Advantage Multi Topical Solution for Dogs, 88.1-110 lbs, (Brown Box), 6 Doses (6-mos. supply)
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Most prescriptions are delivered within 3-5 days.About This Item
Details
- Advantage Multi provides 6-in-1 protection from fleas, heartworms, roundworms, hookworms, whipworms, and sarcoptic mange.
- One monthly dose kills worms all month long.
- Kills fleas through contact; pests don�t have to bite your dog to die
- Treats & controls roundworms, hookworms & whipworms
- Easy-to-apply topical treatment, no hard-to-swallow pills. Perfect for patients that struggle with oral medications.
Ingredients
Active ingredients: 500 mg Imidacloprid (10%), 125mg Moxidectin (2.5%)
Instructions
The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration.
Store at room temperature between 39° - 77°F.
FAQ
Advantage Multi for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.
Do not apply to irritated skin.
Contact with eyes can lead to eye irritation and corneal ulceration. If contact with eyes occurs, hold the dog's eyelids open, flush thoroughly with water, and contact your veterinarian.
- Remove one dose applicator tube from the package.
- While holding the tube in an upright position, remove the cap from the tube.
- Turn the cap over and push the other end of the cap onto the tip of the tube.
- Twist the cap to break the seal and then remove cap from the tube.
- The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible.
For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog. Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.
Advantage Multi for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.
Advantage Multi for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi for Dogs should not be used past its expiration date.
We recommend bathing before applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.
Yes. A study showed that when dogs went swimming 60 minutes after application, Advantage Multi for Dogs still effectively prevented heartworm disease. A study also showed that swimming 4 days after treatment did not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations.
You should apply Advantage Multi for Dogs monthly (every 30 days), all year-round.
Advantage Multi for Dogs is applied to the pet's skin. The active ingredient spreads over your dog's body to kill fleas through contact so they don't have to bite your dog to die.
Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi for Dogs is heartworm prevention that forgives if you forget. It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month. After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.
No. Advantage Multi for Dogs provides broad-spectrum protection against heartworms, fleas, roundworms, hookworms, whipworms and the skin parasite sarcoptic mange. If you are concerned about ticks, Bayer has effective products that treat and prevent tick infestations.
Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.

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Customers Mention
Ease of Use
Effectiveness
Ingredients
Long-Term Benefits
65 Customer Reviews
No itching or irritation
She has tried one application so far. There was no redness or irritation on her skin. The reviews from other people seam good for keeping fleas off and preventing
She has tried one application so far. There was no redness or irritation on her skin. The reviews from other people seam good for keeping fleas off and preventing disease. I like its ease of use and one application controls fleas and heartworm.
Always good service
As always, my order was handled excellently... They contacted my vet, filled the order and sent it in a timely manner
As always, my order was handled excellently... They contacted my vet, filled the order and sent it in a timely manner
Always works
where he still catches with other products
where he still catches with other products
Topical flea
My pup has seizures so can’t use conventional flea meds. last yr she suffered w/ horrible fleas , this year we are good Very grateful for this option for her
My pup has seizures so can’t use conventional flea meds. last yr she suffered w/ horrible fleas , this year we are good Very grateful for this option for her
Service and Good Product
Advantage Multi has helped control our dog’s hookworms. I asked the Chewy pharmacist (whose name I wish I could remember) if the prescription could be mailed a
Advantage Multi has helped control our dog’s hookworms. I asked the Chewy pharmacist (whose name I wish I could remember) if the prescription could be mailed a few days earlier than it was originally scheduled, and he cheerfully agreed AND it arrived just as I had requested. I wish every company provided such excellent customer service!
Easy to use.
Only negative is this is a topical and I can smell the chemical on he’s breath for about 3 days after application. Definitely it works really well, no fleas, or
Only negative is this is a topical and I can smell the chemical on he’s breath for about 3 days after application. Definitely it works really well, no fleas, or heartworms. He has used it for years with no negative effects, But the smell on his breath didn’t seem healthy to me!
Grade of incomplete
Can't say much yet. We are using the Advantage Multi in combination with Drontel to treat for hookworms. After six doses of both, the resistant hookworms are still
Can't say much yet. We are using the Advantage Multi in combination with Drontel to treat for hookworms. After six doses of both, the resistant hookworms are still there. We're going with another six rounds of both.
Chewy makes it so easy for me.
Advantage tropical solution is so easy to give heartwormer to my dogs.
Advantage tropical solution is so easy to give heartwormer to my dogs.
If I do find a tick on my dog it’s dead
My dog is fairly co-operative when I’m applying it. It’s effective. Don’t like the temporary discoloration of his hair where applied.
My dog is fairly co-operative when I’m applying it. It’s effective. Don’t like the temporary discoloration of his hair where applied.
Cured hookworms!
No other meds had the moxidectin that was needed to kill hookworms. After 4-months of treatment with other drugs, this was the only thing that worked.
No other meds had the moxidectin that was needed to kill hookworms. After 4-months of treatment with other drugs, this was the only thing that worked.





