Credelio Quattro Chewable Tablets for Dogs, 6.1-12 lbs, 6 Chewables (6-mos. supply)

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About This Item

Details

  • Credelio Quattro: The broadest1 parasite protection of its kind covering 6 types of parasites, including ticks, in one chewable tablet.
1

Based on label comparison of the number of parasite types covered in an isoxazoline endectocide. - This monthly flea and tick treatment also protects against heartworm disease and three intestinal worms that can be passed to humans – roundworms, hookworms† and tapeworms † Uncinaria stenocephala - Easy-to-Give Chewable: This FDA-approved parasite protection comes in a flavored chewable tablet that is given once a month with food or within 30 minutes of a meal. - Prescription Only: Credelio Quattro is a prescription medication for puppies and dogs at least 8 weeks old and weighing at least 3.3 lbs.

Ingredients

Instructions

FAQ

Get 6-in-1 Parasite Protection

Introducing Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) for dogs, a prescription medication that protects your dog from common parasites. Unlike other chewables, Credellio Quattro protects against 6 types of parasites, including ticks, fleas, heartworm disease and three intestinal worms that can be passed to humans – 3 species of tapeworms, roundworms and hookworms.

Protection in a Tasty Chewable

Credelio Quattro combines convenience with flavor. A beef-flavored, once-monthly tablet that makes it easy to administer. Enjoy peace of mind knowing your dog’s protection is effective and easy to give.

The Power of Four

Credelio Quattro features four tried and true active ingredients designed to combat parasites effectively. With lotilaner, moxidectin, pyrantel and praziquantel, this advanced formula provides your pet with the broadest parasite protection of its kind based on label comparison of the number of parasite types covered.

Shown To Be Safe for Dogs and Puppies

Use Credelio Quattro to help protect your dog proactively before problems happen. This preventive treatment is shown to be safe for puppies as young as 8 weeks old and weighing at least 3.3 lbs.

About Credelio Quattro

Prescription only. Ask your veterinarian if Credelio Quattro is right for your dog.

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Indications

Credelio Quattro is indicated for the prevention of heartworm disease and the treatment and control of roundworm, hookworm, and tapeworm infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations for 1 month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater.

Important Safety Information

Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis. The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. For complete safety information, please see the Credelio Quattro product label or ask your veterinarian.

4.6
Rated 4.6 out of 5 stars
118 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

85% Positive

Effectiveness

84% Positive

Ingredients

79% Positive

Long-Term Benefits

92% Positive

37 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
By Andrea on Oct 13, 2025

Credelio Quattro Doesn’t Work!

Two weeks ago I gave my Dachy his first pill of Credelio Quattro. I was familiar with combining the plain Credelio one week to be followed the next week with the

Two weeks ago I gave my Dachy his first pill of Credelio Quattro. I was familiar with combining the plain Credelio one week to be followed the next week with the Interceptor. It worked well - no ticks, no fleas -but he hated the taste of the Interceptor. To make a long story short, last night I removed 8 live ticks from around his face! Three were embedded and bled once they were pulled out! It bothers me that I paid close to $200 for something that doesn’t work!


Rated 2 out of 5 stars
By Lorena on Jan 17, 2026

OK

It did not set well with my little dog.Too strong perhaps. She was lethargic and something was off after dose. Not renewing.

It did not set well with my little dog.Too strong perhaps. She was lethargic and something was off after dose. Not renewing.


Rated 5 out of 5 stars
By Becky C on Sep 14, 2025

Thankful for This Combined Pill

We have a 10 pd shih tzu who can lock her jaw and there is no getting a pill down her and she is too distrusting for cheese and pill pockets. We were doing the 6

We have a 10 pd shih tzu who can lock her jaw and there is no getting a pill down her and she is too distrusting for cheese and pill pockets. We were doing the 6 month shot for heartworms and discovered we could disguise the flea/tick pill in liverwurst. Now we no longer have to do the shot and this combo pill seems to be just as effective on fleas and ticks (something we see here in the Smokies).


Rated 5 out of 5 stars
By Shannon on Dec 8, 2025

Outstanding service

It is a great deal. Chewy kept me informed while they communicated with the vet. This made it so easy for me.

It is a great deal. Chewy kept me informed while they communicated with the vet. This made it so easy for me.


Rated 5 out of 5 stars
By Donna on Oct 1, 2025

2 in 1

Love that it has the heartworm and flea & tick in one tablet. Nuzzle decided he didn't like the flea & tick tablet anymore. Hopefully he likes this new tablet

Love that it has the heartworm and flea & tick in one tablet. Nuzzle decided he didn't like the flea & tick tablet anymore. Hopefully he likes this new tablet.


Rated 5 out of 5 stars
By Eriko on Nov 14, 2025

Good job

As usual, ordering, sending request to the vet, and delivery was very quick and smooth. Thank you!

As usual, ordering, sending request to the vet, and delivery was very quick and smooth. Thank you!


Rated 5 out of 5 stars
By Lorien on Nov 10, 2025

All in one treatment

Easy to administer, no bad reaction, no skin irritation which my dog had after a topical flea med.

Easy to administer, no bad reaction, no skin irritation which my dog had after a topical flea med.


Rated 1 out of 5 stars
By Kenneth on Nov 6, 2025

Unlikeable

Purchased to help clear up reverse sneeze condition. My dog didn't like the smell or taste.

Purchased to help clear up reverse sneeze condition. My dog didn't like the smell or taste.


Rated 4 out of 5 stars
By Beverly on Dec 14, 2025

Credit Quattro

She still scratches sometimes, but it seems pretty good

She still scratches sometimes, but it seems pretty good


Rated 5 out of 5 stars
By Marilyn on Dec 31, 2025

Kills many different intestinal parasites

Kills roundworm, tapeworm, hookworm, and others

Kills roundworm, tapeworm, hookworm, and others