Equioxx (Firocoxib) Tablets for Horses, 57 mg, 1 Tablet

Prescription Item

  • Price:

    $1.41 FREE Shipping over $49

Autoship: &Save

$1.34(Save an extra 5%)

Simply select Autoship at checkout for easy regular deliveries.

Why Autoship?
  • FREE access to chat with licensed vets 7 days a week
  • Save 5% on all future Autoship orders.
  • No fees, no commitments - cancel Autoship anytime.
In stock

This item requires prescription approval. Details

Medications ship separately. Delivery times may vary. Details

Add to Cart

We'll collect your pet's prescription information at Checkout.

cw-icon-heart Created with Sketch. Add to Favorites

Keeping your horse’s bones and joints healthy is a key ingredient in keeping her happy and healthy, and if she has osteoarthritis, it is an even bigger priority for you. Equioxx Tablets for Horses is an easy-to-administer oral tablet that works to help relieve the pain and inflammation caused by your horse’s osteoarthritis. Just one convenient, daily dose lasts up to 24 hours and can help improve your horse's mobility. Equioxx has been tested on more horses in safety studies than any other NSAID. Free of steroids, Equioxx Tablets for Horses offer a safe and effective way for you to help keep your equine friend feeling fit as a filly.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.


EQUIOXX (firocoxib) is approved to control pain and inflammation associated with osteoarthritis (degenerative joint disease) in horses.

Possible Side Effects

The most common side effects associated with EQUIOXX (firocoxib) therapy involve the tongue, lips and skin of the mouth and face (erosions and ulcers of the mucosa and skin) and the kidney. Gastrointestinal, kidney and liver problems have also been reported with other NSAIDs.

Drug & Food Interactions

Pease consult with your veterinarian for any Food and Drug interaction concerns.


Horses should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. Treatment with EQUIOXX (firocoxib) should be terminated if signs such as inappetance, colic, abnormal feces, or lethargy are observed. See package insert for full information.

Please note product may arrive in a Chewy Pharmacy vial, manufacturer packaging is shown for reference.

  1. Prescribing Information

See all items by Equioxx

  • Item Number
  • Administration Form
  • For Use With
  • Generic Name
  • Common Brand Name(s)
  • Product Form
  • Health Condition
    Cushing's Disease
  • Drug Type


Recommended Dosage

EQUIOXX (firocoxib) Oral Paste or EQUIOXX Tablets can be used at a dosage of 0.045 mg/lb (0.1 mg/kg) body weight for up to 14 days of treatment. EQUIOXX Oral Paste: Each marking on the syringe will treat 250 lbs of body weight, and each notch corresponds to approximately a 50 lb weight increment. To deliver the correct dose, round the horses body weight up to the nearest 50 lb increment (if the body weight is an exact 50 lb increment, do not round up). 1) While holding plunger, turn the knurled ring on the plunger to the left and slide the knurled ring along the plunger shaft so that the side nearest the barrel is at the appropriate 50 lb weight notch, aligning the arrow on the plunger with the notch on the ring. 2) Lock the ring in place by making turns to the right. Ensure it is locked (it should no longer slide) EQUIOXX Tablets: The recommended dosage of EQUIOXX Tablets is one 57 mg tablet, for oral administration in horses weighing 800-1300 lbs, once daily for up to 14 days. The overall duration of treatment with any firocoxib formulation in horses, including EQUIOXX Oral Paste or Tablets will be dependent on the response observed, but should not exceed 14 days. EQUIOXX may be given with or without food. Please see package insert for additional information.

Storage Instructions

Room Temperature 20-25C


What is an NSAID?

NSAID stands for Non-Steroidal Anti-Inflammatory Drug. NSAIDs are primarily used to treat inflammation and mild to moderate pain.

What makes EQUIOXX different than other NSAIDs?

EQUIOXX is the first non-steroidal anti-inflammatory drug (NSAID) of the coxib class used to control pain and inflammation associated with osteoarthritis in horses that has been approved for use in the U.S. As a coxib class NSAID, EQUIOXX targets COX-2 (cyclooxygenase-2), which helps generate chemicals called prostaglandins that are responsible for pain and inflammation, while sparing COX-1 (cyclooxygenase-1), which helps maintain normal bodily functions such as blood flow to the kidneys and gastric mucosal protection.

Most NSAIDs currently approved for use in horses inhibit both COX-1 and COX-2. Firocoxib, the active ingredient in EQUIOXX Brand Products is a highly selective inhibitor of COX-2.

What do I do in case my horse receives more than the prescribed amount of EQUIOXX?

Consult your veterinarian if your horse receives more than the prescribed amount of EQUIOXX.

Rating: 4.7 of 5 stars 4 Reviews 4 Reviews 4.8 out of 5 Stars

Filter reviews by star rating

100% Recommend

100% of reviewersrecommend this product

Rating: 4.7 of 5 stars 4.8 / 5

You've Already Reviewed This Item

4 Reviews

Showing 4 Reviews

  • 4 out of 5 stars

    difficult to order

    By equioxx on Jun 15, 2021

    I have been using equioxx for my horse for over a year. When I saw Chewy had a good price, I decided to order from them since I also buy dog and cat food from Chewy. Unfortunately the process to order was an ordeal and It took 3 tries to get it sorted out. My vet repeatedly approved the prescription, and something would "happen" to make the order not go through on the Chewy end. I got emails that were confusing from chewy. I nearly gave up and the medication finally arrived. I hope it will be easier next time.

    You liked it! Something went wrong. Please try again later. Report
  • 5 out of 5 stars

    Seems to be working well

    By Andrea on Jun 25, 2021

    It seems to be assisting rather well with my teen/senior horse. He takes the chewable in the morning and seems to have more pep in his step the rest of the day. He was diagnosed with ringbone 2 weeks ago.

    You liked it! Something went wrong. Please try again later. Report
  • 5 out of 5 stars

    Great drug for pain

    By Dynamo on Aug 20, 2021

    This product is great for horses with arthritis. Helps them move better

    You liked it! Something went wrong. Please try again later. Report
  • 5 out of 5 stars

    Equioxx 57 mg.

    By Flash on May 27, 2021

    Excellent product. Excellent price and received my order quickly. Highly recommend Chewy for my prescription items

    You liked it! Something went wrong. Please try again later. Report