Doxycycline Hyclate (Generic) Capsules, slide 1 of 1

Doxycycline Hyclate (Generic) Capsules

Prescription Item

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In stock
Strength: 100-mg
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Count: 1 capsule
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Doxycycline Hyclate is an antibiotic prescribed to treat a variety of infections including Lyme disease, rocky mountain spotted fever, chlamydia and bacterial infections. It might also help with urinary tract, respiratory tract and wound infections. This medication comes in an oral capsule form. Customers may receive this drug under the name Doxirobe.

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Doxycycline is a broad-spectrum antibiotic used to treat many diseases carried by ticks. Doxycycline is used to treat infections such as ehrlichiosis, Lyme Disease, Rocky Mountain spotted fever, salmon poisoning, toxoplasmosis, and leptospirosis.

Possible Side Effects

The most commonly reported symptoms have included nausea and diarrhea, which are minor. Some pets may also suffer from loss of appetite, hair loss, lesions, mental confusion, and jaundice. If you observe more severe reactions like facial hives, swelling of the lips or tongue and difficulty breathing, immediately discontinue use and contact your veterinarian, as these may be signs of an allergic reaction.

Drug & Food Interactions

Talk to your veterinarian about any other drugs the pet is taking before starting this medication.


Do not give Doxycycline to pregnant or nursing pets. Do not give multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after giving this medication, as these products can reduce the effectiveness of Doxycycline. Doxycycline may make a pet's skin more sensitive to sunlight and sunburn may occur. Throw away any unused medication when it expires or when it is no longer needed. Expired Doxycycline can cause a dangerous syndrome that can result in damage to the kidneys. 

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Please note product may arrive in a Chewy Pharmacy vial.

Also available in tablets.

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  1. Prescribing Information

See all items by Doxycycline

  • Item Number
  • Common Brand Name(s)
    Doxirobe, Vibramycin, Doryx
  • For Use With
    Dogs & Cats
  • Generic Name
    Doxycycline Hyclate
  • Administration Form
  • Product Form
  • Health Condition
    Wounds, Urinary Tract Infections (UTI), Respiratory Infections, Skin Infections, Lyme Disease, Leptospirosis, Rocky Mountain Spotted Fever, Ehrlichiosis
  • Drug Type


Recommended Dosage

Always follow the dosage instructions provided by your veterinarian.

Storage Instructions

Unless otherwise stated by the manufacturer, store in a tightly closed container at room temperature 60° - 86°F, protected from light, heat, and moisture. Keep out of reach of children and pets.


What is Doxycycline?

Doxycycline is an antibiotic used to treat infections like Lyme disease, chlamydia, Rocky Mountain spotted fever, and bacterial infections caused by susceptible organisms.

What are the benefits of Doxycycline?

  • Treats a broad spectrum of infections
  • Effective against tick-borne diseases like Lyme disease and Chlamydia
  • Used for treatment of urinary tract, respiratory tract and wound infections

How is this medication given?

Use as directed by your veterinarian.

How does this medication work?

Doxycycline is a tetracycline antibiotic that treats bacterial infections. It works by interrupting the production of proteins by bacteria. It's effective against a wide variety of bacteria.

Rating: 3.4 of 5 stars 5 Reviews 5 Reviews 3.4 out of 5 Stars

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Rating: 3.4 of 5 stars 3.4 / 5

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5 Reviews

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  • 3 out of 5 stars

    Not what I was looking for

    By RB11 on Apr 7, 2021

    If they were pills rather than capsules they would be better for small dogs

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  • 5 out of 5 stars

    Lifetime medication

    By jules on Sep 21, 2020

    My dog has SLO(systemic lupiod onchodystrophy). This medication is keeping her in remission. I was getting it at a local pharmacy for $36 a month until Goodrx stopped covering pet meds. Without the prescription plan it was over $200! I am glad someone mentioned to try Chewy. I can continue her medications and not worry about how I will pay for them. The capsuls are easy to pop open and mix into her food. No hassle of trying to get her to take them!

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  • 3 out of 5 stars

    A necessary purchase.

    By Rick on Jul 22, 2020

    This was a necessary purchase in order to treat lyme disease in my fur buddy. The purchase was easy, and the price was exceptional. The drug seems to be killing the bacteria associated with Lyme Disease. Thank you Chewy!

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  • 3 out of 5 stars

    Hard to administer

    By Jayce on Oct 2, 2019

    I'm a pro at administering pills to dogs and these tabs are difficult to administer. They are small and stick to my hands, especially if they get wet. I'm considering switching to the capsules.

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  • 3 out of 5 stars


    By Kitster on Feb 23, 2019

    Our dog was accustomed to the tablets and these capsules are a little tricky to administer as I had been hiding it in peanut butter

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