Advantage Multi Topical Solution for Dogs, 88.1-110 lbs, (Brown Box)
By Advantage Multi

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About This Item
Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Advantage Multi for Dogs is a broad-spectrum topical solution prescribed by veterinarians to provide a convenient monthly application to help alleviate canine companions from symptoms caused by pesky parasites. This easy-to-use topical solution helps to treat circulating microfilariae in heartworm-positive canines, fights against adult fleas, treats and controls flea infestations, and sarcoptic mange, along with common intestinal parasites including roundworms, hookworms and whipworms—this medication may also prevent heartworm disease in some dogs.
Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.
Specifications
Item Number | 146322 |
---|---|
Common Brand Name(s) | Advantage Multi |
Generic Name | Imidacloprid, Moxidectin |
For Use With | Dogs |
Administration Form | Topical |
Dosage Measure | n-a |
Breed Size | Large Breeds |
Product Form | Solution |
Strength | 500 mg Imidacloprid and 125 mg Moxidectin |
Health Condition | Heartworms, Fleas, Roundworms, Hookworms, Mange, Whipworms |
Drug Type | Parasiticide |
Uses
Advantage Multi for Dogs is indicated for the prevention of heartworm disease caused by Dirofilaria Immitis and the treatment of Dirofilaria Immitis circulating microfilariae in heartworm-positive dogs. Advantage Multi for Dogs kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis). Advantage Multi for Dogs is indicated for the treatment and control of sarcoptic mange caused by Sarcoptes Scabiei Varcanis.
Possible Side Effects
Contact your veterinarian if your dog experiences localized pruritus, hematochezia, diarrhea, vomiting, lethargy, inappetence or pyoderma.
Drug & Food Interactions
In a well-controlled field study Advantage Multi for Dogs was used safely in dogs concomitantly receiving ACE inhibitors, anticonvulsants, antihistamines, antimicrobials, chondropprotectants, corticosteroids, immunotherapeutics, MAO inhibitors, NSAIDs, ophthalmic medications, sympathomimetics, synthetic estrogens, thyroid hormones, and urinary acidifiers.
Precautions
Do not dispense dose applicator tubes without complete safety and administration information. Use with caution in sick, debilitated, or underweight animals. The safety of Advantage Multi for Dogs has not been established in breeding, pregnant, or lactating dogs. The safe use of Advantage Multi for Dogs has not been established in puppies and dogs less than 7 weeks of age or less than 3 lbs. body weight. Prior to administration of Advantage Multi for Dogs, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. The safety of Advantage Multi for Dogs has not been evaluated when administered on the same day as an adulticide. Advantage Multi for Dogs is not effective against adult D. Immitis.
Ingredients
Active ingredients: 500 mg Imidacloprid (10%), 125mg Moxidectin (2.5%)
Recommended Dosage
The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration.
Storage Instructions
Store at room temperature between 39° - 77°F.
Is Advantage Multi for Dogs waterproof?
Advantage Multi for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application.
How do I apply Advantage Multi for Dogs?
Do not apply to irritated skin.
- Remove one dose applicator tube from the package.
- While holding the tube in an upright position, remove the cap from the tube.
- Turn the cap over and push the other end of the cap onto the tip of the tube.
- Twist the cap to break the seal and then remove cap from the tube.
- The dog should be standing for application. Part the hair on the back of the dog between the shoulder blades until the skin is visible.
For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Do not apply an amount of solution at any one location that could run off the side of the dog. Do not let this product get in your dog's mouth or eyes. Do not allow the dog to lick any of the application sites for 30 minutes.
How old does my dog have to be to use Advantage Multi for Dogs?
Advantage Multi for Dogs is for use on puppies at least 7 weeks old and weighing at least 3 pounds.
Does Advantage Multi for Dogs expire?
Advantage Multi for Dogs does have an expiration date that can be found on the bottom edge of the package. Advantage Multi for Dogs should not be used past its expiration date.
When can I bathe my dog after using Advantage Multi for Dogs?
We recommend bathing before applying product. The product can be applied once the pet is towel dried. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease. Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Please use a pet shampoo that is soap-free.
Can my dog go swimming after using Advantage Multi for Dogs?
