PRN Pharmacal Prozyme Powder Supplement for Dog & Cats, 3-oz bottle

Deal
Skip image gallery
Slide 1 of 4

At a Glance

  • Digestive Health
  • All Lifestages
  • All Breeds

$7.05 First Time Autoship Price
this order
Save 50% (up to $20) today when you set up Autoship. 
$14.11 Autoship Price
future orders
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$14.11 Chewy Price
($4.71 /oz)
Promo, Spend $100, Get $30 eGift Card with code NEWYEAR
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
In Stock
FREE 1-3 day delivery on first-time orders over $35
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • Created and manufactured in the USA at a state-of-the-art facility using the highest-quality, holistic ingredients.
  • An all-natural combination of plant-derived digestive enzymes in a palatable powder form.
  • Convenient and affordable powder helps your dog or cat thoroughly and efficiently digest her food and support normal health.
  • Maximize your best friend's nutrition by improving her ability to absorb nutrients from her food.
  • The four included enzymes help break down protein, fat, carbohydrates and fiber; also helps address general gastrointestinal bowel concerns.

Ingredient Information

Instructions

FAQ

Frequently bought together

Questions & Answers

16 Customer Questions

Why should this be used under veterinary care....can something harmful happen?

Answer by Chewy • Jul 04, 2018
Do not use in animals with known hypersensitivity to any of the ingredients. This product is intended for intermittent or supplemental feeding only. Keep out of reach of children and pets.

Is this product free of gluten, soy, wheat, whey?

Answer by Chewy • Oct 14, 2022
For a complete list of ingredients and the guaranteed analysis, click the “Nutritional Information” tab on the product page.

How long can you have your dog use this ??

Answer by Chewy • Jan 16, 2020
ProZyme should be a part of every meal for the life of the animal.

Does this help deter coprophagia?

Answer by Chewy • May 22, 2023
This supplement is designed to thoroughly and efficiently help digest food for dogs and cats as well as support their nutritional requirements for normal health. It is not designed to treat specific diagnoses.
Reviews
Write a Review
4.6
Rated 4.6 out of 5 stars
206 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Effectiveness

92% Positive

Form and Administration

84% Positive

Ingredients

91% Positive

Nutritional Value

94% Positive

99 Customer Reviews

Rated 1 out of 5 stars
By Rachel on Jan 14, 2026

I had high hopes

Reading the reviews I hoped this would have been the answer to get my dogs diarrhea under control. After a food intolerance analysis, food change with no ingredients

Reading the reviews I hoped this would have been the answer to get my dogs diarrhea under control. After a food intolerance analysis, food change with no ingredients she is intolerant to, her diarrhea continued. Tried adding this and it seemed to have made it worse. I hope it works for others! It however did not help my dog with diarrhea (and yes I have tried probiotics however she is highly intolerant to ingredients, and metronidazole doesn't help either). Guess it's back to the vet we go.

Rated 5 out of 5 stars
By Sheri on Jan 4, 2026

Awesome product

My 14 year old dog started to eat stool, yuck I know. A little reserch and I found out older dogs may start to do that because they need their guts “good” bacteria

My 14 year old dog started to eat stool, yuck I know. A little reserch and I found out older dogs may start to do that because they need their guts “good” bacteria replenished. After only about a week of using the prozyme powder he is more active and seems more energetic. Have not noticed any more stool eating either. The powder is a bit expensive but such a small amount is used per meal, about 1/2 teaspoon per meal, the bottle will last a long time. So happy to find something that made such a big difference in a very short time. Thank you Chewy.

Rated 5 out of 5 stars
By Alison on Dec 1, 2025

Better digestion, everybody wins

A neighbor recommended this for my boxer, and it made a real difference by stopping stinky belches and smelly gas, and firming up the stool. Now I use it for my

A neighbor recommended this for my boxer, and it made a real difference by stopping stinky belches and smelly gas, and firming up the stool. Now I use it for my pit mix with equally good results and great body condition. I sprinkle it over kibble and jiggle the dish a bit to mix it around. For the extra-short faced boxer, I sprayed a little water over it to be sure she wouldn’t aspirate the powder. Pitty loves it as-is. Larger bottle contains many servings and is easy to measure from.

Rated 5 out of 5 stars
By James on Dec 20, 2025

Dog gained weight

Our dog would scarf his food, but would still look very skinny. He has had digestive issues since we’ve had him as a puppy. He’s now three years old, and we began

Our dog would scarf his food, but would still look very skinny. He has had digestive issues since we’ve had him as a puppy. He’s now three years old, and we began to add this powder to his food and he’s began to gain weight and his digestion is much better.

Rated 5 out of 5 stars
By Mark on Oct 27, 2025

Our dog has EPI

Our German Shepherd was losing significant weight and was diagnosed with Exocrine Pancreatic Insufficiency (EPI). His pancreatic function is extremely low and he

Our German Shepherd was losing significant weight and was diagnosed with Exocrine Pancreatic Insufficiency (EPI). His pancreatic function is extremely low and he was wasting away. Prozyme in conjunction with raw ground beef pancreas daily has save his life.

Rated 5 out of 5 stars
By Chrystal on Oct 24, 2025

Saw difference right away.

My vet recommended that I get this for my 12 year old American Staff Terrier. Some older dogs can be deficient in digestive enzymes and this has helped him to breakdown

My vet recommended that I get this for my 12 year old American Staff Terrier. Some older dogs can be deficient in digestive enzymes and this has helped him to breakdown his food so now he's not throwing up every day anymore.

Rated 5 out of 5 stars
By Mary on Dec 30, 2025

Great natural enzyme source.

I’ve used this for many dogs over the last 20 years. Reliable, safe healthful.

I’ve used this for many dogs over the last 20 years. Reliable, safe healthful.

Rated 1 out of 5 stars
By Heather on Jun 25, 2025
Top 500 Contributor

For some reason, no clear expiration date on the first or second bottle.

The first bottle I received had the last number of the year completely missing. The second bottle looks like the last number of the year should be a 4, but the number

The first bottle I received had the last number of the year completely missing. The second bottle looks like the last number of the year should be a 4, but the number is almost completely rubbed off. I won't give my puppy a supplement that might be expired, and it seems like I cannot get a bottle that shows the expiration date, so I would like a refund at this point. I am disappointed because when I spoke to someone in chat, the individual put a note in the system to make sure the expiration date was visible before sending, and apparently that note was ignored.

Rated 5 out of 5 stars
By Ann on Sep 13, 2025

Pancreatitis

I have a dog that was diagnosed with pancreatitis four years ago. This, along with the Hills WD Prescription Diet has kept him healthy and out of the Vets offi

I have a dog that was diagnosed with pancreatitis four years ago. This, along with the Hills WD Prescription Diet has kept him healthy and out of the Vets office.

Rated 5 out of 5 stars
By Caroline on Oct 8, 2025

It’s easy to use

Quigley’s vet recommended this product and it seems to have helped his stomach & bowel movements a lot.

Quigley’s vet recommended this product and it seems to have helped his stomach & bowel movements a lot.