ADVANTAGE MULTI Topical Solution for Dogs, 20.1-55 lbs, (Red Box), 6 Doses (6-mos. supply) -

Advantage Multi Topical Solution for Dogs, 20.1-55 lbs, (Red Box)

By Advantage Multi
Rated 4.2821 out of 5 stars
Prescription Item
Pet Weight
Pet Weight

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$129.71Chewy Price
$123.22Autoship Price
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Medications ship separately. Delivery times may vary.

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About This Item


Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Advantage Multi for Dogs is a broad-spectrum topical solution prescribed by veterinarians to provide a convenient monthly application to help alleviate canine companions from symptoms caused by pesky parasites. This easy-to-use topical solution helps to treat circulating microfilariae in heartworm-positive canines, fights against adult fleas, treats and controls flea infestations, and sarcoptic mange, along with common intestinal parasites including roundworms, hookworms and whipworms—this medication may also prevent heartworm disease in some dogs.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Learn More About Advantage Multi From Our Team of Experts

ReviewsWrite a Review

Rated 4.2821 out of 5 stars
78 Ratings
Would recommend to a friend

78 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Shelbi on Apr 30, 2023

Does not work

This is WAY too expensive to not work. Very disappointed. My boy still got fleas and had some ticks on him after an adventure hiking through the woods. Did not work AT ALL. I'll definitely be sticking to nexgard or bravecto from here on out. He also had some what of an allergic reaction to it. His belly and ears got bright red and irritated. His nips got inflamed and sore. He was ok after a few days but still. Couldn't believe it. I found a tick right next to wear I had applied the medication. Just crazy.

Rated 5 out of 5 stars
By Alyssa on Apr 14, 2023

This saved my dogs life!

Not only does this protect dogs from fleas & ticks but not many people know it can also be used for part of a new heartworm treatment.. so thanks to this medication my rescue is heartworm FREE! He’ll need to stay on this for the rest of his life so it never comes back, but a topical every month that he’d actually need anyway is SO much better then painful injections that we never would’ve been able to afford. Thank you!

Rated 5 out of 5 stars
By Devlin on May 22, 2023

Great price, Excellent service

Had a run around with vet's office about this medication for the dog, but the pharmacists at Chewy were a tremendous help with situation. Got product quickly... Thanks

Rated 5 out of 5 stars
By Ginger on Jan 14, 2023


Over the years I have used this type of product given by mouth. However, after going through a horrible experience watching my dog develop tumors all over his body and no doubt in his brain causing seizures I decided a topical form is better for the dog. The medicine does not have to travel in its system the way anything oral does. It works well for me and I highly recommend it. Chewy give a nice discount especially when placing it on auto ship. My local Vet does not carry the medication.

Rated 5 out of 5 stars
By NKD1945 on Mar 17, 2023

Easy to apply

Advantage Multi is easy to apply. I feel confident that I am protecting my dog against several possible maladies!

Rated 1 out of 5 stars
By winston on Oct 1, 2022

really smelly

We normally use Revolution, but of course supply chain issues led us here - the next option our vet recommended as our dog can’t have chewables. Let me tell you, this product absolutely stinks and that smell lingers for days. It made our dog very greasy for about 24 hours, and it stinks more than 48 hours later. His mouth smells like metal (which I’ve read many reviews saying this was common). The second Revolution comes back in stock, we’ll be going back to that, which means 5 months of heartworm medication will go to waste. Maybe I’m being dramatic but the smell is intolerable. At least he’s protected? That’s the only silver lining for us.

Rated 3 out of 5 stars
By advantage on Oct 4, 2022

Subbed for Revolution, will be switching back

This does the job as far as prevention, however it creates a huge mess on the back of our dog’s neck and smells. We’ve been using Revolution for years, and like others have switched over while it’s been on back order. As soon as it’s back in stock we will be switching back. This product creates a huge mess on the back of our dog’s neck and we have to cover furniture to prevent it from getting on everything. We’ve been dreading giving this medication each month because it creates such a mess.

Rated 5 out of 5 stars
By Debbie on Jan 29, 2023

Advantage Multi

My order was shipped in record time with no hiccups. Chewy is the absolute best!

Rated 5 out of 5 stars
By Denise on Jan 23, 2023

Always On Time

Appreciate your prompt timing as always on our orders.

Rated 5 out of 5 stars
By Chewy2022 on Aug 13, 2022

Just What My Puppy Needed

I have used this medicine for a number of years and it always been effective. My puppy does not like to swallow pills and this is a great alternative. It was easy to order and delivery was quick.