Yes. A study showed that when dogs went swimming 60 minutes after application, Advantage Multi for Dogs still effectively prevented heartworm disease. A study also showed that swimming 4 days after treatment did not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations.
When should I put Advantage Multi on my dog?
You should apply Advantage Multi for Dogs monthly (every 30 days), all year-round.
How does Advantage Multi for Dogs work to kill fleas?
Advantage Multi for Dogs is applied to the pet's skin. The active ingredient spreads over your dog's body to kill fleas through contact so they don't have to bite your dog to die.
What if I miss an Advantage Multi for Dogs heartworm treatment?
Life happens. If you forget or miss a dose, simply treat your dog immediately. Advantage Multi for Dogs is heartworm prevention that forgives if you forget. It kills immature heartworms that may already be in your dog and continues to prevent future infection by killing newly acquired baby worms throughout the month. After a single dose, if you forget and go more than 30 days in between treatments, just treat immediately and resume your monthly schedule.
Does Advantage Multi for Dogs kill ticks?
No. Advantage Multi for Dogs provides broad-spectrum protection against heartworms, fleas, roundworms, hookworms, whipworms and the skin parasite sarcoptic mange. If you are concerned about ticks, Bayer has effective products that treat and prevent tick infestations.
How often can I use Advantage Multi for Dogs?
Use monthly, year-round, to prevent heartworm disease; kill adult fleas; treat flea infestations; treat and control hookworms, roundworms and whipworms; and treat and control sarcoptic mange.

Dosage Chart
Color on Box | Weight Range | Volume | Strength | Dosage | Product Page |
---|---|---|---|---|---|
Green | 3-9 lbs | 0.4 mL | 40 mg Imidacloprid & 10 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Teal | 9.1-20 lbs | 1.0 mL | 100 mg Imidacloprid & 25 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Red | 20.1-55 lbs | 2.5 mL | 250 mg Imidacloprid & 62.5 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Blue | 55.1-88 lbs | 4.0 mL | 400 mg Imidacloprid & 100 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
Brown | 88.1-110 lbs | 5.0 mL | 500 mg Imidacloprid & 125 mg Moxidectin | Apply each dose once a month | ✓-Click Here |
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ReviewsWrite a Review
15 Customer Reviews
A lot of liquid
I have used Advantage Multi on my dogs for years and think it is a great product. My dogs usually weigh less than 88 lbs and the product amount is similar to a teaspoon...once the dog goes over 88 lbs the amount of liquid seemingly triples. A whole lot of stuff to apply to a dog.
Bella Likes It
I have tried everyway to get my dog to take a pill. It isn't going to happen. This is easy to apply and works well.
No Brainer
It's a "No Brainer" why I only shop Chewy for my pet care products. I'm serious, Chewy sells the BEST products available, such as Advantage Multi, and at easy to digest prices. I don't research products any more, I go with what Chewy has on their shelves, and have been for a long time. That's the truth. A 78 year old Pet owner.
Excellent Product
Advantage Multi is the product I have used on my dogs for many years. This was purchased for my still growing puppy. This will keep her healthy and me, very happy.
Ssslllooooowwwwww delivery
The product is fine, but delivery was very slow. When you're needing a product to treat heartworm eggs, waiting 2 weeks is an eternity.
problemssss
I wish my account wouldn't be charged until the whole order is ready to ship.
Keeps bugs, etc, at bay
We’ve used other heart worm, flea and tick medicines, but this is the only one that keeps our dog from getting worms, too. We ran out, last fall, and gave him Heartguard, and Nexguard, which work great against heart worm, fleas and ticks, but our dog got Hookworms again. Worm RXs don’t work on him. This does, and it’s all-in-one for the other problems.
excellant for dogs
I"ve been using this on my dog for several years , I highly recommend it She does not have fleas or ticks while using this
Best thing for Woody
Woody, our lab has the best all around protection for the outdoors. It safe guards him from everything out there (fleas, ticks, etc.) as well as heartworm. We want only the best for our dog!
Does the job
This product works great for our 144lb great dane. We have been using this product in the smaller weight for our miniature dachshund. We have always been satisfied.