Nature's Miracle Enzymatic Formula Urine Destroyer Plus Dog Stain & Odor Remover, 1-gal bottle

Deal
Skip image gallery
Slide 1 of 10

At a Glance

  • Made in USA
  • All Lifestages

$20.59 First Time Autoship Price
this order
Save 35% today when you set up Autoship. 
$30.09 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$31.67 Chewy Price
($31.67 /gl)
Save $5.82 (-16%)
$37.49 List Price
Promo, Spend $100, Get $30 eGift Card with code NEWYEAR
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
In Stock
FREE 1-3 day delivery on first-time orders over $35
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • Starts to break down and remove dog urine stains on contact.
  • Easy to use—simply soak the affected area, allow to work for 15 minutes, then blot with a clean cloth..
  • The enzymatic formula keeps working as long as any bio-based mess is present.
  • Nature’s Miracle bottles are designed with 25% post-consumer recycled material.
  • Safe for use around your pets and home when used and stored as directed.

Ingredients

Instructions

About Nature's Miracle Stain and Odor Solutions

Trust the Miracle

Nature’s Miracle pet stain and odor removers have been a trusted choice for pet mess cleanup for over 40 years. When your pets make not-so-cute messes, you can always rely on Nature’s Miracle products to get the job done.

Solutions for the Toughest Pet Messes

Nature’s Miracle stain and odor formulas help you tackle tough pet messes like urine, feces, vomit and drool. From spot-cleaning everyday messes to eliminating stubborn stains, these solutions help you keep your home clean.

Break Down Stains on Contact

Nature’s Miracle cleaning formulas start to work the moment they come in contact with pet messes. With several targeted cleanup solutions available, you’ll find it easy to choose just the right product for your needs.

Not All Pet Messes Are the Same

Solutions for Dogs

Nature’s Miracle products for dogs are specially formulated to handle your dog’s messes. Choose from a variety of formulas tailor made to handle any canine stain or odor removal jobs that come your way.

Solutions for Cats

Cat messes and odors present their own unique challenges, and Nature’s Miracle products for cats are specially formulated to tackle them. From Urine Destroyer to enzymatic Stain & Odor Remover formulas, these products are made to get the job done.

Targeted Solutions for Life With Pets

Original Stain & Odor

The original, must-have formula made for cleaning up everyday pet messes.

Simply Nature’s Miracle

Made with 86% plant-based surfactants and essential oils for fragrance, you can feel good about using these in your home.

Urine Destroyer

These targeted formulas are made to destroy severe urine stains and odors and get rid of yellow, sticky residue.

Advanced Eliminators

Use these advanced bio-enzymatic and antibacterial formulas to eliminate the most severe pet messes.

Sprays and Gallon Sizes

Choose from a range of convenient sprays to have on hand for targeted cleanup on a variety of surfaces. The easy-to-store gallon jugs are great for refills and perfect for multi-pet homes, too.

Easy Pour

Get the right amount of solution right where you need it with this easy-pour bottle and spout.

Aerosol Foam

Penetrating aerosol foam gets deep down into carpet fibers to power out severe pet messes.

About Nature's Miracle

Cat messes and odors present their own unique challenges, and Nature’s Miracle litter box products for cats are specially formulated to tackle them. Make life with your cat a little more pleasant with these trusted litter box solutions!

Shop Nature's Miracle

Frequently bought together

Questions & Answers

10 Customer Questions

Is this product safe around cats two. ? It seems everything is for dogs more ! There is a big difference

Will this work on old urine spots?

Answer by Chewy • Mar 18, 2025
This is a suitable option for tough old urine spots.

Can this be put in a carpet cleaning machine?

Answer by Chewy • Apr 10, 2023
This stain remover is not intended for use in the carpet cleaner.

Can this be used on laminate floors for mopping?

Answer by Chewy • Mar 18, 2025
This can be used on laminated floors. It is not intended to be diluted.
Reviews
Write a Review
4.6
Rated 4.6 out of 5 stars
1405 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

89% Positive

Effectiveness

87% Positive

Safety

84% Positive

Stain Type

84% Positive

322 Customer Reviews

Rated 1 out of 5 stars
By Janette on Jan 11, 2026

Does Not Work

We just got a new puppy and needed stain and odor remover for accidents. I went with this one based on reviews and it is doing nothing to combat the odor or stains

We just got a new puppy and needed stain and odor remover for accidents. I went with this one based on reviews and it is doing nothing to combat the odor or stains. It doesn't work at all so I'm not sure why there are so many positive reviews. It is leaving marks all over my carpets, and clearly you can see yellow still and if you get close, it smells like urine. I followed all the directions to a T and now I'm left with spots all over my house in desperate need of cleaning. I do not recommend this product at all!

