Advantage Multi Topical Solution for Dogs, 55.1-88 lbs, (Blue Box), 6 Doses (6-mos. supply)

Have a Chewy account?
Sign in to quickly add pet health details.
$121.19 First Time Autoship Price
this order
Save 35% (up to $20) today when you set up Autoship. 

$134.13 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Never miss a dose with easy refills
  • Skip, change, or cancel anytime
$141.19 Chewy Price
($23.54 /ea)
Promo, Save 20% on first Rx order with code RX20
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

In Stock
FREE delivery
Usually arrives in 3-5 days
Prescription approval made easy
We’ll reach out to your vet clinic.

No interest if paid in full in 6 months on PayPal purchases of $149+. .

Medications ship separately. Delivery times may vary.

About This Item

Details

  • Advantage Multi provides 6-in-1 protection from fleas, heartworms, roundworms, hookworms, whipworms, and sarcoptic mange.
  • One monthly dose kills worms all month long.
  • Kills fleas through contact; pests don�t have to bite your dog to die
  • Treats & controls roundworms, hookworms & whipworms
  • Easy-to-apply topical treatment, no hard-to-swallow pills. Perfect for patients that struggle with oral medications.

Ingredients

Instructions

FAQ

Learn More About Advantage Multi From Our Team of Experts
4.8
Rated 4.8 out of 5 stars
695 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

91% Positive

Effectiveness

91% Positive

Ingredients

91% Positive

Long-Term Benefits

92% Positive

273 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Steven on Dec 13, 2025

Got a decent deal on my meds

I got the meds in a timely manner. I got a good deal on the meds compared to my vet's price. I always suggest that people look for the best price for meds to keep

I got the meds in a timely manner. I got a good deal on the meds compared to my vet's price. I always suggest that people look for the best price for meds to keep overall pet healthcare costs down. Private equity is buying most vets, so know your vet and be aware where you can get good quality care before you need to use it.


Rated 1 out of 5 stars
By Greg on Dec 20, 2025

Stop sending surveys

Please stop sending surveys. You sold me a product. great. I don't want to be pestered with what? 6 or so requests for surveys? Just make sure you deliver the product

Please stop sending surveys. You sold me a product. great. I don't want to be pestered with what? 6 or so requests for surveys? Just make sure you deliver the product requested.


Rated 1 out of 5 stars
By Victor on Sep 19, 2025

Does not kill fleas

Have been using on my dogs. They are house dogs and also highly allergic to fleas. My floors are wooden and vacuumed daily. I washed their beds which I do weekly

Have been using on my dogs. They are house dogs and also highly allergic to fleas. My floors are wooden and vacuumed daily. I washed their beds which I do weekly. They are constantly itching and I assumed it was something else but when I rolled them over and look closely they have fleas. Three days after treatment I still find a flea on them and the itching has not stopped. I have had to use other methods to control fleas. It just doesn't kill them and they smell like chemical. This is a dangerous product to begin with and it's not like I can just retreat them or be able to use another product within the 30 days. It makes me wonder if it's really taken care of the worms and hearworm prevention. For the price of the product I would think it should work better than it does.


Rated 5 out of 5 stars
By dawnshort.muller on Oct 29, 2025

Awesome Customer Service

Needed to return topical treatment -Veterinarian changed medication before meds arrived so we would never need or use it. Unopened & unused, Chewy offered quick

Needed to return topical treatment -Veterinarian changed medication before meds arrived so we would never need or use it. Unopened & unused, Chewy offered quick refund for its return. Great service!


Rated 5 out of 5 stars
By Margaret on Dec 5, 2025

My dog hates those big chewables, so topical is the way to go!

Flea & intestinal parasite + heartworm protection all in a small dispenser that holds a surprising amount of fluid.

Flea & intestinal parasite + heartworm protection all in a small dispenser that holds a surprising amount of fluid.


Rated 5 out of 5 stars
By Lari on Aug 8, 2025

Fast shipping great for food allergies

Arrived super quick. I was able to place the order through Chewy Vet Care Cinco Ranch while Taters was in for a recheck. I love that now that he has a food allergy

Arrived super quick. I was able to place the order through Chewy Vet Care Cinco Ranch while Taters was in for a recheck. I love that now that he has a food allergy I have an effective, easy to use heartworm and flea prevention for him that’s topical. He hates pills and would only eat the one that he was allergic too so this is much easier!


Rated 5 out of 5 stars
By Jeri on Oct 2, 2025

Vet recommended for our shelter dog that previously had Heartworm.

She is predominantly an indoor dog but we’ve been happy overall with this product. Make sure to apply it per instructions to minimize product on your dog’s fur

She is predominantly an indoor dog but we’ve been happy overall with this product. Make sure to apply it per instructions to minimize product on your dog’s fur.


Rated 5 out of 5 stars
By Eleanor on Nov 4, 2025

My Grace has done very well on this prescription for 8 years or more. ription.

As stated, Grace has remained free of all conditions that Advantage Multi prevents.

As stated, Grace has remained free of all conditions that Advantage Multi prevents.


Rated 5 out of 5 stars
By Mary on Oct 17, 2025

Received what I ordered.

Received what I ordered. At the best price I could find using a Cash earned and Prescription code.

Received what I ordered. At the best price I could find using a Cash earned and Prescription code.


Rated 5 out of 5 stars
By Tamara on Oct 13, 2025

Takes care of heartworm

I’ve been using it for years. I didn’t know it handles heart worm eliminating the need for heart guard.

I’ve been using it for years. I didn’t know it handles heart worm eliminating the need for heart guard.