Nutramax Denamarin with S-Adenosylmethionine & Silybin Chewable Tablet Liver Supplement for Dogs, 150 count

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About This Item

Details

  • Support your dog’s liver health with veterinarian-recommended Denamarin.
  • Denamarin for dogs contains S-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione—one of the liver’s main detoxifying agents.
  • The silybin (a bioactive component of milk thistle extract) found in Denamarin is more bioavailable than standardized milk thistle extract.
  • The liver, one of your pet’s most vital organs, is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system.
  • Denamarin undergoes thorough quality inspections to ensure your dog receives a safe, high-quality product.

Ingredient Information

Instructions

FAQ

Learn More About Nutramax From Our Team of Experts

Combined Power of SAMe and Silybin

Denamarin combines the power of S-adenosylmethionine (SAMe) and silybin to help support healthy liver function in pets.

#1 Veterinarian Recommended

Denamarin is the #1 veterinarian recommended liver support brand.

*Survey conducted among small animal veterinarians who recommended liver support supplements.

The Denamarin Difference

The Silybin (a bioactive component of milk thistle extract) found in Denamarin is more bioavailable than standardized milk thistle.

Unmatched Quality

Each batch of Cosequin undergoes rigorous quality inspections, ensuring that your pet receives a high-quality joint health supplement.

About Nutramax

Family owned and operated since 1992, Nutramax Laboratories exceeds the industry standard for animal health supplements. We develop high-quality products for joint, liver, digestive health, and overall wellness.

Shop Nutramax

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Questions & Answers

21 Customer Questions

Does this come in powder form? My dog is not taking the tablets, yet she needs them.

Can this be crushed and put in a pill pocket, even though it says to take on an empty stomach?

Answer by Chewy • Aug 27, 2020
While these tablets may be chewed, they do not have to be in order to be effective. This medication should be administered on an empty stomach at least 1 hour before eating. If you must mask with food it is recommended to use no more than one tablespoon.

What flavor are these?

Answer by Chewy • Jul 25, 2018
This supplement is pork liver flavored.

Is this product Made in the USA?

Answer by Chewy • Dec 03, 2020
This supplement is manufactured in Lancaster, South Carolina.
Reviews
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4.1
Rated 4.1 out of 5 stars
1643 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

68% Positive

Effectiveness

77% Positive

Ingredients

71% Positive

Long-Term Benefits

76% Positive

952 Customer Reviews

Rated 5 out of 5 stars
By Laura on Feb 3, 2026

Liver Supplement for senior dog

I was worried that he wasn't going to like them but he gets them for a "treat" - you will need to put them on a high shelf or in a cupboard because they were quite

I was worried that he wasn't going to like them but he gets them for a "treat" - you will need to put them on a high shelf or in a cupboard because they were quite popular for sniffing and trying to eat the bottle. the "150-count" is just 2, 75-count bottles, that's cool, just don't get this expecting one giant bottle.

Rated 5 out of 5 stars
By Ozzy & Gorgeous on Jan 11, 2026

My rescue pom has HMD- Birth defect, affects liver

I had labs redone on my 7 pound rescue dog a few days ago at the vet before dental cleaning. Which led to us unexpectedly finding out he has HMD (Hepatic Microvascular

I had labs redone on my 7 pound rescue dog a few days ago at the vet before dental cleaning. Which led to us unexpectedly finding out he has HMD (Hepatic Microvascular Dysplasia). This is a lifelong genetic condition that affects his liver. His vet gave us Denamarin & We’ve now begun the switch to a lower fat & protein diet- still sticking to fresh & dehydrated w/ more plant based & easily digestible meats- rabbit & fish. He gets his labs redone in a few weeks. Hoping for the best

Rated 5 out of 5 stars
By Barbara on Jan 23, 2026

Easy chewable

This chewable version is so much easier to use than the other type of pill (capsule). Buried in Braunschweiger it becomes a treat (it is bitter so needs something

This chewable version is so much easier to use than the other type of pill (capsule). Buried in Braunschweiger it becomes a treat (it is bitter so needs something to disguise the taste according to the package - they suggest liver paste). Needs taken on an empty stomach - an hour before a meal or 2 hours after according to package.

Rated 1 out of 5 stars
By Jennifer on Dec 29, 2025

Too big, do not recommend

These pills are marketed as chewables but for a picky dog who won’t take pills, they aren’t appetizing enough to be chewed. Very large, crumbly, no scent though

These pills are marketed as chewables but for a picky dog who won’t take pills, they aren’t appetizing enough to be chewed. Very large, crumbly, no scent though apparently they are liver- flavored. I’m better off with the regular pills and trying to mask it in a small amount of food for the amount of effort it takes to try to get these monsters down.

Rated 3 out of 5 stars
By Diane on Jan 19, 2026

Denamarin

They seem soft. They break when cutting. They don't have a moisture pack in them. Not sure the other bottle did but I didn't have trouble cutting them from the

They seem soft. They break when cutting. They don't have a moisture pack in them. Not sure the other bottle did but I didn't have trouble cutting them from the last bottle.

Rated 5 out of 5 stars
By Josue on Feb 2, 2026

Liver maintenance and promotion

Denamarin has helped to my German shepherd. It's very expensive so I'm glad chewy give us gift cards. Great store and great products !

Denamarin has helped to my German shepherd. It's very expensive so I'm glad chewy give us gift cards. Great store and great products !

Rated 1 out of 5 stars
By tamara on Jan 31, 2026

He would not ingest it.

I cut this in quarters for my small dog and he just sniffed at it. I tried adding it to his food and when he ate it he threw up

I cut this in quarters for my small dog and he just sniffed at it. I tried adding it to his food and when he ate it he threw up

Rated 2 out of 5 stars
By Barbara on Jan 8, 2026

Subscrpt was supposedly being cancelled

I called a while back to cancel my subscription but it was overlooked. My dog refuses to take the meds. I know things get busy and this kind of thing happens.

I called a while back to cancel my subscription but it was overlooked. My dog refuses to take the meds. I know things get busy and this kind of thing happens.

Rated 5 out of 5 stars
By Barbara on Nov 18, 2025

Great for dogs with liver issues

My dog has taken a variety of medications, including steroids, for several years due to an autoimmune disease and has high liver numbers. My vet specialist suggested

My dog has taken a variety of medications, including steroids, for several years due to an autoimmune disease and has high liver numbers. My vet specialist suggested giving her Denamarin. She’s doing very well and the vet credits Denamarin as contributing to her health.

Rated 5 out of 5 stars
By Janet on Oct 19, 2025

Lowered my dog's liver numbers.

My dog's liver enzymes were high and taking this brought her numbers down dramatically. She didn't like the taste. So I crushed the pill and mixed it with a small

My dog's liver enzymes were high and taking this brought her numbers down dramatically. She didn't like the taste. So I crushed the pill and mixed it with a small amount of wet cat food. It's hard to give my dog pills because she smells the medication and refuses to take it regardless of what I put the pill in. I felt like I was running out of ways to give her meds. Wet cat food works great! I know the bottle says to give on an empty stomach, but it still brought her numbers down. And it was my vet who used the word "dramatically."