Rated 5 out of 5 stars
By Kathryn on Dec 26, 2025

The Gold Standard in removing urine accidents

Tucker is a rescue from a hoarding situation and has frequent accidents. This stuff is a God send -- they disappear from the rug/wood floor, leave no odor, and

Tucker is a rescue from a hoarding situation and has frequent accidents. This stuff is a God send -- they disappear from the rug/wood floor, leave no odor, and are a breeze to clean up. Thank you Nature's Miracle! I had a elderly Wheaten Terrier years ago who started having frequent accidents and we had this stuff on auto ship. It enable us to keep our carpets and our sanity.

Rated 1 out of 5 stars
By Amber on Jan 10, 2026

Alful

I bought this for my daughter. We used a small bit on carpet and the odor was so bad. It was horrible toget out of house. I also bought same kind for cushions on

I bought this for my daughter. We used a small bit on carpet and the odor was so bad. It was horrible toget out of house. I also bought same kind for cushions on sofa. It was so bad she might have to replace cushions if we can’t get it out. Have been trying for days. Do not buy!

Rated 5 out of 5 stars
By Angie on Jan 18, 2026

Works well!

Training our pups was a lot of work and they occasionally had accidents. This enzymatic formula cleaned up the messes quite well. We have not had any issues with

Training our pups was a lot of work and they occasionally had accidents. This enzymatic formula cleaned up the messes quite well. We have not had any issues with odors or stains after using this product.

Rated 5 out of 5 stars
By Warren on Nov 4, 2025

Somebody had a piddle problem!

Used this product to remove urine from an 8'x10' area rug and the hardwood floor beneath it. Needed to soak the rug in this product in the driveway, let it sit for

Used this product to remove urine from an 8'x10' area rug and the hardwood floor beneath it. Needed to soak the rug in this product in the driveway, let it sit for 24 hours, then pressure-wash and squeegee to clean and remove all stains. Dried for 48 hours, and it came out looking and smelling amazing.

Rated 5 out of 5 stars
By Kim on Dec 2, 2025

This does work

After using several different products for pet urine odors when cats have accidents near the litter box, I finally believe I found one that actually does the trick

After using several different products for pet urine odors when cats have accidents near the litter box, I finally believe I found one that actually does the trick. I've used multiple times and keep an extra bottle on hand.

Rated 2 out of 5 stars
By Jamie on Oct 22, 2025

Not impressed

While this product sometimes cleaned well, it did not deter our puppy from peeing in the same spots. After a few months of use the product stained two of our hallway

While this product sometimes cleaned well, it did not deter our puppy from peeing in the same spots. After a few months of use the product stained two of our hallway runners, which now need to be replaced. Perhaps we should have removed the rugs entirely while house training a puppy, so maybe that’s our fault, but live in a small NYC apartment so didn’t have that flexibility.

Rated 1 out of 5 stars
By Patricia on Nov 2, 2025

Wring product

These Nature's Miricle products work very well, but I am rating with 1 star because I was sent the wrong product. The agent on the phone couldn't have been nicer,

These Nature's Miricle products work very well, but I am rating with 1 star because I was sent the wrong product. The agent on the phone couldn't have been nicer, a truly lovely person, however I asked for the red bottle and was sent the white. Probably an error in the warehouse.

Rated 4 out of 5 stars
By Denise on Dec 6, 2025

Only had to use it twice

Dusty was practically 100% house broken at 10 weeks old when we got her she has had maybe 3 pee pee accidents which were our fault. We used the cleaner with suc

Dusty was practically 100% house broken at 10 weeks old when we got her she has had maybe 3 pee pee accidents which were our fault. We used the cleaner with success

Rated 1 out of 5 stars
By Michelle on Oct 15, 2025

Won’t purchase again - smells so bad

Don’t be fooled by the high reviews! This spray does not help with odors and honestly made the urine smell worse. We have an 11 week pup so I’m surprised this spray

Don’t be fooled by the high reviews! This spray does not help with odors and honestly made the urine smell worse. We have an 11 week pup so I’m surprised this spray didn’t work better neutralizing the odor. I recently switched over to Mrs. Meyers Pet Stain & Odor remover and the spray smells lovely and actually works!