VETOQUINOL Zylkene Equine Behavior Support Apple Flavor Powder Horse Supplement 2000 mg, 20 count -

Vetoquinol Zylkene Equine Behavior Support Apple Flavor Powder Horse Supplement 2000 mg, 20 count

By Vetoquinol
Rated 4.0556 out of 5 stars
$160.99Chewy Price
$152.94Autoship Price
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About This Item


  • The only veterinary supplement formulated with alpha-casozepine, a natural cow’s milk protein known to effectively help relax horses and ponies.
  • Non-drowsy formula provides a sense of calm while maintain mental alertness, without tranquilizing or sedating effects.
  • Perfect to use for all stressful situations your horse may encounter, on or off the farm, and is backed by research for behavior management.
  • Free of lactose and preservatives, so it’s ideal for horses with sensitives; chosen by veterinarians and dog behaviorists for short-term or long-term use.
  • Easy to give once daily at meal time, with an apple flavor that most horses love.

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Nutritional Information

Feeding Instructions

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Questions & Answers

4 Customer Questions

i bought a 9 year old mare for my daughter to just ride for fun, she has never bucked or kicked but she constantly looking for something to spook on and freaks over every tiny thing. would this be an item that would get her to settle down?
Answer by ChewyMay 29, 2018
The milk-sourced alpha-casozepine in this product is known to promote relaxation in babies, and it works in a similar way in an adult horse or pony, giving them a sense of comfort and contentment to help them cope with stress or adapt to new situations.

How long does the calming effect last after dosing?
Answer by ChewyFeb 17, 2023
On average the calming effect can last between 6-8 hours. This will vary between horses as there are many variables that will affect the duration such as age, sex, weight, etc.

How long after administration does it take effect? Can it be used on a case by case basis? (i.e. farrier visit)
Answer by ChewyOct 22, 2018
It could take 1-2 hrs. before you can see an effect. This depends on sex, age and metabolism of the individual horse. It can be used for specific events only.

Do you need a Prescription to purchase this product.
Answer by ChewyAug 12, 2018
A prescription is not required to purchase this supplement powder.

ReviewsWrite a Review

Rated 4.0556 out of 5 stars
18 Ratings
Would recommend to a friend

18 Customer Reviews

Rated 5 out of 5 stars
By Ringworm on Jan 9, 2023

I’ve tried everything - this is all that works!

I tried all the calming supplements I could find to help my very scared of the world barrel horse. Nothing worked. Even the very expensive products. Now this is. It cheap, but it works. Can you give your horse a single dose the day of an event and expect to see results? No. I’ve played with the dosing to figure it out & here’s what I suggest: If you have an event on a Sunday, start the horse on their first dose on Thursday morning. Give every morning and every night through Sunday night. I really found that the loading dose of three days was necessary. But with that, my dude is cool and happy, shows no signs of agitation in the stall, doesn’t spook at things he shouldn’t, and just seems chill and happy to be at his shows. I now actually give this to even my horses who don’t “need” it if they seem to be excitable or hard travelers. I do believe by calming their anxiety I’m preventing ulcers and just plain unhappiness.

Rated 5 out of 5 stars
By WTBuffChick on Jul 30, 2021

Takes the edge off

My mare can get more sensitive when she travels to new places, especially after a tire explosion on the trailer that damaged the side of the trailer earlier this year. I administer it as directed, beginning 3 days before we travel and throughout the show. Zylkene takes the edge off so that she isn’t anxious in the trailer or in the stalls as shows. She does not scream when she was alone even when she is in heat, and does not require as much time to be worked down as she does when she doesn’t have it. This also helps to keep her from getting sore and fatigued. While working your horse down is a normal part of competition, working them until they are too sore and exhausted because they get fractious from other horses or scary arenas isn’t realistic or fair to them. I think some users expect a sedated effect where the horse becomes dull, which is unrealistic for a non-sedative product. Zylkene takes the edge off so that the horse can stay focused on what they are doing rather than everything around them. My mare is genuinely quiet and relaxed so that the entire show experience is positive. She’s a picky eater that won’t eat apples, carrots or any kind of horse treat, and there was no problem getting her to eat this with her grain.

Rated 1 out of 5 stars
By Candy on Nov 18, 2021

Disappointed in the expensive product

Did not work on my horse. Tried on another and didn’t work. Return for money back quaratee. Haven’t beed refunded as of yet

Rated 5 out of 5 stars
By Linda on Jul 26, 2021

It Works!!

I tried this on my horse prior to our last horse show. (We had been to a show two weeks previously and he was way too spunky. My ride consisted of hanging on for dear life.) I mixed the packet of powder in his grain on Thursday, Friday and Saturday mornings. We showed late Saturday morning and he was a dream to ride. This did not make him lethargic at all; he was alert and had his typical English stride. He listened to me. I don't care what it costs. It works. (Besides, an accident with broken ribs and collapsed lung will cost you more....) I highly recommend it (even gave three packets to a friend to use on her spirited horse).

Rated 5 out of 5 stars
By Suemcd on Sep 13, 2021

Wonderful Product

This product has made a huge in difference in my horse's anxiety level as he is on stall rest for a tendon injury. He is able to stand quietly for most of the day now and allow the healing to occur. Chewy's price is the best as usual!

Rated 1 out of 5 stars
By Laurel on Jun 22, 2021

didn’t notice a difference

Bought it to help get my gelding to load into a trailer. It didn’t help he acted the same way he always does. He also still acted terrified of the fly spray. I couldn’t tell any difference.

Rated 5 out of 5 stars
By Ariel on Mar 3, 2021

Best product ever

This has helped my mare in ways I can’t even explain. She has thus innate sense of calm. My vet recommended and it has really helped us in our training!

Rated 3 out of 5 stars
By quarterhorsemorgan on Nov 16, 2020

maybe it worked too well?

I tried this on my fidgety, unreliable quarter horse to see if it would calm her down for my young neighbor to be able to handle her better. She seemd more relaxed; not nipping at her pasture mate and more approachable for tacking. However, when my friend rode her, she said she acted as if she was overmedicated-would wander off gait and then jerk back into the gait again. Then when she was going downhill she pooked so badly my friend fell off-this has never happened in the 4 years we have had her. So I am not using the medication for now. I am going to have a good equine dental exam to make sure that is not the problem because she has trouble with bits.

Rated 5 out of 5 stars
By Jennifer on Aug 29, 2019

Love this stuff!

my herd bound, hot mare is now happy in her work and able to focus on the job at hand. Unfortunately it is now a prohibited substance with USEF, so they recommend it be withdrawn 7 days prior to competition.

Rated 5 out of 5 stars
By Horsemama on Jul 27, 2019

Very Helpful

While not inexpensive this seems to be doing the trick for our 5 year old thoroughbred that has been on stall rest for 4 months. We tried some other supplements prior to this one but have had the best results so far with this. It seems to have taken the edge of for him and he is not getting wound up over every little thing like he was previously.