Clomipramine Hydrochloride (Generic) Tablets, 40 mg, 60 tablets

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$70.00 First Time Autoship Price
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$90.00 Chewy Price
($1.50 /ea)
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Medications ship separately. Delivery times may vary.

About This Item

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Some furry friends have a very hard time being separated from their pet parents, but thankfully there are ways to help. Clomipramine Hydrochloride (Generic) Tablets is a prescriptions medication formulated to help reduce clinical signs of separation anxiety. It works by affecting serotonergic and noradrenergic neuronal transmission into your pets central nervous system. And for easy oral administration, this medication comes in a convenient uncoated tablet form.

We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.

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4.5
Rated 4.5 out of 5 stars
333 Ratings
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Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

87% Positive

Effectiveness

85% Positive

Ingredients

83% Positive

Long-Term Benefits

84% Positive

113 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Helen on Dec 2, 2025

So painless!

I have been ordering my dog's medication from a Chewy competitor. I decided to give Chewy a try because the other company kept running out of the medication, taking

I have been ordering my dog's medication from a Chewy competitor. I decided to give Chewy a try because the other company kept running out of the medication, taking forever to get approvals, and dealing with the company was a nightmare! Imagine my shock when part of my autoship was delivered within days. And within a couple more days, Chewy had the prescription from Buddy's vet and his meds were on the way. I am now an official Chewy fan. BRAVO!!

Rated 1 out of 5 stars
By Dominique on Dec 2, 2025

Had no impact on my dog

While this may work fine for others, I noticed no impact at all with my Boston terrier/ French bulldog mix. I was hoping it would help offset her crippling separation

While this may work fine for others, I noticed no impact at all with my Boston terrier/ French bulldog mix. I was hoping it would help offset her crippling separation anxiety but after a couple of months on this med, we noticed to impact with that whatsoever. She’s fine otherwise so we stuck with giving her Trazadone before leaving her alone. Even that was hit or miss, depending on the timing of when it was given.

Rated 1 out of 5 stars
By Sherida on Jan 2, 2026

Only half the prescription quantity arrived

My pharmacy order arrived, but although the label states a quantity of 60, there was only an unopened bottle of 30 tucked inside a pharmacy bottle - only a 15 day

My pharmacy order arrived, but although the label states a quantity of 60, there was only an unopened bottle of 30 tucked inside a pharmacy bottle - only a 15 day supply. I was charged for 60. Is the remainder on the way?

Rated 5 out of 5 stars
By Caroline on Jan 17, 2026

Quality

This medicine helps Tyson and Rosie out so much. Without this, they both struggle.

This medicine helps Tyson and Rosie out so much. Without this, they both struggle.

Rated 1 out of 5 stars
By K. on Sep 10, 2025

BEWARE! CAN CAUSE PERMANENT MEMORY DAMAGE!!!!

As a human. I was prescribed this. Within 2 weeks I lost roughly 90-95% of my short term memory. I went off it immediately. Its been a year since discontinuing

As a human. I was prescribed this. Within 2 weeks I lost roughly 90-95% of my short term memory. I went off it immediately. Its been a year since discontinuing and I have permanent memory damage. Im speaking for the fur babies that cant...please watch for any changes in behavior. I highly HIGHLY recommend not using this medication. Its effects and be permanent and life altering.

Rated 5 out of 5 stars
By Lisa on Jan 12, 2026

Instant support

This helped my dog to settle quicker and be less anxious in just days.

This helped my dog to settle quicker and be less anxious in just days.

Rated 3 out of 5 stars
By Linda on Oct 16, 2025

The Jury Is Still Out

I’m not sure this meditation is helping our pup with her anxiety. She’s been on it for a couple of months and the vet says to give it more time. Time will tell,

I’m not sure this meditation is helping our pup with her anxiety. She’s been on it for a couple of months and the vet says to give it more time. Time will tell, I guess.

Rated 4 out of 5 stars
By Lee on Oct 23, 2025

Helped behaviors

Overall has worked. My cat has been on this for a year now and she only sprays or marks very rarely. Has chilled out a lot

Overall has worked. My cat has been on this for a year now and she only sprays or marks very rarely. Has chilled out a lot

Rated 5 out of 5 stars
By Tami on Oct 2, 2025

Great

This medication works for my cat. She is happier and healthier with medication. Keeps her from hiding and she is using the litter box consistently.

This medication works for my cat. She is happier and healthier with medication. Keeps her from hiding and she is using the litter box consistently.

Rated 5 out of 5 stars
By Louisa on Jan 17, 2026

Works quickly

Helps tremendously with anxiety and bad behavior!

Helps tremendously with anxiety and bad behavior!