NexGard Chewable Tablets for Dogs, 24.1-60 lbs

Prescription Item

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Count: 3 treatments
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NexGard is a tasty bite-sized beef-flavored chewable tablet used to kill adult fleas before they lay eggs to help prevent infestations, plus it kills ticks in pets eight weeks or older, weighing four or more pounds. The fast-acting formula provides safe and effective year-round protection when given monthly. And since it comes in a chewable tablet form, it’s easy to give to your pet as a tasty treat or disguise it in your pet’s favorite wet food.


Kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of black-legged tick, American dog tick, Lone Star tick and brown dog tick infestations in dogs and puppies eight weeks of age and older, weighing four pounds or greater, for one month.

Possible Side Effects

Please contact your veterinarian if your pet starts vomiting.

Drug & Food Interactions

There are no known contraindications for the use of NexGard.


The safe use of NexGard in breeding, pregnant or lactating females has not been evaluated. Use with caution in pets with a history of seizures.

  1. Prescribing Information

See all items by NexGard

  • Item Number
  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Generic Name


  • Common Brand Name(s)


  • For Use With


  • Brand

    Merial, Boehringer Ingelheim

  • Breed Size

    Medium Breeds, Large Breeds

  • Product Form

    Chewable Tablet

  • Health Condition

    Fleas, Ticks

  • Drug Type




Recommended Dosage

Consult your veterinarian for proper dosing instructions.

Storage Instructions

Store at or below 86°F with excursions permitted up to 104°F.

Dosage Chart

NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg).

Dog Weight NexGard per Month Afoxolaner Per Chewable (mg)
4 to 10 lbs 1 chewable tablet 68 mcg 11.3
10.1 to 24 lbs 1 chewable tablet 136 mcg 28.3
24.1 to 60 lbs 1 chewable tablet 272 mcg 68
60.1 to 121 lbs 1 chewable tablet 272 mcg 136

Over 121.0 lbs. Administer the appropriate combination of chewable.

NexGard can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the doses have been lost or if vomiting occurs within two hours of administration, re-dose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule.


How does NexGard kill fleas?

NexGard contains the ingredient afoxolaner. Afoxolaner kills fleas by over-stimulating their nervous system.

Does NexGard also kill ticks?

NexGard also kills the Lone Star tick, Black-legged tick, American Dog tick and Brown dog tick.

How old does my dog need to be in order to take NexGard?

NexGard (afoxolaner) is safe and effective for use in puppies 8 weeks of age or older, weighing 4 pounds or more.

How long does it take NexGard to kill fleas?

In a study, NexGard killed 100% of fleas within 24 hours.

Why am I seeing more fleas on my pet after administering NexGard?

NexGard stimulates the flea’s nervous system, causing them to rise to the top of your dog's haircoat as they die.

Does NexGard have an expiration date?

Two years from the date of manufacture. You can locate the expiration date on the outside of the package of NexGard.

How long after administering NexGard to my dog can he be bathed or go swimming?

Because NexGard is an oral product, swimming or bathing has no effect on NexGard. Your dog’s coat can get wet immediately after taking NexGard.

Can I use it if my dog is on medication?

In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, nonsteroidal anti-inflammatory drugs (NSAIDs), anesthetics, and antihistamines.

Is NexGard safe to use on any breed of dog?

NexGard is safe and effective in any breed of dog when used as directed.

Can NexGard be used on cats and other pets?

No. NexGard should be used on dogs only.

Can I administer it more than once a month?

Don't re-administer NexGard before the month is through. It keeps working for a full 30 days.

Are there any side effects of NexGard?

The most commonly reported adverse reactions found in NexGard for Dogs include vomiting, itching, diarrhea, lethargy and lack of appetite. Use with caution in dogs with a history of seizures.

Customer Reviews
26 Reviews 26 Reviews 5 out of 5 Stars

100% Recommend

100% of reviewersrecommend this product

5 / 5

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  • So far, so good

    By on

    We are trying this instead of the topicals. Our dog, who is very sensitive and has allergies, has had no reaction so far to this tablet. We live in the woods not far from Old Lyme, Ct, where Lyme disease was first diagnosed. We have had no ticks ( which are rampant here) on our dog since giving him a NexGuard 10 days ago. He is 55 lbs. and we are giving him the 24 to 60 lbs dose. It is much easier to giv a pill than put liquid on the back.

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  • Finally,Relief from fleas!

    By on

    I had an infestation of fleas..I tried everything, the topical spot on, all kinds, flea baths, diatomaceous earth, I have 5 big, inside dogs... it was heartbreaking to see them scratching all the time, I bought the Nexguard and within 3 days, all fleas gone... it is the best , I will definitely keep using it I don't want to go through that flea situation again!

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  • Easy, easy easy!

    By on

    When it comes to keeping away fleas and ticks, Nexgard does the trick! I have been using this for about 4 months now and I haven't had any issues with my dog getting fleas or ticks! Not to mention how easy it was ordering Nexgard from Chewy.com. First time I purchased Nexgard I paid just over $100 for 3 months. I was able to get it from Chewy.com for nearly half that and they even called the vet for the prescription. I loved that! I work during the hours my vet is open so getting there to purchase more was going to be an issue. I was so pleased when I found out I could not only purchase it online but get it at half the price and didn't have to take time to call the vet to get a prescription.

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  • We love NexGard! So much easier compared to flea and tick drops

    By on

    We have used flea and tick drops on our dogs for years. It is always a struggle to apply the drops and make sure they stay dry for 24 hours after application. NexGard is more expensive compared to the drops but in our opinion definitely worth it. So much easier and our pups now look forward to taking their flea and tick prevention! We highly recommend NexGard!

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  • Highly Recommend

    By on

    I've always used frontline in the past but never seemed to work! I would always find fleas on my dog. I'm so happy something like this came out in the market & surprisingly works awesome! I love the fact that it's a chewable so you have no worries of it getting on anything and having less effect of it doing its job!

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  • Always perfect

    By on

    I placed my order online at 6:00 pm while in the airport in Atlanta on my way to Florida. I had forgotten to give my dog his flea and tick medication and we were heading to “flea and tick central”. The next day, less than 24 hours later, the medication was delivered. You just can’t do any better than that! This is the way all things should be run. Chewy.com for president!

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  • So much better than topical!

    By on

    I love that I can give my dogs a pill instead of putting that messy topical solution on them & it works great for fleas & ticks. SO happy Chewy has a pharmacy now!!! Best price I’ve found for this product.

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  • Very Effective Treatment

    By on

    This is a well-tolerated flea & tick preventative! There was another brand I was using that was a little cheaper but it caused nausea and seemed to wear off before the month was out. I highly recommend this brand because my dog eats it like a treat (administer it at feeding time to reduce tummy upset) Very good flea/tick control, the fleas don't even bite :D

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  • Working in Atlanta

    By on

    Thank God for this pill. Seresto collar did nothing. Advantix ii did nothing but did control ticks. Gave the dog the nexgard and the next morning dead fleas all over the dog. Tried diatomaceous earth, dusted the pen with sevin, finally dogs are getting relief. Battling all summer!!

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  • Veterinarian advised

    By on

    My vet advised me to use this product and I'm completely satisfied with the results. Patches has been on this medication for over a year and I only recently began ordering it from Chewy: cheaper than what I was paying at a competitor.

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