Douxo S3 SEB Odor-Control Seboregulating Dog & Cat Shampoo, 16.9-fl oz bottle

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$38.99 Chewy Price
($2.31 /fl oz)
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About This Item

Details

  • Shampoo for dogs and cats helps remove excess sebum, oils and flaky skin buildup.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.
  • Helps restore the balance of protective microbes.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

Ingredients

Instructions

Related to This Item

Dermatological Treatment for Skin Issues

Developed with veterinary dermatologists, Douxo S3 offers expert solutions for pets with skin issues. The range includes shampoos, mousses, and pads—designed for daily use and to meet specific skin needs.

Made to Manage Common Skin Conditions

Douxo S3 is made to help manage common skin conditions like allergies, yeast or bacterial overgrowth, and seborrhea. Free from sulfates, parabens, colorants, and silicones, it’s pH-adjusted, soap-free, and hypoallergenic.

Featuring High-Performing Ingredients

 All Douxo S3 formulas contain Ophytrium, a natural-origin, triple-action ingredient that soothes, rebalances and strengthens the skin barrier. Other high-quality ingredients are selected to provide specific benefits in each formula. 

Easy Care for Pleasant Moments

Douxo S3 is designed to make every routine more pleasant for pets and people, with delightful textures and scents and ergonomic packaging. Co-developed with pet parents, it offers a complete skincare solution that’s easy and enjoyable to use.

About Douxo

Backed by 20+ years of expertise in veterinary dermatology, Douxo is designed to make grooming a better experience for both you and your pets.            

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Lifestage           
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages, Adult
All Lifestages
All Lifestages, Adult
Ingredients           
Ophytrium, Seboliance
ACTIVE INGREDIENT: Ophytrium 0.75%, INACTIVE INGREDIENTS:Water, cocamidopropyl hydroxysultaine, sodium methyl lauroyl isethionate, sodium methyl
Ophytrium, Chlorhexidine
Active Ingredients: 2% Miconazole Nitrate USP, 2% Chlorhexidine Gluconate USP, USP tris-EDTA.
Active Ingredients: Benzoyl Peroxide 3%, Inactive Ingredients: Water, Sodium C14-16 Olefin Sulfonate, Propylene Glycol, Acrylates Copolymer, Sulfur,
Also contains: lauramine oxide, cocamidopropyl betaine, decyl glucoside, tetrasodium EDTA, fragrance.
Chelated Silver, Stannous Fluoride, Sodium Lauryl Sulfate, Zinc Gluconate, Hamposyl L-30, Tergitol, Glycerine, Fragrance. Smell Terrific Citrus and
Active Ingredients: Chloroxylenol 2%, Salicylic Acid 2%, Sodium Thiosulfate 2% (Source of Soluble Sulfur)., Inactive: USP Purified Water, Sodium
Active: Pramoxine Hydrochloride 1%., Inactive: USP Purified Water, Decyl Polyglucose, Cocamidopropyl Hydroxysultaine, Nm7, Cocamidopropyl Betaine,
Active: 4% Chlorhexidene Gluconate, Trizedta (Tromethamine USP, Disodium Edta Dihydrate). Also Contains: Lauramine Oxide, Cocamidopropyl Betaine,
Also Contains: Water, Decyl Polyglucoside, Cetrimonium Chloride, Laureth-12, PEG-120 Methyl Glucose Dioleate, Sodium Hydroxide, Acetic Acid.
Active Ingredients: Chlorhexidine Gluconate 2% and Ketoconazole 1%.
Health Feature           
Skin & Coat Health
Itch & Redness Remedy
Anti-Fungal / Anti-Bacterial, Skin & Coat Health
Anti-Fungal / Anti-Bacterial, Itch & Redness Remedy, Skin & Coat Health
Skin & Coat Health
Anti-Fungal / Anti-Bacterial
Anti-Fungal / Anti-Bacterial
Anti-Fungal / Anti-Bacterial, Itch & Redness Remedy, Skin & Coat Health
Sensitive Skin, Itch & Redness Remedy, Skin & Coat Health
Anti-Fungal / Anti-Bacterial, Itch & Redness Remedy, Skin & Coat Health
Anti-Fungal / Anti-Bacterial
Anti-Fungal / Anti-Bacterial
Breed Size           
All Breeds
All Breeds
All Breeds
—
All Breeds
All Breeds
All Breeds
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—
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All Breeds

Frequently bought together

Questions & Answers

3 Customer Questions

This doesn’t look like it has a complete ingredients list, I have a dog with bad allergies and need to know all ingredients… is there a way to view that before I buy?

is this good on long hair cats

Answer by Chewy • May 24, 2022
This shampoo is for dogs or cats to help manage all seborrhea types, including dry, flaky, greasy and combination skin. It can be used with any type of fur.

