PetAlive EaseSure-S Brain & Nervous System Support Dog & Cat Supplement, 2-oz bottle

By PetAlive
Rated 4.6744 out of 5 stars
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$35.17Chewy Price
$39.95Chewy Price
$33.41Autoship Price
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About This Item

  • Non-addictive herbal supplement for brain and nervous system functioning in dogs and cats.
  • Supports the management of common symptoms of seizures, epilepsy, and stress-induced episodes by supporting an overactive nervous system.
  • Natural tonic promotes calm or stimulated nerves as needed and reduces involuntary muscle movements and twitching.
  • Crafted by experts to help calm or stimulate nerves as needed.
  • Comes in a convenient liquid drop form, so dosing can be adjusted to treat furry friends of all sizes. This can also be used with PetAlive's EaseSure-M homeopathic drops.

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Top IngredientsProprietary Formula, Passion Flower (Herb), Skullcap (Herb)...Active Ingredients: Citicoline, Coconut Oil, L-Theanine...Active Ingredients: L-Carnitine, Alpha Lipoic Acid, L-Leucine...Organic Black MacaKrill Oil, Astaxanthin, Medium Chain Triglycerides...
Breed SizeSmall Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Extra Small Breeds, Medium Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...
LifestageAdult, Senior, Puppy, KittenAdult, SeniorSeniorAdultAdult, Senior, Puppy, Kitten
Health FeatureBrain HealthVitamins & Minerals, Brain HealthBrain Health, Senior CareBrain HealthSkin & Coat Health, Hip & Joint Support, Heart Care
Food FormSupplementSupplementSupplementPowderSupplement
Food FlavorFruits & Vegetables

Questions & Answers

23 Customer Questions

Do I just give this to my dog when hes having a seizure..or everyday
Answer by ChewyMay 07, 2018
The Supplement can be given for maintenance daily or when needed.

What does it do
Answer by ChewyMar 23, 2018
EaseSure-S is a 100% safe, herbal supplement that supports symptoms commonly associated with epilepsy, seizures, or stress-related episodes in pets with an overactive nervous system. Using a scientific blend of ingredients known to support soothed nerves and natural equilibrium, the concentrated liquid formula promotes nervous system health, stability, and brain function.

Will this product help calm tremors
Answer by ChewyOct 06, 2017
This product will work for tremors by calming the nervous system.

I read elsewhere on website that because of formula changes, it is recommended to use both Easesure-S along with E asesure-M to control seizures - is that correct or has owners with pets seen that using Easesure -S works well by itself?
Answer by ChewyDec 17, 2019
This can also be used with PetAlive's EaseSure-M homeopathic drops but it is not required.

ReviewsWrite a Review

Rated 4.6744 out of 5 stars
43 Reviews
Would recommend to a friend

43 Customer Reviews

Rated 5 out of 5 stars
By LOVE on May 19, 2022


Bought this to try on my Cockapoo that has seizures and some other issues neurologically, and it truly has helped. He doesn’t seem as antsy/anxious and hasn’t had anymore seizures (knock on wood)… Will continue to use this!

Rated 5 out of 5 stars
By Volunteer on Feb 8, 2022

Great product for tremors!

My 16 year old maltipoo has neurological tremors, and it’s really hard on her body. We had a CBD powder we really liked, but they stopped selling it for some reason. She also doesn’t have any teeth, so we couldn’t do chews. I decided to try this product out and I’m glad I did. I give it to her once a day and it stops her trembling. I definitely recommend this.

Rated 5 out of 5 stars
By CalmBrain on Nov 20, 2021


We're so grateful to find this supplement as it really ease our boy's seizure. It really minimized the recurrence and severity. We unfortunately lost him due to CHF but it helped him tremendously in his last months. Thank you!

Rated 5 out of 5 stars
By NYYNKGRL27 on Sep 29, 2021

Cautiously Optimistic

My one cat is 16 1/2. He began exhibiting signs of Feline Dementia, i.e. howling, prowling & antagonizing his brother, for a good portion of the night. The vet tech gave me a few suggestions including administering a low dose of melatonin. These remedies did not help. I didn't want drugs of any kind so I searched for natural remedies. This product seemed ideal. I give him 2 doses daily, am & pm. So far, his nightly shenanigans have disappeared. The reason I say "cautiously optimistic" is that I'm afraid he'll build an immunity to the product & revert to his old ways. It remains to be seen. However, I would highly recommend cat owners to give this a try. The product is working splendidly.

Rated 5 out of 5 stars
By cassie on Oct 29, 2021

Dog seizures

My dog has been suffering from idiopathic epilepsy for almost a year and with many med changes, she was still getting them frequently. Adding this has helped decrease them. It took about a month or so to show progress but it has helped.

Rated 5 out of 5 stars
By MonicaLewis on Jul 26, 2021

It worked for me

My 10 year old Shih Tzu had his first seizure on April 18, 2020. It wasn't super severe (minor seizing, loss of bladder control) but it was scary and unexpected. He then had them every other month like clockwork (June 10, August 15, October 21), thankfully never increasing in severity. I ordered this supplement on November 12, 2020 and started him on it right away. He's picky but he ate his food normally even with this dropped right on top. He had another seizure on December 22, 2020 (on his usual, weird schedule) and I was worried that this product didn't work. But that December seizure was his last one. He's not had one since (July 26, 2021 is the date of this review) and I haven't changed anything outside of this supplement. Having your beloved pet get older and seeing their health decline is one of the worst feelings ever. Especially when you can't figure out what's causing the issue. I'm so relieved that this supplement seems to be keeping his seizures at bay and has not caused any other problems. I'd recommend this to anyone and would pray that it works for your pet like it did for mine.

Rated 5 out of 5 stars
By Bianca on Dec 20, 2021

Wonderful , love it

Excellent product , I love it , make a difference in my dog

Rated 5 out of 5 stars
By Nina on Jun 12, 2021

So Far So Good!!!

My 12 yo Baby Girl has suffered from seizures now and then since she was young. I count nine total, but one was really bad! She stopped breathing, and no heartbeat!! Luckily she came to and pulled through! The ER thought it was a Syncopal Episode, but had her heart checked out and luckily all looked good! I think that one was when she was about 5. This year 2021 was bad! She had four (nearly half of her lifetime total!) with two in 8 days, and she screamed in pain during them which she had never done! After $4K+ at the ER they think she had a kidney infection. After a month of meds she is doing great! They wanted to put her on anti-seizure meds, but I ran across this on Chewy and decided to give it a try. 3+ months later not one seizure!! Not sure how much to attribute to it, but you can’t argue with the results! And have it on hand in case (God Forbid!) she ever has one again.

Rated 3 out of 5 stars
By nick on Aug 5, 2021

Poor packing

Item was wrapped in bubble wrap with the cap loose and the ingredients spilled out.

Rated 5 out of 5 stars
By Drops on Apr 21, 2021

Seizure Drops

My cat has been having very bad seizures. I could not stand to see her in that state so I decided to try out some medicine. This one works the best for her. She is very picky about what you put in her food and she barely tasted it. I haven’t seen her have a seizure in a while now.