Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 45 count

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At a Glance

  • Veterinary Diet
  • Calming
  • All Lifestages
$49.99 Chewy Price
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About This Item

Details

  • Veterinarian-recommended cat probiotic supplement helps support calm behavior.
  • Utilizes the special probiotic strain BL999 to help your kitty stay calm.
  • Probiotics powder helps reduce your cat’s anxious behaviors, like pacing.
  • Helps your kitty cope with changes in their routine and location, relieves cat stress, and supports positive behaviors—like playing and seeking out social contact.
  • Supports your cat’s healthy immune system and helps keep them calm by blunting cortisol, a marker of stress.

Ingredient Information

Instructions

Looking for more? Shop All Calming Aids

About Purina Pro Plan Veterinary Supplements for Cats

Supplements You Can Trust

From gastrointestinal and immune health to anxious behaviors and hydration issues, find support for your pet with Purina Pro Plan Veterinary Supplements. Trusted by veterinarians, every supplement is backed by research, including Purina’s line of probiotic supplements that represents their leadership in the field of microbiome research.

Easy to Administer

Each supplement was designed to be effective and easy to give your pet via powder sachets or liquid pouches.

Made by Experts

Pro Plan Veterinary Supplements are developed by a collaborative network of scientists, veterinarians and nutritionists.

Exceptional Quality

In a typical shift, Purina conducts 400+ quality checks on ingredients, packaging, receiving, processing, and packing.

Responsible Sourcing

Each ingredient can be traced back to its trusted supplier, so quality may be evaluated all the way back to the source.

About Purina Pro Plan Veterinary Supplements

Purina Pro Plan is committed to the health of every pet— especially those pets with unique needs. These advanced veterinary supplements are backed by decades of research and supported by a global network of scientists. Purina’s knowledge and experience continues to lay the groundwork for innovative supplements trusted by pet parents and veterinary professionals alike.

Shop Purina Pro Plan Veterinary Diets

Questions & Answers

28 Customer Questions

Is there a way to give it to my cat without her eating around it? Because I don't think she either eats the food when we put it mixed in with her wet food or she eats around it? She seems to be taking after her late sister with being picky, but not as bad.

Answer by Cherie • Oct 23, 2025
My 2 cats had different takes on this stuff. 1 eats it if in wet food, the other dry food, however she stopped eating all together now , so I'm having to stop dosing at all. And now she's showing signs of discomfort , so trying to figure out if it's this stuff or something else.

Can I give this to my pregnant cat?

how much malodextrin is in this i believe this is a toxic substance

Is this able to be used with the “FortiFlora” digestive blend, or does the probiotics in this “Calming” blend suffice by itself??

Answer by Chewy • Oct 09, 2021
FortiFlora and Calming Care utilize two different strains of bacteria, Enterococcus faecium (SF68) and Bifidobacterium longum (BL999) respectively. Different strains of probiotics have different effects on the body. The promotion of normal intestinal microflora produced through use of FortiFlora specifically targets gut health and gastrointestinal related issues, such as diarrhea. Calming Care, by contrast, communicates with the central nervous system where it has an anxiolytic effect on the pet. In other words, the benefits from FortiFlora are different from the benefits from Calming Care.
Reviews
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4.4
Rated 4.4 out of 5 stars
1626 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Effectiveness

82% Positive

Form and Administration

83% Positive

Ingredients

79% Positive

Nutritional Value

75% Positive

681 Customer Reviews

Rated 2 out of 5 stars
By GAYZE on Jan 21, 2026

My last ditch effort to have harmony amongst my cats

I have two 15-year-old cats, Matisse and Sabine, brother and sister. I introduced a kitten, Kato, into the household in November of 2024. It has been a nightmare

I have two 15-year-old cats, Matisse and Sabine, brother and sister. I introduced a kitten, Kato, into the household in November of 2024. It has been a nightmare since. Matisse and Sabine are hostile towards Kato. I tried air room diffuserd that were supposed to dispense calming pheromones. Didn't work I purchased the Purina Pro Plan supplement in addition to some "calming collars" in hopes to bring some harmony amongst the three felines. Matisse is still hostile towards Kato and there is a lot of hissing and Kato usually runs in fear. I really don't know what to do.

Rated 5 out of 5 stars
By Lori on Jan 26, 2026

This is amazing

Our cat had anxiety and was over grooming. I started mixing it into her wet food in mid-December and by mid-January she had quit grooming those spots too much and

Our cat had anxiety and was over grooming. I started mixing it into her wet food in mid-December and by mid-January she had quit grooming those spots too much and the hair has grown back. She also is relaxed enough that she’s doesn’t run when she hears a loud noise. My vet said she recommends this product. I’m going to see if she still needs the pheromone warmers. I suspect she won’t. That will save lots of money.

Rated 4 out of 5 stars
By Kathy on Jan 2, 2026

Sparks his appetite!

