Zymox Enzymatic Dog & Cat Shampoo, slide 1 of 1

Zymox Enzymatic Dog & Cat Shampoo, 1-gal bottle

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Wash away your pet’s skin troubles with the Zymox Enzymatic Dog & Cat Shampoo. Using the healing power of enzymes, which are naturally occurring proteins, this shampoo is highly effective against bacterial, fungal and yeast infections, as well as itchy skin from allergies. It works by destroying the offending organisms and creating a protective barrier, using the increased potency of the proven antimicrobial LP3 Enzyme System plus vitamin D3 that also hydrates the skin. The enzymes have the added bonus of anti-inflammatory properties that calm and soothe the skin. And with only the mildest plants surfactants and no harsh ingredients, it’s gentle enough for even puppies and kittens, with a pleasing, mild fragrance.

Key Benefits
  • Highly effective against bacterial, fungal and yeast infections plus itchy skin from allergies while creating a protective barrier.
  • Proven antimicrobial LP3 Enzyme System inhibits, splits and destroys the offending organisms while leaving healthy cells alone.
  • The addition of vitamin D3 helps to relieve surface irritations and hydrate the skin.
  • Uses only the mildest plant surfactants with no harsh detergents, steroids or petroleum by-products. Pure and gentle enough for puppies and kittens with a pleasant, mild fragrance.
  • Made in the USA.

For external use only. Avoid contact with eyes. If condition worsens, consult your veterinarian. Store at room temperature. Keep out of reach of children.
If your furry friend is using a topical flea and tick treatment, please remember to follow the bathing instructions on the flea and tick packaging. Each treatment works differently and may require different wait times before water exposure.

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Purified Water, PEG-80 Sorbitan Laurate, Sodium Trideceth Sulfate, Cocamidopropyl Betaine, Disodium Lauroamphodiacetate, PEG-150 Distearate, Sodium Laureth-13 Carboxylate, Sodium Chloride, Quaternium-15, Tetrasodium EDTA, DMDM Hydantoin, Citric Acid, Cocamidopropyl Hydroxysultain, Cellulose Gum, Citrus Grandis (Grapefruit) Seed Extract, Flavor,Fragrance, Zinc Gluconate, Cholecalciferol (Vitamin D3), Lysozyme, Lactoferrin, Lactoperoxidase, Potassium Iodide.


Wet animal thoroughly with water. Apply Zymox Shampoo directly. Wash entire animal, concentrating on problem areas. Leave lather on for 3 to 5 minutes then rinse. Repeat if needed.

Powerful Antimicrobial and Antifungal Care

ZYMOX empowers pet parents with patented formulations of natural enzymes to help treat chronic infections in dogs, cats and horses. Their products are also formulated to be safe to use on kittens, puppies and even senior dogs. These solutions pack a potent antiseptic punch that targets the source of infections—bacteria, fungi and yeasts—to provide therapeutic relief, care, protection and prevention, without any antibiotics or harsh chemicals.

Powerful Antimicrobial and Antifungal Care

Committed to Healthy Ears, Skin and Coat, and Smiles

To ensure overall health from snout to tail on all four-legged pals, Zymox has developed products that are specially formulated for all the areas that commonly need infection relief, like the ears, teeth and gums, and skin and coat. To keep furry ones happy, their products treat ear infections, skin allergies, hot spots, bad breath, gum disease and more.

Ear Care Solutions

Ear Care Solutions: Effective, non-toxic solutions with special enzymes and mild cleansers to keep ears clean and fresh, and combat microbes that can cause ear infections.

Oral Care Solutions

Oral Care Solutions: Brushless solutions with unique enzymes to dissolve plaque and prevent its buildup, boost natural "good bacteria," and protect against gum disease to keep kitty and doggy smiles healthy.

Skin and Coat Health

Skin and Coat Health: Topical sprays and shampoos for dogs, cats and horses that form a powerful protective barrier against minor skin inflammations from bacteria and fungi, while cleaning and conditioning the coat—with some formulas utilizing hydrocortisone.

100% Safe, Gentle and Easy

Because Zymox formulas are made with 100% naturally derived enzymes from dairy, they are safe for anytime use, both for immediate soothing relief and to prevent infections. The powerful enzymes work to eliminate problem single-celled organisms such as bacteria, fungi and yeast, while leaving healthy cells untouched. This means no irritations for your pal!

