Vectra 3D Flea & Tick Spot Treatment for Dogs, 21-55 lbs, 3 Doses (3-mos. supply)

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About This Item

Details

  • This monthly treatment helps protect dogs ages 8 weeks and older weighing 21–55 pounds from fleas, ticks, mosquitoes, lice, mites plus biting and sand flies—excluding mange mites.
  • Starts to reduce flea bites in five minutes and kill fleas in four hours.
  • Works to repel and kill fleas, ticks and mosquitoes–no biting required!
  • This easy-to-apply topical treatment is quick drying, fragrance free, non-greasy and waterproof after 24 hours.
  • No prescription required.

Ingredients

Instructions

FAQ

Learn More About Vectra From Our Team of Experts
Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

Frequently bought together

Questions & Answers

10 Customer Questions

Can you list the types of ticks this controls?

Some products that are safe for dogs are NOT safe for use around cats. I have 2 dogs and 1 cat is it safe to use on the dogs with a cat in the house?

Answer by Chewy • Jun 22, 2020
Due to their unique physiology and inability to metabolize the permethrin in Vectra 3D® for Dogs, this product must not be used on cats. As a precaution, when using this product in households with both dogs and cats, please keep the dog(s) that have been treated with a Vectra 3D® product separated from cats until the product has completely dried. Once dry, cats and dogs may again interact freely. Average drying time for Vectra 3D is 6-8 hours however drying times can vary. To ensure that the product is completely dry, you may run a facial tissue along the application site. When there is no evidence of moisture on the tissue, the product is dry.

Do I treat my dog with 3 doses right away, or use one dose a month?

Answer by Chewy • May 06, 2020
This flea and tick treatment should be administered once a month.

will flea medicine work on lice

Answer by Chewy • Feb 01, 2023
The triple-action formula of Vectra 3D kills lice on contact.
Reviews
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4.4
Rated 4.4 out of 5 stars
738 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

81% Positive

Effectiveness

82% Positive

Ingredients

82% Positive

Long-Term Benefits

80% Positive

260 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By kathleen on Jan 9, 2026

Awesome

With 3 dogs using this product, I haven't had a tick in the house since we started using this product a few years ago. I used to get ticks all the time, using brevecto,

With 3 dogs using this product, I haven't had a tick in the house since we started using this product a few years ago. I used to get ticks all the time, using brevecto, because it doesn't provide the 3 months coverage on all ticks. Now no tick bites on dogs or us!

Rated 3 out of 5 stars
By Lynette on Nov 25, 2025

Delivery Service is not good

I do not like using a delivery service that has an unmarked vehicle. I have canceled my subscription in Chewy because of it and will get my items elsewhere. As far

I do not like using a delivery service that has an unmarked vehicle. I have canceled my subscription in Chewy because of it and will get my items elsewhere. As far as the product itself I love it. It works. My dog is an outside dog and she does not get fleas and ticks.

Rated 2 out of 5 stars
By Kaytlin on Oct 23, 2025

Did not work

We have used this for both our dog and the cat version. In the last year my dog ended up with a blood borne tick disease and fleas, we kept using because we were

We have used this for both our dog and the cat version. In the last year my dog ended up with a blood borne tick disease and fleas, we kept using because we were told you have to use it for 3-6 months consistently so we kept going with it but cannot get rid of the fleas and now the cat has them too.We use every month but will no longer use this at all. It is also really oily and smells bad we tried to look past it but I do not recommend it at all.

Rated 1 out of 5 stars
By Melissa on Dec 21, 2025

Do not buy this poison

I used this on my dog and he began having seizures. He passed away 4 months later due to cluster seizures. DO NOT BUY THIS PRODUCT IT IS POISON.

I used this on my dog and he began having seizures. He passed away 4 months later due to cluster seizures. DO NOT BUY THIS PRODUCT IT IS POISON.

