VetSmart Formulas Critical Immune Defense Mushroom & Turmeric Compound Dog & Cat Supplement, 6.3-oz bottle, 1 count

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About This Item

Details

  • Helps boost your pet’s “good” cells to help fight diseases.
  • Designed to deliver the strength, quality and efficacy of veterinarian solutions.
  • Can be used at the same time as chemotherapy, steroid treatments and other medications.
  • Helps remove harmful pathogens like viruses and bacteria, which can cause inflammation and infections.
  • Made in the USA without artificial colors, flavors or wheat.

Ingredient Information

Instructions

FAQ

Learn More About VetSmart Formulas From Our Team of Experts

Questions & Answers

9 Customer Questions


Will this work for warts and skin tags?


How many scoops in a container?

Answer by ChewyJun 09, 2022
This supplement includes 60 scoops per bottle (approximately 30 day supply).

Are the ingredients organic?

Answer by ChewyMar 04, 2024
While VetSmart Formulas cannot confirm organic certification, all of their ingredients are natural and human-grade, ensuring their safety and quality. VetSmart Formulas use the highest quality ingredients available from reputable vendors that they have worked with for many years. Each batch is standardized and is delivered with a legal Certificate of Analysis after careful inspection. The quality control does not stop there. When the ingredients arrive in the USA they are quarantined, inspected again, and strict testing is performed for any bacteria, fungus, or other abnormalities. Once the ingredients are approved and released, they go through additional rounds of quality control and are manufactured in facilities that are FDA-certified by the U.S. government. VetSmart Formulas follow the highest standards that veterinarians require for our products. This exhaustive process ensures the highest standard of quality and safety for your pets.

How long will this last for two adult cats and how much do I give them?

Answer by ChewyJul 20, 2020
As dosage will vary by pet weight and condition, the length of time the container lasts will vary. The dosage instructions may be located by clicking the “Feeding Instructions” tab, on the product page.

4.5
Rated 4.5 out of 5 stars
588 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Effectiveness

81% Positive

Form and Administration

79% Positive

Ingredients

80% Positive

Nutritional Value

78% Positive

237 Customer Reviews



Rated 1 out of 5 stars
By Nancy on Jan 16, 2026

Caution

We have two 10yrs old cats and two 2-3yrs old dogs. One dog has sensitive and cats are middle age. Thought an immune boost would be all around helpful. Eased cats

We have two 10yrs old cats and two 2-3yrs old dogs. One dog has sensitive and cats are middle age. Thought an immune boost would be all around helpful. Eased cats and dogs into this product over 3-4 days then full recommended dose. At day 6 we have one cat and one dog feeling unwell. Cat acts unwell, cry when picked up. 2 yrs old dog acting odd and unwell. I have discontinued immediately. Something is wrong.


Rated 5 out of 5 stars
By Gloria on Nov 11, 2025

I believe this is improving my dogs quality of life

My dog is 11 years old and has recently been sick. We thought we were going to have to put him down but he rallied and is still alive. The vet believes he has cushings

My dog is 11 years old and has recently been sick. We thought we were going to have to put him down but he rallied and is still alive. The vet believes he has cushings disease and after some research he fits all the criteria and I believe his is very advanced. Unfortunately, he needs steroids to help keep his inflammation from his arthritis down therefore he can't get the testing done to confirm Cushings and get the medication. Regardless, I did some research on natural remedies for Cushings. I started giving him this and the Melatonin and Lignans. Together I noticed a bit of a difference. He began parking up a bit and getting some tail wags. His panting isn't as bad and he seems less restless. We are almost through a whole bottle and I reordered another. He is very picky so I mix it with peanut butter and make him a peanut butter sandwich with it. He is basically palliative and with the cushings he's been losing a lot of weight despite rabidly eating. Regardless, I believe that this has gained us more time with our buddy and has given him some quality of life. He perks up and gives us tail wags. So I believe it has helped him and has been worth the money.


Rated 5 out of 5 stars
By Denise on Jan 16, 2026

Great product

I like that it uses natural ingredients like turkey tail mushrooms appealed to me as I use them for my own immune support.

I like that it uses natural ingredients like turkey tail mushrooms appealed to me as I use them for my own immune support.


Rated 5 out of 5 stars
By SANDRA on Sep 26, 2025

Cancer

My dog was diagnosed with stage 2 sarcoma. Surgery removed the mass but couldn't get it all. Within the year it grew back. Nothing else could be done. Called in

My dog was diagnosed with stage 2 sarcoma. Surgery removed the mass but couldn't get it all. Within the year it grew back. Nothing else could be done. Called in a hospice veterinarian to help with final plans when the time came. My regular veterinarian told me about turkey tail for cancer in dogs. I started using it twice daily in his food. In six weeks the mass was gone. It has been almost a year since I started using it. He still has cancer but turkey tail has slowed it. I'm grateful to still have my baby. He just turned 14. I'm grateful every day I have him. I use one bottle every month. Easy to mix in food.


Rated 5 out of 5 stars
By Mary on Oct 5, 2025

VetSmart formulas Critical Immune Defense

My Golden Retriever Jack was diagnosed by our vet with mouth cancer due to a malignant growth in his mouth. The vet removed as much of the growth as possible and

My Golden Retriever Jack was diagnosed by our vet with mouth cancer due to a malignant growth in his mouth. The vet removed as much of the growth as possible and gave him six months to live. We began giving Jack this mushroom and turmeric formula shortly thereafter. The vet re-examined him and was puzzled since the growth has shrunk and it wasn't spreading to his bones like he thought it would. It has now been over nine months, and our dog is now 12yrs. old and appears to have more energy. We will definitely continue using this product and recommend it. As another reviewer stated cancer hates mushrooms.


Rated 5 out of 5 stars
By Kym on Nov 22, 2025

1st using

Hoping this helps with his skin issues. On my second order, goes fast my dog is 120 pounds 3 scoops twice a day goes fast . Ordering again to see if any changes

Hoping this helps with his skin issues. On my second order, goes fast my dog is 120 pounds 3 scoops twice a day goes fast . Ordering again to see if any changes .


Rated 1 out of 5 stars
By Pamela on Sep 8, 2025

Critical Immune Defense

I've been giving my cat Critical Immune Defense for about two weeks now, mixing it with her wet food and Delectables Squeeze Up treats. Unfortunately, her fibrosarcoma

I've been giving my cat Critical Immune Defense for about two weeks now, mixing it with her wet food and Delectables Squeeze Up treats. Unfortunately, her fibrosarcoma on her ribcage doesn't seem to be shrinking. She's already had two surgeries, and a third might be necessary. I'm really hoping the CID will start working soon.


Rated 5 out of 5 stars
By Renee on Oct 24, 2025

More energy

After just one week of use Milo seems to have more energy and is a younger version of himself, wanting to play more. It's too soon to tell if it helps with his bumps

After just one week of use Milo seems to have more energy and is a younger version of himself, wanting to play more. It's too soon to tell if it helps with his bumps (which is the reason I'm trying it). He also loves the flavor and has no hesitation about eating his food with it mixed in.


Rated 1 out of 5 stars
By Linda on Nov 12, 2025

Made my dog sick

Started this to help boost my girls immune system but everytime I gave it to her, she threw it up. Very disappointed in the product. What a waste of money.

Started this to help boost my girls immune system but everytime I gave it to her, she threw it up. Very disappointed in the product. What a waste of money.


Rated 4 out of 5 stars
By Paul on Jan 5, 2026

To early to see results.

Dogs love to eat it on their food. To early to tell results of making lumps smaller

Dogs love to eat it on their food. To early to tell results of making lumps smaller