Cefpodoxime Proxetil (Generic) Tablets for Dogs

Prescription Item

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Strength: 200-mg
  • 100-mg In stock
  • 200-mg In stock
Count: 1 tablet
  • 1 tablet In stock

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Cefpodoxime Proxetil is a prescription medication for dogs to treat bacterial infections of the skin including wounds and abscesses, as well as bladder and respiratory infections. Plus, since this medication comes in an oral tablet form, it can be easily disguised in your dog’s favorite food. Customers may receive this drug under the names Simplicef, Vantin.


Cefpodoxime Proxetil Tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs.

Possible Side Effects

Stop administering and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash; or fainting), severe nausea, vomiting or diarrhea, mucus or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea, diarrhea, or yeast infection may be more likely to occur.

Drug & Food Interactions

Do not give medication at the same time as giving antacids such as Maalox or other stomach acid reducers such as Tagamet.


As with other cephalosporins, cefpodoxime proxetil may occasionally induce a positive direct Coombs’ test.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Customers may receive the same drug under the names Simplicef, Vantin.

  1. Prescribing Information

See all items by Cefpodoxime

  • Item Number
  • Brand


  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Generic Name

    Cefpodoxime Proxetil

  • Common Brand Name(s)

    Simplicef, Vantin

  • For Use With


  • Product Form


  • Health Condition

    Wounds, Respiratory Infections, Urinary Tract Infections (UTI), Skin Infections

  • Drug Type



Cefpodoxime Proxetil.

Recommended Dosage

Give this medication by mouth according to a veterinarian's instructions as they will be able to determine the dose and frequency best suitable for your dog.

Storage Instructions

Store at controlled room temperatures between 68° - 77°F. Replace cap securely after each opening.


What is Cefpodoxime proxetil?

Cefpodoxime proxetil is an oral cephalosporin antibiotic used to treat bacterial infections of the skin, such as wounds and abscesses as well as bladder and respiratory infections in dogs.

What are the benefits of Cefpodoxime Proxetil Tablets?

  • Treats bacterial skin, bladder and respiratory infections in dogs .
  • Simple oral once-daily dosing.
  • Comes in a film-coated tablet for easy administration.

How is this medication given?

Give this medication exactly as directed by your veterinarian. The usual dose of cefpodoxime proxetil in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days up to a maximum of 28 days.

How does this medication work?

It is a cephalosporin antibiotic that treats bacterial infections by suppressing the growth of micro-organisms such as bacteria, fungi, or protozoa.

Customer Reviews
4 Reviews 4 Reviews 4.2 out of 5 Stars

75% Recommend

75% of reviewersrecommend this product

4.2 / 5

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  • Amazing for skin infections

    By on

    I have a white American Bulldog mix that gets terrible seasonal skin allergies and skin infections. This clears it up perfectly! It also saved me over $60 by getting this generic version of simplicef rather than getting it from the vet. They even call the vet for you! How much easier could it get?

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  • Affordable, yet still effective.

    By on

    Although, the shipping of the product was delayed by 4 days the medication for my pooch ailment has subsided. She back to her well trained/ housebroken self. Need to place an order for the last 7 dosages.

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  • perfect for my pug

    By on

    Refiling this prescription was easy. Chewy contacted vet and meds were sent to me right away. Saved me some time and travels to the vet pharmacy. This med work well for my pug's respiratory problem

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  • Generic not the real deal

    By on

    These did not clear up the problem, so back to the vet.

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