this product and the 3 in 1 aspect it is more affordable than buying each separately. However, it’s a big pill that my dog doesn’t like so I have to hide in a piece of cheese.


Rated 5 out of 5 stars
By Teresa on Dec 4, 2025

Ordering pills for my dog

It was pretty easy to do, you guys handled everything on your end and contacted my doctors office. It was perfect medicine came as quickly.

It was pretty easy to do, you guys handled everything on your end and contacted my doctors office. It was perfect medicine came as quickly.


Rated 5 out of 5 stars
By Peggy on Dec 5, 2025

It covers all the parasites needed to keep my pup healthy

No problems, no reactions from my pup. The tablets are large and hard, so we have to chop in smaller pieces for him to eat it.

No problems, no reactions from my pup. The tablets are large and hard, so we have to chop in smaller pieces for him to eat it.


Rated 5 out of 5 stars
By Laetitia on Nov 23, 2025

2 in 1 tablet

The cheapest version for both the anti worm and anti-flea when you have a puppy and cannot buy on the long term because of the weight change.

The cheapest version for both the anti worm and anti-flea when you have a puppy and cannot buy on the long term because of the weight change.


Rated 5 out of 5 stars
By Gregory on Dec 20, 2025

Works as advertised

My guy will NOT chew. I can't even hide them in is bowl. I wrap in hard salami after cutting in 4 pieces.

My guy will NOT chew. I can't even hide them in is bowl. I wrap in hard salami after cutting in 4 pieces.


Rated 5 out of 5 stars
By Donna on Dec 21, 2025

Fast shipment, great service checking with my vet.

This products protects for both fleas and ticks and no side effects for my herding breed dog.

This products protects for both fleas and ticks and no side effects for my herding breed dog.