Rated 1 out of 5 stars
By FELICIA on Sep 6, 2025

WARNING : Very bad experience with

Vectra liquid it's taking long to dry- up to 6-8 hours. We put it in the evening and our dog started itching hour later. We used lower dose than indicated on the

Vectra liquid it's taking long to dry- up to 6-8 hours. We put it in the evening and our dog started itching hour later. We used lower dose than indicated on the pack since we were skeptical and our puppy is just 7.5 months old. He rolled on his back and was no way he will stay still without scratching. I was hopping is just temporary but in the next 48 hours his ears were red and itchy. We showered him and 4 days later he lost his appetite, got weak in legs and dizzy. This treatment is really dangerous at least for my GSP dog. I WOULD NEVER RECOMMEND IT. I better use a shampoo, wash him more often and treat the yard than use these Flea and Ticks treatments. It looks like we are poisoning our dogs. We had lost one of skin cancer and now we are worried our puppy may have long impact health issues because of this treatment. I regret I used it.

Rated 1 out of 5 stars
By Danielle on Sep 15, 2025

Mishandled Delivery

I found my package in a completely random place in my complex, no where near my door as I live on the second floor. Normally don’t have this issue, but this was

I found my package in a completely random place in my complex, no where near my door as I live on the second floor. Normally don’t have this issue, but this was a really awful delivery.

Rated 5 out of 5 stars
By Karen on Jul 26, 2025

Not to jinx myself but

I’ve been putting this on my dog for 9 years and she’s NEVER had a tick. What you need yo know is that we go to a highly wooded dog park every single day almost

I’ve been putting this on my dog for 9 years and she’s NEVER had a tick. What you need yo know is that we go to a highly wooded dog park every single day almost religiously. We walk in the woods about an hour and she runs all over in trees and plants/weeds of all types. If she ever did get a tick I don’t think she’d hold still for me to pull it off. She won’t hold still even for me to put the product on her back. She keeps spinning around trying to see what I’m doing. To get around this I put a dollop of peanut butter in her dish. While she licks on the peanut butter I easily apply the product. She’s weird. If she ever got a tick I don’t know how I’d get her to hold still for two seconds while I remove it.

Rated 3 out of 5 stars
By Dog Mom on Aug 10, 2025

Works to prevent fleas but dog had reaction

This product works well overall in preventing fleas. I did apply the product according to package directions. However, I noticed not long after application, my

This product works well overall in preventing fleas. I did apply the product according to package directions. However, I noticed not long after application, my dogs fur became discolored. Within hours, that discoloration spread outward from the spine area down his ribs. He scratched quit a bit and it would seem the product does not agree with him. It works to prevent fleas but it's not something we can use anymore as it has some side effects for our boy.

Rated 1 out of 5 stars
By Betsy on Jul 29, 2025

Won’t Use Again

We've been using Simparica Trio for tick/flee/heartworm treatment on our two doodles and very pleased with results. My vet suggested we add Vetra3D once a month

We've been using Simparica Trio for tick/flee/heartworm treatment on our two doodles and very pleased with results. My vet suggested we add Vetra3D once a month in addition to simparica because the ticks are so bad this year. My dogs have been visibly miserable ever since I applied it. Scratching 1’r biting at their backs and rolling around. I told the vet and was told to wash it off with Dawn dish washing detergent. I did not do that but it’s been five days and they are still so uncomfortable. I won’t use again.

Rated 5 out of 5 stars
By Debbie on Jul 21, 2025

My pups love this!

This is all I feed my two Chihuahua mix girls. One of them is a Chiweenie. The Chiweenie is getting older and has some toothissues and has an appointment soon to

This is all I feed my two Chihuahua mix girls. One of them is a Chiweenie. The Chiweenie is getting older and has some toothissues and has an appointment soon to have a dental exam cleaning and maybe pull a tooth. I bought her some wet dog food, thinking shewould like to eat that better. When I put the wet dog food down for her supper, she looked at me like I was crazy andwould not touch it. When I put this dry kibble in her bowl like I usually do, she devoured it. So if she needs something soft to eat, I’ll just wet this with water and let it get soft because it’s all she likes.