Enzyme-Based and Antibiotic-Free

Enzyme-Based and Antibiotic-Free

Zymox products use a patented, gentle formulation that combines three potent, naturally occurring enzymes—lactoperoxidase, lysozyme and lactoferrin—that are sourced from milk products. These enzymes are proven to work together to eliminate the source of infection on your pet, without any toxins or antibiotics that can irritate or cause antibiotic resistance.


Zymox was founded in 1998 by Pamela Bosco, who sought to change the way that people treated and managed ear, oral and skin infections with a safer alternative to antibiotics. Enlisting the help of her brother—a scientist that developed the enzyme technology in Biotene—Bosco formulated a powerful enzyme-based solution to help treat infections in dogs, cats and horses with no toxins, chemicals or antibiotics. Committed to keeping all four-legged pals healthy, they offer USA-made and sourced products to treat, soothe and protect against bacterial and fungal infections gently and 100% naturally.


Rating: 4.0 of 5 stars 11 Reviews 11 Reviews 4 out of 5 Stars

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11 Reviews

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  • 4 out of 5 stars

    Shampoo pump

    By Bear on Nov 21, 2021

    Love the shampoo..however the pump doesn't work. Very disappointing.

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  • 1 out of 5 stars

    Get product Faulty pump tragedy!

    By Stormie on Mar 31, 2021

    110 service dog very scared of the bath time! This product has the stuff to care for my baby skin is very sensitive he's a 'blue nose- I'm disabled in a wheelchair and unfortunately the pump was faulty and this turn into a tragedy in my kitchen floor very expensive product I just got all spilled and it was a terrible bath time unfortunately. Never even open the conditioner it was an absolute tragedy no man:-(

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  • 5 out of 5 stars

    Nice smell

    By Vatosmom on May 20, 2021

    My GSD has a very bad yeast problem. The protocol that he's on requires weekly baths with a fungicidal shampoo. I'm hoping the Zymox works. I was pleased with the ear drops.

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  • 5 out of 5 stars

    Awesome for skin

    By Sashasmom on May 27, 2021

    This is an awesome shampoo if you need to bath your dog frequently. It doesn't damage the skin or fur, and after your dog doesn't smell like a wet dog.

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  • 1 out of 5 stars

    no pump included with product

    By Chris on Sep 7, 2020

    No pump was included with product. Great shampoo, difficult to use without pump

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  • 4 out of 5 stars

    Very good shampoo

    By MissV100 on Oct 18, 2019

    Our black lab/ border collie dog is 6 years old now and having skin allergies like crazy this year. So far this shampoo is helping some. Less scratching and less flaky skin. Her sores seem to be healing. We’ve given her 3 baths in 2 weeks. Hopefully we can back down to once every 7 to 10 days. Right now, she still gets stinky after a few days.

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  • 5 out of 5 stars

    This shampoo is amazing.

    By ChasesMom on Apr 14, 2019

    My dog is an 11 years old boxer shepherd mix. He has medium long hair and has developed allergies to almost every protein in addition to many enviromental allergies. Prior to finding this shampoo, he was always scratching, licking, biting and chewing at himself. His coat was dull and coarse and he stunk. Even bathing him with other shampoos left him smelling like wet dog after a day or two. With this product, it has not only helped tremendously with the scatching, biting, licking and chewing but his coat is shiny, soft and he smells clean for weeks.

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  • 5 out of 5 stars

    Dog shampoo

    By Jbran on May 18, 2019

    Best shampoo and conditioner smells so good. My bichon poo who always has tangled hair I now can easily comb through it!! I Love it.

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  • 5 out of 5 stars

    Love This Product

    By Jedomaster on May 9, 2019

    I love this shampoo for my pups. It's so concentrated, a little goes a long way. The result is clean, sweet smelling pups.

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  • 4 out of 5 stars

    Great product and wouldn't be without it.

    By Franny on Jan 31, 2019

    I've been using Zymox for years. I purchased a gallon bottle this time and it's a real struggle to pump out the shampoo due to the product's thickness. The pumping dispenser on the gallon Zymox needs to be redesigned.

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