Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Shampoo

By Douxo S3
Rated 4.234 out of 5 stars
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Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Shampoo, 16.9-oz bottle slide 1 of 7
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Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Shampoo, 16.9-oz bottle slide 1 of 7

$36.95Chewy Price
$41.99Chewy Price
$35.10Autoship Price
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Frequently Bought Together

This Item - Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Shampoo, 16.9-oz bottle
Rated 4.234 out of 5 stars
$36.95Chewy Price
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog Mousse, 5.1-oz bottle
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Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count
Rated 4.7297 out of 5 stars
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Total Price: $0.00

About This Item

  • Shampoo soothes, cleans and strengthens irritated skin for dogs and cats.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.
  • Helps restore the balance of protective microbes.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

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Top IngredientsOphytrium, ChlorhexidineActive Ingredients: Chlorhexidine Gluconate: 2%, Ketoconazole: 1%., Inactive Ingredients: Water...Ophytrium, SebolianceActive Ingredients: Benzoyl Peroxide 3%, Sulfur 2%, Salicylic Acid 2%
Health FeatureItch & Redness Remedy, Skin & Coat Health, Anti-Fungal / Anti-Bacterial...

Questions & Answers

4 Customer Questions

What is the difference between this formula and the PS formula?
Answer by ChewyAug 25, 2021
The Douxo S3 Pyo has replaced the Douxo Chlorhexidine products. One of the main ingredients in the Douxo line, Phytospingosine, has been replaced by a combination of ingredients called Ophytrium. Ophytrium helps supports the skin's physical barrier, helps support the microbial flora of healthy skin, and helps sooth red, itchy, and irritated skin.

How often can I Shampoo my dog with this shampoo
Answer by ChewyOct 29, 2021
This shampoo should be used as recommended by your veterinarian. Shampoo amount can be doubled for dogs or cats with long and/or thick fur.

Can I use doucos3 SHAMPOO on my kitten (18 weeks old)and has tested positive for ringworm but no lesions (lesions gone but still positive)
Answer by ChewySep 15, 2021
There is no age requirement for this shampoo, it is suitable for cats and dogs of all ages. Please reach out to your veterinarian as they know your pet and what is the best for your situation.

will this shampoo wash away the flee and tick medication?
Answer by ChewyApr 02, 2022
There are no known contraindications to using Douxo S3 and antiparasitic spot on medication products at the same time. However, we recommend applying the spot-on after bathing your pet.

ReviewsWrite a Review

Rated 4.234 out of 5 stars
47 Reviews
Would recommend to a friend

47 Customer Reviews

Rated 5 out of 5 stars
By Excellent on Jun 13, 2022

Highly recommend

My dog has color dilution alopecia and contact dermatitis. This is by far the best shampoo product we have used. It doesn’t leave her skin dry, her fur is soft, and her itching decreases almost immediately.

Rated 1 out of 5 stars
By Sher on Apr 10, 2022


Disappointed With the pump does not work properly. Your old container was better pump needs to be higher more space just a very poor design!! Very unhappy with your changes..the product is a good.. but the pump is very lousy and does not operate any good at all!!! I wish that you would have never changed it it was just fine before!!! Very very very very very very very very very very very very very disappointed disappointed disappointed disappointed with your product

Rated 5 out of 5 stars
By pcon227 on Jun 30, 2022

Great Shampoo for sensitive skin!

This was recommended by our dog's Dermatologist and has been working well! Itching is minimal and there's no perfumey smell. Win-Win!

Rated 4 out of 5 stars
By Mookie on Jun 30, 2022

The Douxo S3 seems to have help with Mookie’s itching

I think the Douxo S3 is actually helping with Mookie’s itching he’s not chewing on himself as often and it makes him smell better too!

Rated 5 out of 5 stars
By DogMa on Mar 20, 2022

Great Product!

My dog had bumps all over her back that had not been controlled by medications or other medicated shampoos. This shampoo has been the only product I have found that controls her skin issues. It does work better used weekly. I have no problem with the scent, it's not overwhelming or unpleasant. The only con I've found is the pump is hard to use. Maybe because the dispenser doesn't sit very high from the bottle or because the shampoo is thick, I'm not sure. Otherwise a great product!

Rated 5 out of 5 stars
By tatersmom on Jul 2, 2022

Shampoo for tater

This shampoo is wonderful for my girl! She has great hair and skin now! I wish you carried the skin spray too !

Rated 5 out of 5 stars
By Hotspotdisaster on Apr 11, 2022

It's a wonderful product

Have a Labrador who breaks out in the worst hot spots around his tail and butt. Have tried many things but this shampoo after 3 uses he's not licking or itching like crazy. His hair is starting to grow back. Such a relief to find him relief Thank God for this product!!

Rated 2 out of 5 stars
By MudHen on Feb 20, 2022

Sent Change

I loved this product before the latest bottle and was very happy to see the helpful pump bottle. The previous version of this shampoo had a nice, light scent. This last one has an overpowering scent. I’m not sure why a change was made, particularly in a shampoo for dogs with skin issues. I had noticed the same odor but even stronger in the Duoxo wipes. I used one of those and threw the remainder in the trash after washing the dog's feet to remove the smell. Much as I liked the previous version of shampoo, I will look for another option. Having to toss a $37 bottle of shampoo and $15 for wipes has been an expensive and disappointing purchase.

Rated 5 out of 5 stars
By Lola on May 27, 2022

Shampoo is great

Tried other shampoos to clear up a skin staff infection on my big ole dog this one helped him tremendously

Rated 4 out of 5 stars
By clmurphy on Jan 31, 2022

Need a bigger size

I have a 63 lb. dog and I only get about six (6) washes out of this small size. What ever happened to the big bottles of dog shampoo? Regardless if they're for dogs with skin allergies or not, I need a much bigger bottle. It does help him not itch so much, but he's still red. I have to wash him at least every two weeks so he doesn't stink so bad.