Our Vet recently recommended Calming Care for my 18.5 year old kitty. He has progressing kidney disease & is going to the litter box hourly. The doctor has seen

Our Vet recently recommended Calming Care for my 18.5 year old kitty. He has progressing kidney disease & is going to the litter box hourly. The doctor has seen good responses from this product for calming the cat’s stress from this illness. I just started using it & he readily eats it. If he turns away from a fresh plate of food & I sprinkle a bit of the powder he eats with no problem. This is important to maintain his weight. I’ll keep using it & see if there are additional positive effects. I also appreciate the Chewy discount with autoship.

Rated 5 out of 5 stars
By Lisa on Jan 20, 2026

Our cats LOVE Calm

Our cats love Calm (and Fortaflora) so much we use it for ‘seasoning’ when we’re transitioning foods or in the case of our kitty w/ kidney disease not wanting to

Our cats love Calm (and Fortaflora) so much we use it for ‘seasoning’ when we’re transitioning foods or in the case of our kitty w/ kidney disease not wanting to eat his bland prescription foods. I think it does help calm them too- we add to our cats food when we’re preparing to go away and have our cat sitter give it to them while we’re away. We also use it when we have house guests or before groomers visits.

Rated 3 out of 5 stars
By Melanie on Jan 3, 2026

*calmness*

I must start that NO, ZERO, ZIP cats under 2-3yrs old need to be calmed unless medically advised. If you chose to go homeo/natura pathic, that is your choice. My

I must start that NO, ZERO, ZIP cats under 2-3yrs old need to be calmed unless medically advised. If you chose to go homeo/natura pathic, that is your choice. My Bea was finally diagnosed with Feline Idiopathic Cystitis just this year. 9 fuqing years of vet bills and $$ upon $$. I had to tell her vet what I was suspecting and it's the final of all of any of usually undiagnosed disorders. So far, this hasn't helped as touted. I'll give it 2 more weeks.

Rated 3 out of 5 stars
By Matthew on Dec 19, 2025

Stopped working

We have a younger male cat that constantly bullies our senior female cat. The vet suggested trying the calming care supplement. Around the 2 month mark it seemed

We have a younger male cat that constantly bullies our senior female cat. The vet suggested trying the calming care supplement. Around the 2 month mark it seemed like he had calmed down some and was leaving her alone more than he was bullying her. Unfortunately, it didn’t last. As more time passed, we gradually started seeing him harassing her again. Now he’s back to bullying her every day. The only benefit that we noticed after he started taking the supplement that has lasted is that his fur is softer than it used to be.

Rated 2 out of 5 stars
By Sharon on Dec 11, 2025

Carrageenan a big no-no

My very picky cat walked away from this. We keep trying to slowly introduce different brands with zero success. She's a 6 year old rescue with no history, so don't

My very picky cat walked away from this. We keep trying to slowly introduce different brands with zero success. She's a 6 year old rescue with no history, so don't know what she ate previously. Shelter had her on dry Purina Pro Plan, so she eats that but I prefer a healthy wet food. She ate Frisky Gems (also not great) for a day but no more. This brand also has carrageenan which is really bad. So more going in the donation bin. I'll post again if we ever find Molly's Holy Grail Food.

Rated 3 out of 5 stars
By Pet Guardian on Dec 23, 2025

Fingers crossed

The vet recommended this for my cat who has been overgrooming and losing weight. Her blood work came back fine, her massive appetite is unchanged and increased food

The vet recommended this for my cat who has been overgrooming and losing weight. Her blood work came back fine, her massive appetite is unchanged and increased food portions recently, so they said she's probably stressed. This product takes 30 days to take effect and it's only been two weeks, so not able to determine if it's helping her stress.

Rated 1 out of 5 stars
By Jeanette on Dec 6, 2025

Wanted to try this formula but

Packets damaged powder formed a sheet must have retained moisture when packed at purnia. I Reported this to chewy customer service. Unfortunately, the girl was not

Packets damaged powder formed a sheet must have retained moisture when packed at purnia. I Reported this to chewy customer service. Unfortunately, the girl was not helpful, said. I had to mail back product i have a hard time getting out. That's why I have home delivery and even though she sent a mailing label. I Don't have a way of getting to UPS store. I am not happy with this person. I have been a customer for over 20 years.

Rated 1 out of 5 stars
By Lin on Dec 3, 2025

We haven't noticed a difference

I purchased this at my vet's suggestion because my male cats who normally get along fine started attacking each other for no reason that we could see. So we decided

I purchased this at my vet's suggestion because my male cats who normally get along fine started attacking each other for no reason that we could see. So we decided to try it. They don't seem to mind the taste and I mix it in with some wet food every day. They have been eating it for about a month. Unfortunately it has done very little to stop their aggressive behaviour towards each other. :( I'm not sure if we need to keep giving it to them or how long it takes to start working or to make a difference. But the taste seems to be fine for them. It seems expensive to me, especially if it doesn't work.