Is there a dilution ratio for this product?

Answer by Chewy • Sep 15, 2025
There is no dilution ratio for this shampoo. It can be used as is. Using 1 pump for every 4 lbs, gently massage shampoo onto skin abnormalities to reach the skin. Repeat until entire body is lightly coated with shampoo and leave on for 10 minutes. Rinse thoroughly with cool water. Shampoo amount can be doubled for dogs or cats with long and/or thick fur.
Reviews
Write a Review
4.6
Rated 4.6 out of 5 stars
206 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Durability

76% Positive

Ease of Use

76% Positive

Effectiveness

85% Positive

Safety

84% Positive

73 Customer Reviews

Rated 5 out of 5 stars
By Tammy on Sep 23, 2025

Great smell

My puppy has a food allergy and has to eat a prescription can and now dry food in which after a few days of her being groomed she smelled dirty like she had not

My puppy has a food allergy and has to eat a prescription can and now dry food in which after a few days of her being groomed she smelled dirty like she had not had a bath but the can food does that. My vet said to purchase this shampoo and I am 200% happy with it. She still has a good smell to her a week after getting groomed. I will continue to use this product and would recommend it to anyone who has the same issues. It works wonders!!

Rated 5 out of 5 stars
By Nadine on Aug 29, 2025

Amazing

We have a dog that has a very unfortunate smell from her sebaceous oil glands. We Barely gets three days after a bath without a stink. I’ve done so much research

We have a dog that has a very unfortunate smell from her sebaceous oil glands. We Barely gets three days after a bath without a stink. I’ve done so much research and asked everywhere and nothing worked until this. After the first use, we went a month without a bath! We were all thrilled, including our dog. We’ve used it for three consecutive months once a month, and this time we used our old regular dog shampoo to see if we could alternate and she doesn’t stink! We’re having to do so much dog bedding, the laundry was exhausting. Life just got a lot easier. and a happier dog, And owners.

Rated 4 out of 5 stars
By Jacquelin on Oct 3, 2025

Nice Lather

I was surprised that this lathered up as well as it does! Usually these type of shampoos tend to lather less. Unscented is great. Will see how it works out for my

I was surprised that this lathered up as well as it does! Usually these type of shampoos tend to lather less. Unscented is great. Will see how it works out for my SA poodle

Rated 5 out of 5 stars
By Deborah on Jul 31, 2025

Great shampoo!

My cat has severe seborrhea and we’ve been having him bathed with this shampoo. It’s really helping his appearance. It leaves his fur soft and smelling good. I hope

My cat has severe seborrhea and we’ve been having him bathed with this shampoo. It’s really helping his appearance. It leaves his fur soft and smelling good. I hope people don’t need this, but if you do, I heartily recommend it.

Rated 5 out of 5 stars
By Nicole on Sep 10, 2025

Works SO WELL

My cat has extreme dandruff and nothing can seem to tame it EXCEPT DouxoS3 and it’s matching foam! Smells great too

My cat has extreme dandruff and nothing can seem to tame it EXCEPT DouxoS3 and it’s matching foam! Smells great too

Rated 3 out of 5 stars
By Destiny on Aug 6, 2025

Dont think it works

tried this on my huskies, they still have an odor to them, maybe i need to be consistent in using the product but so far i dont think it has helped much

tried this on my huskies, they still have an odor to them, maybe i need to be consistent in using the product but so far i dont think it has helped much

Rated 4 out of 5 stars
By Bill on Aug 22, 2025

Poor application

Hard to work into a long haired dog and allowing 10 minutes to set as advised by the vet is next to impossible.

Hard to work into a long haired dog and allowing 10 minutes to set as advised by the vet is next to impossible.

Rated 4 out of 5 stars
By Carrie on Jun 30, 2025

So soft

I have only used it once, so I haven’t noticed an improvement in his flaky skin. However, two weeks later his coat is still soft and shiny.

I have only used it once, so I haven’t noticed an improvement in his flaky skin. However, two weeks later his coat is still soft and shiny.

Rated 5 out of 5 stars
By Charlotte on Oct 15, 2025

Shampoo

Healed hot spots. Hair softer. No dog smell.

Healed hot spots. Hair softer. No dog smell.

Rated 5 out of 5 stars
By Irma on Aug 11, 2025

Barbie

Hit the spot and my Bull Dog is doing a lot better with his allergies. Thank God.

Hit the spot and my Bull Dog is doing a lot better with his allergies. Thank God.