Methylprednisolone (Generic) Tablets for Dogs & Cats, slide 1 of 1

Methylprednisolone (Generic) Tablets for Dogs & Cats, 4-mg, 1 tablet

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Methylprednisolone is an oral medication prescribed by vets to help treat a variety of conditions in dogs and cats. This anti-inflammatory agent is used to treat certain skin conditions, allergies and arthritis, as well as diseases including Addison’s Disease. This medication comes in an uncoated oral tablet form, making it especially easy to disguise in your dog or cat's favorite food. Customers may receive this drug under the names Depo-Medrol, Medrol.

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Methylprednisolone is formulated to help treat certain skin conditions, allergies and arthritis. It may also be used to help suppress the immune system.

Possible Side Effects

Possible side effects may include increased drinking, urination and appetite. Other side effects, which are less common may also include panting, vomiting, diarrhea, weight gain and changes in behavior. Cataracts and glaucoma have also been reported but are very rare.

Drug & Food Interactions

Before using methylprednisolone, tell your veterinarian if your pet is taking any other medication, vitamins, supplements, or non-steroidal anti-inflammatory drugs. Some of these include asprin, caprofen (Novox or Rimadyl), deracoxib (Deramaxx), etodolac (EtoGesic), tepoxalin (Zubrin), firocoxib (Previcox) or meloxicam (Metacam).


While taking methylprednisolone, immune system suppression may occur at high doses, making your pet more susceptible to infection. Contact your veterinarian if your pet has a fever over 103° F, painful urination (a sign of urinary tract infection), tiredness, sneezing, coughing, or runny eyes.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Please note product may arrive in a Chewy Pharmacy vial.

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  1. Prescribing Information

See all items by Methylprednisolone

  • Item Number
  • Generic Name
  • Common Brand Name(s)
    Depo-Medrol, Medrol
  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
    Allergies, Cancer, Addison's Disease, Joint Pain/Arthritis
  • Drug Type
    Anti-inflammatory, Immunosuppressant


Recommended Dosage

Give this medication as directed by your veterinarian. Do not stop this medication or change your pet's dosage without permission from your veterinarian.

Storage Instructions

Store at controlled room temperatures between 68° - 77°F.


What is Methylprednisolone?

Methylprednisolone is a medication used to treat certain allergies, skin conditions, and arthritis. It can also be used to suppress the immune system.

What are the benefits of Methylprednisolone?

  • Easy to administer .
  • Fast acting .

How is this medication given?

Methylprednisolone is an oral tablet, given by mouth. It may be given with food to avoid stomach upset. Always follow the dosage instructions provided by your veterinarian. If you have difficulties giving the medication, contact your veterinarian.

How does this medication work? Methylprednisolone has an effect on virtually every organ system in the body. Methylprednisolone is a corticosteroid that blocks the production of substances that trigger allergic and inflammatory actions. Methylprednisolone is used to modify the body's immune response. At lower doses it helps to reduce inflammation by decreasing the activity of certain cells and chemicals produced by the body that cause inflammation. At higher doses, it can suppress the immune system by decreasing the number of cells necessary for a proper immune response.

What results can I expect?

When used to treat inflammatory conditions, such as certain skin diseases, the success rate is usually good and improvements can be seen in several days. If the methylprednisolone is stopped, signs of the disease may reappear.

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  • 3 out of 5 stars

    Packaging problem

    By Pred on Oct 13, 2021

    Shipping box was intact, but the pill bottle was crushed, pulls scattered in the box. We were not able to find all of the pills. A ticket was opened for the pharmacy to look into the issue, but we never heard anything back.

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