Nutramax Denamarin with S-Adenosylmethionine & Silybin Chewable Tablets Liver Supplement for Dogs, 30 count

Deal
Skip image gallery
Slide 1 of 13

At a Glance

  • All Lifestages
  • All Breeds

$42.74 Autoship Price
(-5%)
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$44.99 Chewy Price
($1.50 /ea)
Promo, Spend $100, Get $30 eGift Card with code NEWYEAR
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
In Stock
FREE 1-3 day delivery
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

Details

  • Support your dog’s liver health with veterinarian-recommended Denamarin.
  • Denamarin for dogs contains S-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione—one of the liver’s main detoxifying agents.
  • The silybin (a bioactive component of milk thistle extract) found in Denamarin is more bioavailable than standardized milk thistle extract.
  • The liver, one of your pet’s most vital organs, is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system.
  • Denamarin undergoes thorough quality inspections to ensure your dog receives a safe, high-quality product.

Ingredient Information

Instructions

FAQ

Learn More About Nutramax From Our Team of Experts

Combined Power of SAMe and Silybin

Denamarin combines the power of S-adenosylmethionine (SAMe) and silybin to help support healthy liver function in pets.

#1 Veterinarian Recommended

Denamarin is the #1 veterinarian recommended liver support brand.

*Survey conducted among small animal veterinarians who recommended liver support supplements.

The Denamarin Difference

The Silybin (a bioactive component of milk thistle extract) found in Denamarin is more bioavailable than standardized milk thistle.

Unmatched Quality

Each batch of Cosequin undergoes rigorous quality inspections, ensuring that your pet receives a high-quality joint health supplement.

About Nutramax

Family owned and operated since 1992, Nutramax Laboratories exceeds the industry standard for animal health supplements. We develop high-quality products for joint, liver, digestive health, and overall wellness.

Shop Nutramax

Frequently bought together

Questions & Answers

22 Customer Questions

my shihtzu will not eat or take this pill even if its crushed up, it tastes terrible. what are you alternatives

Does this come in powder form? My dog is not taking the tablets, yet she needs them.

What flavor are these?

Answer by Chewy • Jul 25, 2018
This supplement is pork liver flavored.

Can this be crushed and put in a pill pocket, even though it says to take on an empty stomach?

Answer by Chewy • Aug 27, 2020
While these tablets may be chewed, they do not have to be in order to be effective. This medication should be administered on an empty stomach at least 1 hour before eating. If you must mask with food it is recommended to use no more than one tablespoon.
Reviews
Write a Review
4.1
Rated 4.1 out of 5 stars
1612 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

67% Positive

Effectiveness

77% Positive

Ingredients

71% Positive

Long-Term Benefits

76% Positive

941 Customer Reviews

Rated 5 out of 5 stars
By Ozzy on Jan 11, 2026

My rescue pom has HMD- Birth defect, affects liver

I had labs redone on my 7 pound rescue dog a few days ago at the vet before dental cleaning. Which led to us unexpectedly finding out he has HMD (Hepatic Microvascular

I had labs redone on my 7 pound rescue dog a few days ago at the vet before dental cleaning. Which led to us unexpectedly finding out he has HMD (Hepatic Microvascular Dysplasia). This is a lifelong genetic condition that affects his liver. His vet gave us Denamarin & We’ve now begun the switch to a lower fat & protein diet- still sticking to fresh & dehydrated w/ more plant based & easily digestible meats- rabbit & fish. He gets his labs redone in a few weeks. Hoping for the best

Rated 1 out of 5 stars
By Jennifer on Dec 29, 2025

Too big, do not recommend

These pills are marketed as chewables but for a picky dog who won’t take pills, they aren’t appetizing enough to be chewed. Very large, crumbly, no scent though

These pills are marketed as chewables but for a picky dog who won’t take pills, they aren’t appetizing enough to be chewed. Very large, crumbly, no scent though apparently they are liver- flavored. I’m better off with the regular pills and trying to mask it in a small amount of food for the amount of effort it takes to try to get these monsters down.

Rated 2 out of 5 stars
By Barbara on Jan 8, 2026

Subscrpt was supposedly being cancelled

I called a while back to cancel my subscription but it was overlooked. My dog refuses to take the meds. I know things get busy and this kind of thing happens.

I called a while back to cancel my subscription but it was overlooked. My dog refuses to take the meds. I know things get busy and this kind of thing happens.

Rated 5 out of 5 stars
By Janet on Oct 19, 2025

Lowered my dog's liver numbers.

My dog's liver enzymes were high and taking this brought her numbers down dramatically. She didn't like the taste. So I crushed the pill and mixed it with a small

My dog's liver enzymes were high and taking this brought her numbers down dramatically. She didn't like the taste. So I crushed the pill and mixed it with a small amount of wet cat food. It's hard to give my dog pills because she smells the medication and refuses to take it regardless of what I put the pill in. I felt like I was running out of ways to give her meds. Wet cat food works great! I know the bottle says to give on an empty stomach, but it still brought her numbers down. And it was my vet who used the word "dramatically."

Rated 5 out of 5 stars
By Barbara on Nov 18, 2025

Great for dogs with liver issues

My dog has taken a variety of medications, including steroids, for several years due to an autoimmune disease and has high liver numbers. My vet specialist suggested

My dog has taken a variety of medications, including steroids, for several years due to an autoimmune disease and has high liver numbers. My vet specialist suggested giving her Denamarin. She’s doing very well and the vet credits Denamarin as contributing to her health.

Rated 5 out of 5 stars
By kathy on Nov 12, 2025

Professional & helpful

For the Denamarin, chewy technician Destiny was very helpful in fixing my autoship so my dog doesn’t miss out on his liver pills. He seems to be doing just fine

For the Denamarin, chewy technician Destiny was very helpful in fixing my autoship so my dog doesn’t miss out on his liver pills. He seems to be doing just fine with these pills. I might need to switch to capsules because he doesn’t like the flavor.

Rated 1 out of 5 stars
By HELEN on Dec 2, 2025

It was a chewable version of the pill,

The dog would not take the pill even when masked with meats or cheese, now the dog will not chew the hard tablet. Have to chop it and put it in the kibble. Not really

The dog would not take the pill even when masked with meats or cheese, now the dog will not chew the hard tablet. Have to chop it and put it in the kibble. Not really worth the effort.

Rated 1 out of 5 stars
By S on Nov 24, 2025

Won’t buy again

It’s not Chewys fault- but this is a very large chalky tablet and our dog is supposed to take 2 on an empty stomach- they are hard to break down and ultimately we

It’s not Chewys fault- but this is a very large chalky tablet and our dog is supposed to take 2 on an empty stomach- they are hard to break down and ultimately we had to stop using them

Rated 1 out of 5 stars
By Jaime on Oct 6, 2025

Big Hard Round

this says chewable and it is nowhere near that! I have to crush it and try to figure out a way to give it to my dog but the problem is it says to give it without

this says chewable and it is nowhere near that! I have to crush it and try to figure out a way to give it to my dog but the problem is it says to give it without food. it is not chewable it is bigger than the normal pill. VERY VERY DISAPPOINTED And will never buy again! Don’t be fooled by the “chewable” lie!

Rated 5 out of 5 stars
By Rob on Dec 4, 2025

Works

My Maltipoo Milo is 13, has been on this for years, because he takes phenobarbital and keppra. Seems to keep his levels even....

My Maltipoo Milo is 13, has been on this for years, because he takes phenobarbital and keppra. Seems to keep his levels even....