Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog Mousse, 5.1-oz bottle

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About This Item

Details

  • Mousse soothes, cleans and strengthens irritated skin for dogs.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.
  • Helps restore the balance of protective microbes.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

Ingredients

Instructions

Dermatological Treatment for Skin Issues

Developed with veterinary dermatologists, Douxo S3 offers expert solutions for pets with skin issues. The range includes shampoos, mousses, and pads—designed for daily use and to meet specific skin needs.

Made to Manage Common Skin Conditions

Douxo S3 is made to help manage common skin conditions like allergies, yeast or bacterial overgrowth, and seborrhea. Free from sulfates, parabens, colorants, and silicones, it’s pH-adjusted, soap-free, and hypoallergenic.

Featuring High-Performing Ingredients

 All Douxo S3 formulas contain Ophytrium, a natural-origin, triple-action ingredient that soothes, rebalances and strengthens the skin barrier. Other high-quality ingredients are selected to provide specific benefits in each formula. 

Easy Care for Pleasant Moments

Douxo S3 is designed to make every routine more pleasant for pets and people, with delightful textures and scents and ergonomic packaging. Co-developed with pet parents, it offers a complete skincare solution that’s easy and enjoyable to use.

About Douxo

Backed by 20+ years of expertise in veterinary dermatology, Douxo is designed to make grooming a better experience for both you and your pets.            

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Questions & Answers

26 Customer Questions

Do I also have to use it with shampoo?

Answer by Chewy • Nov 20, 2025
Use Douxo S3 PYO shampoo to clean the skin if needed.

Can I use this after conditioner?

what will happen if my dog licks it off? Is it harmful to her? She licks the salve off when I put that on her paws so I have a feeling she’ll like this off to.

Answer by Chewy • Aug 04, 2021
The Douxo products are non-toxic. If the product is ingested it can have a bad taste to it, so you may see a taste reaction due to that.

Can I use on cat?

Answer by Chewy • May 04, 2022
This mousse is designed for use on dogs only.
Reviews
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4.7
Rated 4.7 out of 5 stars
1785 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

91% Positive

Effectiveness

91% Positive

Ingredients

91% Positive

Long-Term Benefits

91% Positive

553 Customer Reviews

Rated 5 out of 5 stars
By Rebecca on Feb 8, 2026

Game changer

My dog has struggled her whole life with irritated red itchy legs to the point that she was biting off her fur and making herself bleed. I tried everything and nothing

My dog has struggled her whole life with irritated red itchy legs to the point that she was biting off her fur and making herself bleed. I tried everything and nothing helped. Her vet suggested I try using this and the pink one alternating days once a day and her skin is healing and is not extremely red and she hasn’t been as itchy! I will be buying this over and over again

Rated 5 out of 5 stars
By Taylor on Feb 10, 2026

This works on our Basset Hounds.

We use this as a three-times-a-week treatment on trouble areas that tend to get yeast infections. For our basset hounds, that’s usually under the arms, under the

We use this as a three-times-a-week treatment on trouble areas that tend to get yeast infections. For our basset hounds, that’s usually under the arms, under the chin, and between the toes. It works really well and helps keep the yeast under control.

Rated 3 out of 5 stars
By Margie on Feb 1, 2026

Douxo S3 mousse

I'd heard great things about this product, even the vet recommended it but it didn't do that much for my dog. Stopped the itch for a couple of hours that was it

I'd heard great things about this product, even the vet recommended it but it didn't do that much for my dog. Stopped the itch for a couple of hours that was it. Won't bother buying again.

Rated 5 out of 5 stars
By Theresa on Jan 31, 2026

How fast it worked

My Harley was a terrible mess with sores all over his body and paws were raw between toes. ONE day of using this he was clearing up. Two weeks usage he’s cleared

My Harley was a terrible mess with sores all over his body and paws were raw between toes. ONE day of using this he was clearing up. Two weeks usage he’s cleared completely. Amazing!

Rated 5 out of 5 stars
By Glennita on Dec 30, 2025

This product was prescribed by our vet & worked.

My shih tzu had a terrible skin problem that I had taken her to our vet for for about a yr so found dog dermatologist who prescribed this along with the same brand

My shih tzu had a terrible skin problem that I had taken her to our vet for for about a yr so found dog dermatologist who prescribed this along with the same brand shampoo and her skin cleared up. It is expensive unless it is the only thing that seems to work on your dog.

Rated 5 out of 5 stars
By Jane on Jan 5, 2026

Best shampoo for allergies

Our English Bulldog is allergic to everything. He takes both monthly and daily allergy meds, and we bathe them once a week with the shampoo. It has been a game changer

Our English Bulldog is allergic to everything. He takes both monthly and daily allergy meds, and we bathe them once a week with the shampoo. It has been a game changer for him. His skin and fur looks great..

Rated 5 out of 5 stars
By Jennifer on Jan 8, 2026

Yeasty girl no more!

This stuff is amazing. She has yeasty skin 25/8 but doesnt really need antibiotics - i use this on her paws and her abdomen and it really makes a difference! No

This stuff is amazing. She has yeasty skin 25/8 but doesnt really need antibiotics - i use this on her paws and her abdomen and it really makes a difference! No more late night toe beans being chewed on

Rated 5 out of 5 stars
By Maria on Jan 8, 2026

It really work

My coconut he his allergies tend to have him bite his paws, or little spot like rashes appear in his body and it itches a lot, so once you put the foam in the affected

My coconut he his allergies tend to have him bite his paws, or little spot like rashes appear in his body and it itches a lot, so once you put the foam in the affected areas the rashes go away

Rated 1 out of 5 stars
By Renee on Dec 27, 2025

Makes my dog hair hard

I used this on my dog and it made his fur stiff and my hands super sticky. I did get the same brand but the green one for my dog abd it made her fur so soft and

I used this on my dog and it made his fur stiff and my hands super sticky. I did get the same brand but the green one for my dog abd it made her fur so soft and was so light I enjoyed using it. This one however I did not.

Rated 5 out of 5 stars
By pura on Dec 14, 2025

Itch No More

This mousse works well if your furmate is suffering from a skin issue. Of course, my little guy went to the vet first to rule out any other issues that may be causing

This mousse works well if your furmate is suffering from a skin issue. Of course, my little guy went to the vet first to rule out any other issues that may be causing skin irritation. My vet recommended Douxo S3, and it has reduced the itching. Happy.